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Dive into the research topics where Clarice Gorenstein is active.

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Featured researches published by Clarice Gorenstein.


Revista Brasileira de Psiquiatria | 2013

Psychometric properties of the Beck Depression Inventory-II: a comprehensive review

Yuan-Pang Wang; Clarice Gorenstein

OBJECTIVE To review the psychometric properties of the Beck Depression Inventory-II (BDI-II) as a self-report measure of depression in a variety of settings and populations. METHODS Relevant studies of the BDI-II were retrieved through a search of electronic databases, a hand search, and contact with authors. Retained studies (k = 118) were allocated into three groups: non-clinical, psychiatric/institutionalized, and medical samples. RESULTS The internal consistency was described as around 0.9 and the retest reliability ranged from 0.73 to 0.96. The correlation between BDI-II and the Beck Depression Inventory (BDI-I) was high and substantial overlap with measures of depression and anxiety was reported. The criterion-based validity showed good sensitivity and specificity for detecting depression in comparison to the adopted gold standard. However, the cutoff score to screen for depression varied according to the type of sample. Factor analysis showed a robust dimension of general depression composed by two constructs: cognitive-affective and somatic-vegetative. CONCLUSIONS The BDI-II is a relevant psychometric instrument, showing high reliability, capacity to discriminate between depressed and non-depressed subjects, and improved concurrent, content, and structural validity. Based on available psychometric evidence, the BDI-II can be viewed as a cost-effective questionnaire for measuring the severity of depression, with broad applicability for research and clinical practice worldwide.


Journal of Clinical Psychology | 1999

Psychometric properties of the Portuguese version of the Beck Depression Inventory on Brazilian college students

Clarice Gorenstein; Laura Helena Andrade; Antonio Helio Guerra Vieira Filho; Teng Chei Tung; Rinaldo Artes

The psychometric properties of the Portuguese version of the Beck Depression Inventory were studied on a large Brazilian college student sample (N= 1,080; 845 women, 235 men). The BDI scores according to sociodemographic characteristics and mean individual item scores for total sample and by gender were compared. BDI scores tend to be higher for women, for those who work, and for the younger participants. The reliability of the inventory estimated by alpha coefficient was high for the total sample (.86) and subgroups. Factor analysis showed three factors for the total sample (low self-esteem, cognitive-affective, and somatic) and two for each gender. Women combined affective and low self-esteem whereas men combined somatic and low self-esteem in the same dimension. Discriminant analysis showed that BDI highly discriminates depressive symptomatology in college students and measures specific aspects of depression.


Journal of The International Neuropsychological Society | 2006

Self-reported and neuropsychological measures of impulsivity in pathological gambling.

Daniel Fuentes; Hermano Tavares; Rinaldo Artes; Clarice Gorenstein

Pathological Gambling is an impulse control disorder. Impulsivity has been investigated separately by neuropsychological tests and self-report scales. Although some studies have tried to correlate these approaches, their interaction has not been sufficiently explored among pathological gamblers (PG). In this study, we have compared 214 PG (162 with comorbidity and 52 with no comorbidity) to 82 healthy volunteers regarding the reaction time and number of errors at Go/No-go tasks, and scores on the Barratt Impulsiveness Scale (BIS). PG have committed more errors at the Go/No-go tasks and presented higher scores on the self-report scale. The neuropsychological tests and BIS composed a multinomial logistic model that discriminated PG from non-gamblers better than models having one or another type of measure. Impulsivity seems to be a multi-dimensional phenomenon, and PG a heterogeneous population in which different types of impulsivity are present.


Brazilian Journal of Medical and Biological Research | 2001

Psychometric properties of the Portuguese version of the State-Trait Anxiety Inventory applied to college students: factor analysis and relation to the Beck Depression Inventory

Laura Helena Andrade; Clarice Gorenstein; A.H.G. Vieira Filho; Teng Chei Tung; Rinaldo Artes

The psychometric properties of the Portuguese version of the trait form of the State-Trait Anxiety Inventory (STAI-T) and its relation to the Beck Depression Inventory (BDI) were evaluated in a large Brazilian college student sample containing 845 women and 235 men. STAI-T scores tended to be higher for women, singles, those who work, and subjects under 30 years. Factor analysis of the STAI-T for total sample and by gender yielded two factors: the first representing a mood dimension and the second being related to worrying or cognitive aspects of anxiety. In order to study the relation between anxiety and depression measures, factor analysis of the combination of the 21 BDI items and the 20 STAI-T items was also carried out. The analysis resulted in two factors that were analyzed according to the tripartite model of anxiety and depression. Most of the BDI items (measuring positive affectivity and nonspecific symptoms of depression) were loaded on the first factor and four STAI-T items that measure positive affectivity. The remaining STAI-T items, all of them measuring negative affect, remained in the second factor. Thus, factor 1 represents a depression dimension and factor 2 measures a mood-worrying dimension. The findings of this study suggest that, although widely used as an anxiety scale, the STAI-T in fact measures mainly a general negative affect.


Clinics | 2013

Assessment of depression in medical patients: A systematic review of the utility of the Beck Depression Inventory-II

Yuan-Pang Wang; Clarice Gorenstein

To perform a systematic review of the utility of the Beck Depression Inventory for detecting depression in medical settings, this article focuses on the revised version of the scale (Beck Depression Inventory-II), which was reformulated according to the DSM-IV criteria for major depression. We examined relevant investigations with the Beck Depression Inventory-II for measuring depression in medical settings to provide guidelines for practicing clinicians. Considering the inclusion and exclusion criteria seventy articles were retained. Validation studies of the Beck Depression Inventory-II, in both primary care and hospital settings, were found for clinics of cardiology, neurology, obstetrics, brain injury, nephrology, chronic pain, chronic fatigue, oncology, and infectious disease. The Beck Depression Inventory-II showed high reliability and good correlation with measures of depression and anxiety. Its threshold for detecting depression varied according to the type of patients, suggesting the need for adjusted cut-off points. The somatic and cognitive-affective dimension described the latent structure of the instrument. The Beck Depression Inventory-II can be easily adapted in most clinical conditions for detecting major depression and recommending an appropriate intervention. Although this scale represents a sound path for detecting depression in patients with medical conditions, the clinician should seek evidence for how to interpret the score before using the Beck Depression Inventory-II to make clinical decisions.


Psychological Reports | 1995

Scores of Brazilian University Students on the Beck Depression and the State-Trait Anxiety Inventories

Clarice Gorenstein; Sabine Pompéia; Laura Helena Andrade

The profiles of the Beck Depression Inventory and State-Trait Anxiety Inventory scores were obtained for a sample of Brazilian university students and compared with those of other studies. Subjects were 270 students from various universities in São Paulo, age 23.8 yr. (SD = 6.7 yr.). The mean Beck score for the total sample was 8.5 (SD = 7.0); according to the cut-off score of 16, 86 9% were considered normal, 7.5% had scores compatible with dysphoria, and 56% had scores indicative of depression. The mean State-Trait Anxiety score for the total sample was 40.7 (SD = 8.6). Considering one standard deviation as the threshold point, 17.8% could be considered low and 15.2% high on trait anxiety. Comparing our means with published data indicated that the Portuguese versions of the questionnaires are equivalent to original versions.


Revista Brasileira de Psiquiatria | 2002

Instrumentos para a avaliação dos transtornos alimentares

Silvia Freitas; Clarice Gorenstein; José Carlos Appolinário

This article describes the most useful instruments and methods that measure general and specific psychopathological features of the eating disorders. Thirteen self-report measures and two interviewer-based instruments are reviewed. The authors present, for each instrument, a brief description of its structure, their preferential utilization and the availability of a Portuguese version. At the end, a proposal of a psychometric protocol for the assessment of anorexia nervosa, bulimia nervosa and binge eating disorder is suggested.


Psychoneuroendocrinology | 2006

Melatonin levels in drug-free patients with major depression from the southern hemisphere

Livia A. Carvalho; Clarice Gorenstein; Ricardo A. Moreno; Regina P. Markus

The secretion of melatonin has been shown as abnormal in some depressed patients, but most such studies were conducted in the northern hemisphere and with severely depressed inpatients. The aim of this study was to evaluate melatonin excretion profiles in major depressive outpatients from São Paulo, Brazil, individually matched to well-screened healthy volunteers to examine whether melatonin abnormalities are also present in patients from the southern hemisphere, and in less severely ill patients. We analyzed 32 drug-free, depressed outpatients and 32 psychiatrically healthy volunteers matched for age and gender. We also examined a set of 15 drug-free depressed outpatients and 15 healthy volunteers that were matched not only for age and gender, but also for body mass index and season, all factors known to influence melatonin excretion in humans. All patients fulfilled DSM-IV criteria for major depression. We evaluated major urinary metabolite of melatonin, 6-sulphatoxymelatonin (aMT6s), produced over 24 h and divided into four periods (06:00-12:00, 12:00-08:00, 18:00-24:00 and 24:00-06:00 h). aMT6s measurements during the 24 and 6 h intervals were similar in the 32 depressed patients and 32 healthy volunteers matched for age and gender; further matching for body mass index and season did not alter the results. Our study supports others in which depressed patients were found to have similar melatonin levels than healthy volunteers. Melatonin excretion has been considered a physiological index for noradrenergic function, which in some studies were found to be altered than depressed patients. It is conceivable that the alteration of nocturnal melatonin in depressed patients occurs only in more severe depression.


Brazilian Journal of Medical and Biological Research | 2005

Validation of the Beck Depression Inventory for a Portuguese-speaking Chinese community in Brazil

Yuan-Pang Wang; Laura Helena Andrade; Clarice Gorenstein

The objective of the present study was to investigate the psychometric properties and cross-cultural validity of the Beck Depression Inventory (BDI) among ethnic Chinese living in the city of São Paulo, Brazil. The study was conducted on 208 community individuals. Reliability and discriminant analysis were used to test the psychometric properties and validity of the BDI. Principal component analysis was performed to assess the BDIs factor structure for the total sample and by gender. The mean BDI score was lower (6.74, SD = 5.98) than observed in Western counterparts and showed no gender difference, good internal consistency (Cronbachs alpha 0.82), and high discrimination of depressive symptoms (75-100%). Factor analysis extracted two factors for the total sample and each gender: cognitive-affective dimension and somatic dimension. We conclude that depressive symptoms can be reliably assessed by the BDI in the Brazilian Chinese population, with a validity comparable to that for international studies. Indeed, cultural and measurement biases might have influenced the response of Chinese subjects.


Journal of Psychopharmacology | 2009

Effect of antidepressants on melatonin metabolite in depressed patients.

Livia A. Carvalho; Clarice Gorenstein; R Moreno; Carmine M. Pariante; Regina P. Markus

Abstract Antidepressants increase melatonin levels, but it is still unclear whether this effect is related to the improvement of depressive symptoms or to unrelated pharmacological action of antidepressants. To answer this question, the effect of antidepressants on 6-sulphatoxymelatonin (aMT6s), the main melatonin urinary metabolite, was examined in drug-free depressed patients – most of them antidepressant-naive. aMT6s was evaluated in 34 depressed patients, before and after 8 weeks of placebo (n = 12) or antidepressant (n = 22; fluoxetine, duloxetine or Hypericum perforatum). Both groups showed an improvement of depressive symptoms after treatment compared to baseline (Hamilton Depression scores): 17.0 ± 1.4 vs. 9.0 ± 2.8, P = 0.007 for placebo, and 18.6 ± 1.1 vs. 11.8 ± 1.6, P < 0.001 for antidepressants). After treatment, aMT6s levels increased after antidepressants (P < 0.01), but not after placebo (P > 0.05). As depressive symptoms improved both in patients taking antidepressant and in those taking placebo, but an effect of antidepressants could only be seen in those taking antidepressants, we suggest that melatonin changes after antidepressants are more likely due to a pharmacological action of these drugs on melatonin secretion.

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Daniel Fuentes

University of São Paulo

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Yuan-Pang Wang

University of São Paulo

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