Claire Robertson

Reconstruction plates for stabilization of mid-shaft clavicle fractures: Differences between nonlocked and locked plates in two different positions

Reconstruction plates permit contouring to the irregular anatomic shape of the clavicle. This study evaluated the biomechanical stability of locking and nonlocking clavicle reconstruction plates for treating midshaft, transverse fractures, comparing anterior-inferior to superior plate position. Twenty-four synthetic clavicles with mid-shaft fractures were repaired with either a locking or nonlocking clavicle reconstruction plate in either the anterior-inferior or superior plate position (n = 6/group). Repaired constructs were tested in axial compression, axial torsion, and cantilever bending failure. In compression, anterior-inferior plates were significantly stiffer than superior plates and locked plates stiffer than nonlocked. In torsion, anterior-inferior plates were stiffer, with a significant interaction term that favored anterior-inferior locked and superior nonlocked plates. In cantilever bending, superior plates had a significantly higher bending failure load and stiffness. Anterior-inferior plates failed at a significantly lower load ( approximately 40 N or approximately 4 kg), which could potentially occur in the postoperative period.

Biomechanical comparison of kyphoplasty versus a titanium mesh implant with cement for stabilization of vertebral compression fractures.

Study Design. In vitro biomechanical investigation. Objective. To evaluate differences in biomechanical stability of vertebral compression fractures repaired using balloon kyphoplasty versus a titanium mesh implant. Summary of Background Data. Vertebral compression fractures may be stabilized using an expandable balloon followed by cement injection. There are small but finite risks of endplate fracture and cement extravasation with this procedure. Alternative techniques may affect cement injection volumes, height maintenance, and biomechanical stability but require investigation. Methods. Four male human cadaveric spines from T2 to L5 were used in this study. After determining bone mineral density, individual vertebral bodies were dissected and inspected for previous fractures or additional exclusion criteria. In the remaining vertebral bodies (n = 48) anterior wedge fractures were created using a materials testing machine. Fractured vertebral bodies were systematically randomized to be repaired either with balloon kyphoplasty or with titanium mesh implant and polymethylmethacrylate bone cement, using image intensified fluoroscopy. Anterior vertebral body height (cm) was measured initially, after mechanically creating an anterior wedge fracture, after repairing the compression fracture with either technique, and after recompressing the vertebral body following a 24-hour cement polymerization period. Data for cement injection volume (mL) and height maintained following testing (cm) were compared between repair groups using a 1-way analysis of variance (P < 0.05). Data for stiffness (N/mm), yield load (N), and ultimate load (N) were compared between intact bodies and repaired bodies using a 2-way analysis of variance (P < 0.05). Results. There was significantly less cement injected (P < 0.001) and significantly greater height maintained (P < 0.025) with the titanium implant group compared to the kyphoplasty group. There were no significant differences in biomechanical stability between the 2 groups (P > 0.05). Conclusion. The titanium implant was biomechanically equivalent to the kyphoplasty repair while necessitating less cement and providing greater height maintenance in vitro. Improvements in pain and function could not be specifically addressed in this in vitro study and should be evaluated in a clinical case series.

Biomechanical Comparison of Locking versus Nonlocking Volar and Dorsal T-plates for Fixation of Dorsally Comminuted Distal Radius Fractures

Objectives: The purpose of this study was to gain insight into the effect of plate location and screw type for fixation of extra-articular distal radius fractures with dorsal comminution (Orthopaedic Trauma Association Type 23-A3.2). Methods: Sixteen pairs of cadaver radii were randomized to four plating configurations: dorsal locking, dorsal nonlocking, volar locking, and volar nonlocking. A standard 1-cm dorsal wedge osteotomy was used. Cyclic axial loads were applied for 5000 cycles. Stiffness and fragment displacement were recorded at 500 cycle-intervals. Pre- and postcyclic loading radiographs were analyzed. An axial load to failure test followed and construct stiffness and failure strength recorded. Biomechanical data were analyzed using a two-way analysis of variance (P < 0.05). Failure modes were descriptively interpreted. Results: Cyclic testing data revealed no difference between constructs at any interval. Within all construct groups, displacement that occurred did so within the first 500 cycles of testing. Pre- and postcyclic loading radiographic analysis showed no differences in construct deformation. Load to failure testing revealed no differences between groups, whereas volar constructs approached significance (P = 0.08) for increased failure strength. Dorsal constructs failed primarily by fragment subsidence and fragmentation, whereas volar constructs failed by plate bending. Conclusions: No difference in all measured biomechanical parameters supports equivalence between constructs and surgeon discretion in determining operative method. Minimal fragment displacement and construct deformation during physiological testing support previous data that early postoperative motion can be recommended. Fragment displacement that occurs does so in the early periods of motion.

Biomechanical Analysis of Supracondylar Humerus Fracture Pinning for Slightly Malreduced Fractures

Background: The most common position of malreduced type III supracondylar humerus (SCH) fractures is internal rotation and medial collapse of the distal fragment. The purpose of this study was to determine the effect of SCH fracture rotational deformity on stability with various pin configurations. Specifically, is the biomechanical stability lost when an SCH fracture is pinned in slight malreduction (compared with anatomical pinning) improved by adding a third pin? Methods: Sixty-four synthetic humeri were sectioned in the mid-olecranon fossa to simulate an SCH fracture. Specimens were randomized to an anatomically reduced group or a group with 20 degrees of distal fragment internal rotation (n = 32 per group). Each was randomized to one of 4 pin configurations: 2 laterally divergent pins, 2 crossed pins, 3 laterally divergent pins, or 2 lateral with 1 medial pin (n = 8 per group). All fractures were stabilized with 1.6 mm (0.062 in) Kirschner wires. Models were tested in extension, varus, and valgus for 10 cycles between 5 N and 50 N. Internal and external rotations were tested between ±1 Nm. Data for fragment stiffness (newtons per millimeter or newton millimeters per degree) were analyzed with a 2-way analysis of variance (p < 0.05). Results: Internally rotated fractures were significantly less stable than the anatomically reduced group for external rotation, internal rotation, and varus loading regardless of pin configuration. Within the malreduced group, 3-pin configurations were more stable than 2-pin configurations in internal rotation, varus, and extension loading. Two lateral divergent pins were similar to 2 crossed pins, except in extension, where 2 lateral pins had greater stiffness. Conclusions: Construct stiffness for malreduced specimens after pinning was less than those pinned with an anatomical reduction when loaded in varus, internal rotation, and external rotation. For simulated fractures with residual internal rotation, the addition of a third Kirschner wire compared with an anatomically reduced 2-crossed-pin configuration resulted in increased stiffness of the model for all loading directions. Clinical Relevance: Consider a 3-pin pattern, either 3 laterally divergent pins or 2 lateral pins and 1 medial pin, for SCH fractures when a less than complete anatomical reduction is obtained.

An evaluation of fracture stabilization comparing kyphoplasty and titanium mesh repair techniques for vertebral compression fractures: is bone cement necessary?

Study Design. In vitro biomechanical investigation using human cadaveric vertebral bodies. Objective. To evaluate differences in biomechanical stability of vertebral compression fractures (VCFs) repaired using an expandable titanium mesh implant, with and without cement, as compared with standard balloon kyphoplasty. Summary of Background Data. Vertebral augmentation, either in the form of vertebroplasty or kyphoplasty, is the treatment of choice for some VCFs. Polymethylmethacrylate, a common bone cement used in this procedure, has been shown to possibly cause injury to neural and vascular structures due to extravasation, embolization, and may be too rigid for an osteoporotic spine. Therefore, suitable alternatives for the treatment of VCFs have been sought. Methods. Individual vertebral bodies from 5 human cadaveric spines (from T4 to L5) were stripped of all soft tissues, and compressed at 25% of the intact height using methods previously described. Vertebral bodies were then randomly assigned to the following repair techniques: (1) conventional kyphoplasty, (2) titanium implant with cement, (3) titanium implant without cement. All vertebral bodies were then recompressed at 25% of the repaired height. Yield load, ultimate load, and stiffness were recorded and compared in these groups before and after treatment. Results. There were no differences in biomechanical data between intact groups, and between repaired groups. In all 3 treatment groups, yield load and ultimate load of repaired vertebrae were similar to that of intact vertebrae. However, the stiffness following repair was found to be statistically less than the stiffness of the intact vertebral body (P < 0.05 for all comparisons). Conclusion. Based on the biomechanical data, the titanium mesh implant with or without cement was similar to polymethylmethacrylate fixation by kyphoplasty in the treatment of VCFs. Avoiding the adverse effects caused by using cement may be the main advantage of the titanium mesh implant and warrants further study.

Biomechanical evaluation of transfacet screw fixation for stabilization of multilevel cervical corpectomies.

Study Design Cadaveric biomechanical investigation. Objectives To test the feasibility of transfacet screws as a minimally invasive posterior fixation device for the cervical spine by comparing the biomechanical stability of transfacet screws to lateral mass screws and rods in a multilevel cervical corpectomy model. Summary of Background Data Minimally invasive surgery (MIS) of the spine has gained increasing acceptance and popularity. However, a minimally invasive means of instrumenting the posterior cervical spine has yet to be discovered. Posterior transfacet screws have been described as a means of posterior fixation. In addition, they have the potential of being placed percutaneously through stab incisions. However, validation of transfacet screws in an unstable cervical model in which posterior instrumentation may be necessary has not been carried out till date. Methods Sixteen cadaveric cervical spines were randomized to transfacet or lateral mass instrumentation groups. The spines were tested in the following conditions: (a) intact, (b) after multilevel corpectomies with strut graft placement with stand-alone posterior fixation, and (c) with an additional anterior plate over the strut graft. Corpectomy site loading was measured with a custom-designed strut graft. Data were collected for spinal stiffness, range of motion, and strut graft loading, and was analyzed using 2-way analysis of variance (P<0.05). Results Stand-alone transfacet screw fixation was found to provide inferior spinal stability and resulted in increased spinal motion and graft loading compared with the other constructs (P<0.05 for all). Conclusions It is unclear what kind of mechanical stiffness is necessary to stabilize the cervical spine and obtain solid fusion. However, decreased stability and increased graft loading suggest that transfacet screws may not be the ideal method of posterior fixation to supplement multilevel anterior cervical corpectomies and fusions despite their potential as a minimally invasive method for posterior cervical instrumentation.