Chunlin Liu

Two Sensitive Fluorescent BOPIM Probes with Tunable TICT Character for Low-Level Water Detection in Organic Solvents

Two novel Boron-fluorine derivatives bearing dimethylamino moieties, BOPIM-1 and BOPIM-2, were proposed as sensitive fluorescent sensors for low-level water quantification in organic solvents. Two BOPIMs exhibit typical phenomenon for an emission from a twisted intra-molecular charge transfer (TICT) state, the emission red shift and intensity weakening with solvent polarity. Introduction of trace amount of water to solvent resulted in fluorescent quenching, accompanied by the red shift of the emission, which was attributed to the formation of TICT excitation of BOPIMs by hydrolysis. A quantification method to detect water content was developed, described by a linear equation lgII0

A Boron 2-(2′-pyridyl) Imidazole Fluorescence Probe for Bovine Serum Albumin: Discrimination over Other Proteins and Identification of Its Denaturation

\lg \frac{I}{I_0}

Red-emitting benzo[e]indolium probes for HSA based on the TICT characteristics

vs. lg φw in the range of φw (volume fraction of water) 0.001~0.01, 0.01~0.1, respectively. The experiment results of determination of water in real 1, 4-dioxane (Diox) samples proved that this method can be used in practical application.

Recognition and quantification of HSA: A fluorescence probe across α-helices of site I and site II

Multicolor mechanochromic luminescent (MCL) materials are promising candidates in fundamental science and practical applications. In this paper, a series of novel smart luminescent compounds based on a cyanostyrene unit, NAIF, NA-15C5, NAPM, NAIP and NAPF, have been developed. NAIF, NAPM, NAPF and NAIP all exhibit aggregation-induced emission (AIE) characteristics and individually show red, orange, yellow and green emission in their aggregated state. Luminogens NA-15C5 and NAPM display reversible tricolor-changing MCL behaviors. NAIF and NAIP show bicolor switching mechanochromic phenomena. Additionally, different molecular packing modes of two crystalline polymorphs, NAPM-y and NAPM-o with bright yellow and orange luminescence color, rationally explain the tricolor-changing mechanochromic mechanism. Moreover, luminogen NAIP can be used as ink-free rewritable paper.

Smart On‐Off Switching Luminescence Materials with Reversible Piezochromism and Basichromism

Boron 2‐(2′‐pyridyl) imidazole complex (BOPIM) derivatives, BOPIM‐1 and BOPIM‐2, involving twisted intra‐molecular charge transfer (TICT) characteristic, were investigated to probe bovine serum albumin (BSA). BOPIM‐1 was demonstrated to be an efficient fluorescence probe to discriminate BSA from other proteins including human serum albumin (HSA). The encapsulation of BOPIM‐1 in the hydrophobic subdomain IIA of BSA inhibited the TICT state and resulted in 70‐fold emission enhancement of BOPIM‐1. Besides, it was found that BOPIM‐1 could distinguish denatured BSA from the native, due to the difference of 15 nm emission wavelength at least. The denaturation of BSA leads to the exposure of binding sites and resulted in an increase in the accessibility of the fluorophore to the BSA cavity, which made a great contribution to the further restraint of TICT state of BOPIM‐1. The tracking of BSA denaturizing process was easily achieved, through the change of BOPIM‐1 emission wavelength from 485 to 465 nm. Thus, a promising pharmacological dual‐functional probe was provided for both the selective recognization of BSA and the identification of denatured BSA from the native.