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Dive into the research topics where Claire Milburn is active.

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Featured researches published by Claire Milburn.


Bioorganic & Medicinal Chemistry Letters | 2008

Novel benzimidazole derivatives as selective CB2 agonists.

Daniel Page; Elise Balaux; Luc Boisvert; Ziping Liu; Claire Milburn; Maxime Tremblay; Zhongyong Wei; Simon Woo; Xuehong Luo; Yun-Xing Cheng; Hua Yang; Sanjay Srivastava; Fei Zhou; William Brown; Miroslaw Tomaszewski; Christopher Walpole; Leila Hodzic; Stephane St-Onge; Claude Godbout; Dominic Salois; Keymal Payza

The preparation and evaluation of a novel class of CB2 agonists based on a benzimidazole moiety are reported. They showed binding affinities up to 1nM towards the CB2 receptor with partial to full agonist potencies. They also demonstrated good to excellent selectivity (>1000-fold) over the CB1 receptor.


Archive | 2005

Therapeutic Compounds: Pyridine as Scaffold

Kosrat Amin; Johan Broddefalk; Helene Desfosses; Emma Evertsson; Ziping AstraZeneca R D Montréal Liu; Claire Milburn; Karolina Nilsson; Maxime Tremblay; Christopher Walpole; Zhongyong AstraZeneca R D Montreal Wei; Hua AstraZeneca R D Montreal Yang


Archive | 2006

Novel 3-Bicyclocarbonylaminopyridine-2-Carboxamides or 3-Bicyclocarbonylaminopyrazine-2-Carboxamides

Kosrat Amin; Johan Broddefalk; Yantao Chen; Helene Desfosses; Ziping Liu; Claire Milburn; Karolina Nilsson; Maxime Tremblay; Christopher Walpole; Zhongyong Wei; Hua Yang


Letters in Drug Design & Discovery | 2010

5-Sulfonamide Benzimidazoles: A Class of Cannabinoid Receptors Agonists with Potent In Vivo Antinociception Activity

Daniel Page; Zhongyong Wei; Ziping Liu; Maxime Tremblay; Helene Desfosses; Claire Milburn; Sanjay Srivastava; Hua Yang; William J. Brown; Christopher Walpole; Mirek Tomaszewski; Stephane St-Onge; Etienne Lessard; Kemal Payza; Rosemarie Panetta; Xiao Hong Yu; Thierry Hong Groblewski


Archive | 2005

Compounds, compositions containing them, preparations thereof and uses thereof ii

John Wei; Claire Milburn; Helene Desfosses; Daniel Page; Sanjay Srivastava; Christopher Walpole; Hua Yang


Archive | 2008

Therapeutic compounds: pyridine as scaffoid

Kosrat Amin; Helene Desfosses; Ziping Liu; Karolina Nilsson; Christopher Walpole; Hua Yang; Johan Broddefalk; Emma Evertsson; Claire Milburn; Maxime Tremblay; Zhongyong Wei


Bioorganic & Medicinal Chemistry Letters | 2008

Corrigendum to “Novel benzimidazole derivatives as selective CB2 agonists” [Bioorg. Med. Chem. Lett. 18 (2008) 3695–3700]

Daniel Page; Elise Balaux; Luc Boisvert; Ziping Liu; Claire Milburn; Maxime Tremblay; Zhongyong Wei; Simon Woo; Xuehong Luo; Yun-Xing Cheng; Hua Yang; Sanjay Srivastava; Fei Zhou; William Brown; Miroslaw Tomaszewski; Christopher Walpole; Leila Hodzic; Stephane St-Onge; Claude Godbout; Dominic Salois; Kemal Payza


Archive | 2007

COMPUESTOS TERAPÉUTICOS: PIRIDINAS Y PIRAZINAS COMO ANDAMIOS

Tremblan Maxime C; Oaks Thousand; Johan Broddefalk; Kosrat Amin; Karolina Nilsson; Helene Desfosses; Zhongyong Wei; Walpole Christopher; Chen Yantao; Claire Milburn; Ziping Liu; Hua Yang


Archive | 2006

N-!2-TERT-BUTIL-1-(TETRAHIDRO-2H-PIRAN-4-ILMETIL)-1H-BENCIMIDAZOL-5-IL!-SULFAMIDO DERIVADOS SUSTITUIDOS, PROCEDIMIENTOS DE PREPARACION, COMPOSICIONES QUE LOS CONTIENEN Y APLICACIONES

Christopher Walpole; Hua Yang; Daniel Page; Claire Milburn; Helene Desfosses; Wei Zhong-Yong


Archive | 2006

DERIVADOS DE N-!2-TERT-BUTIL-1-(TETRAHIDRO-2H-PIRAN-4-ILMETIL) -1H-BENCIMIDAZOL-5-IL)-N-METIL-BENCENO- SULFONAMIDA, PROCEDIMIENTO DE PREPARACION, COMPOSICIONES FARMACEUTICAS CONTENIENDOLOS Y APLICACIONES

Christopher Walpole; Hua Yang; Daniel Page; Ziping Liu; Claire Milburn; Tremblay Maxime C

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