Christopher O. Fakunle

Structure and Synthesis of Anhydrobisfarnesol from Euphorbia lateriflora and Asymmetric Synthesis of (R)-Sesquilavandulol

Abstract Anhydrobisfarnesol has been isolated from the latex of Euphorbia lateriflora and assigned structure 4 on the basis of its spectroscopic properties. Its structure has been confirmed by synthesis using a photochemical isomerisation procedure. A similar approach has been used for the total synthesis of (R)-sesquilavandulol.

Chemistry of the meliacins (limonoids). The structure of melianin A, a new protomeliacin from Melia azedarach

Evidence is presented for the structures of a new protomeliacin (melianin A) and the related melianin B, which co-occur with gedunin (or 7-deacetoxy-7-oxogedunin), nimbolin A, fraxinellone, and cycloeucalenone in the wood extracts of Melia azedarach.

The structure of euphorianin, an ingol diterpenoid from Euphorbia poisonii

The residual uncertainty in the structure of euphorianin, an ingol diterpenoid from the latex of Euphorbia poisonii, has been resolved by nuclear Overhauser enhancement difference experiments which revealed the configuration at C-19 to be S. The 1H and 13C NMR spectroscopic properties of euphorianin and its transformation products are described.

X-Ray Crystal Structure Analysis of Deacetyldehydroeuphorianin: The Correct Structure of the Novel Pentacyclic Macrocyclic Diterpene, Euphorianin

Abstract The conversion of euphorianin to deacetyldehydroeuphorianin which was used in an X-ray crystal structure analysis is described. A new pentacyclic structure related to ingol tetraacetate is described for euphorianin.