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Dive into the research topics where Claudio Iovino is active.

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Featured researches published by Claudio Iovino.


PLOS ONE | 2016

A Simple Novel Technique of Infrared Meibography by Means of Spectral-Domain Optical Coherence Tomography: A Cross-Sectional Clinical Study

Pietro Emanuele Napoli; Franco Coronella; Giovanni Maria Satta; Claudio Iovino; Raffaele Sanna; Maurizio Fossarello

Purpose To compare a novel spectral-domain optical coherence tomography (SD-OCT) technique with traditional lid transillumination for evaluation of meibomian glands (MGs) and to assess the relation of MG morphologic changes to the glandular atrophy. Design Evaluation of diagnostic technology. Participants Sixty-one patients with obstructive MGD (30 men, 31 women; age [mean ± standard deviation] 45.1 ± 12.1 years), and 75 control subjects (32 men, 43 women; 44.1 ± 12.5 years) were recruited in order to have a balanced distribution of glandular features. Methods Agreement between SD-OCT and lid transillumination examination for the detection of drop-out (partial or complete loss of MGs) and microscopic changes (i.e. shortening, distortion, segmentation and entanglement), as well as the relationship between morphological features and MG atrophy were evaluated. Main Outcome Measures Agreement between the two meibographic techniques, bias in symmetry of classification, and association analysis between microscopic changes and MG dropout. Results Overall agreement for all morphological features was substantial (Cohen kappa coefficient = 0.77; p<0.001), even if, the majority of disagreement occurred for cases with segmentation, where agreement was present in only 108 (81.82%) of 132 eyes with adequate images for interpretation, and where SD-OCT tended to diagnose more cases not detected by traditional lid transillumination (McNemar test, p<0.001). Moreover, segmentation and distortion pattern negatively correlated with the degree of drop-out, whereas shortening and entanglement pattern demonstrated only a weak correlation (Spearman’s ρ was -0.691, -0.491, -0.359, -0.385, respectively). Conclusions Each method has its advantages but in general there was close agreement between these meibographic techniques, particularly for MG dropout, which supports the reliability of our novel, simple and patient-friendly SD-OCT approach.


European Journal of Ophthalmology | 2018

Bilateral noncalcified astrocytic hamartomas in retinitis pigmentosa: Multimodal imaging evaluation over 8 years of follow-up

Claudio Iovino; Giamberto Casini; Enrico Peiretti

Purpose: To report the evolution of optic disk noncalcified astrocytic hamartomas in a patient with retinitis pigmentosa throughout 8 years of follow-up. Methods: Case report. Results: A 42-year-old white man with a diagnosis of retinitis pigmentosa was referred to our medical retinal center for the first time in 2010, for the development of a new optic nerve head lesion in the right eye. Fundus examination, fundus autofluorescence, fluorescein and green indocyanine angiography, spectral-domain optical coherence tomography were performed and confirmed the presence of a papillary noncalcified astrocytic hamartoma in the right eye. Four years later, multimodal imaging evaluation revealed in the left eye the presence of a first optic disk benign tumor, and in 2018, a second in the nasal retina, while in the right eye the sole papillary lesion increased slightly in size. Conclusions: Noncalcified astrocytic hamartomas can occur in patients with retinitis pigmentosa and can increase in size and number in time. A complete multimodal imaging evaluation is necessary to identify and classify any kind of new lesion that, as known, are associated with these group of hereditary retinal degenerations.


European Journal of Ophthalmology | 2018

Comparison of inverted flap and subretinal aspiration technique in full-thickness macular hole surgery: a randomized controlled study

Claudio Iovino; Giulia Caminiti; Mario Miccoli; Francesco Nasini; Giamberto Casini; Enrico Peiretti

Purpose: To compare the inverted flap and the subretinal aspiration technique for full-thickness macular hole (FTMH) surgery. Methods: Forty consecutive eyes with a stage IV FTMH were randomly assigned into 2 treatment groups. After core vitrectomy and perimacular internal limiting membrane (ILM) peeling, in group A, the subretinal remnant macular fluid was aspirated with a 41-G cannula after the air-fluid exchange procedure, while in group B, the technique of an inverted ILM flap was completed. Differences in postoperative best-corrected visual acuity (BCVA) and occurrence of intraoperative or postoperative complications between the 2 groups were evaluated. Results: All FTMHs were closed after the first surgery with no intraoperative or postoperative complications. In group A, 16 patients (80%) showed improvement of BCVA and 4 (20%) showed stabilization. In group B, 12 patients (60%) had improved BCVA, while 6 (30%) remained stable and 2 (10%) worsened. Postoperative BCVA for group A was significantly better than for group B (p = 0.022). Conclusions: The surgical techniques had similar rates of closure of FTMH, although BCVA outcomes were significantly better in the subretinal aspiration group.


International Medical Case Reports Journal | 2017

Resolution of pinguecula-related dry eye disease after argon laser photocoagulation

Pietro Emanuele Napoli; Raffaele Sanna; Claudio Iovino; Maurizio Fossarello

Purpose To describe an unusual case of unilateral, chronic symptoms and signs of dry eye, and recurrent episodes of ocular irritation related to pinguecula, which were refractory to prior medical treatments, successfully treated with argon laser photocoagulation. Methods A 36-year-old man presented with an elevated yellowish mass on his conjunctiva in his left eye, which was associated with dry eye symptoms and general discomfort, such as “tightening sensation” and “stiffness”. On clinical assessment, the left eye revealed a mild conjunctival injection, a fluorescein break-up time (FBUT) of 3.5 s, an abnormal fluorescein staining, and a Schirmer I test of 5 mm. Optical coherence tomography (OCT) imaging evidenced a height at the most elevated point of the pinguecula of 740 µm. The patient underwent argon-laser photocoagulation. Results After 2 weeks postoperatively, no residual of pinguecula or focal injection of the conjunctiva was detected by slit-lamp biomicroscopy and there was a significant improvement of clinical symptoms and signs: Schirmer I test and FBUT increased to 12 mm and >10 s, respectively, and fluorescein staining was absent. OCT imaging revealed a smooth structure of conjunctival contour, with a height of 404 µm. According to an ex juvantibus line of reasoning, definitive diagnosis was pinguecula-related dry eye disease. Conclusion Based on the concept that tear film instability and inflammation are two key components of the pathogenesis of dry eye, we coined the term “pinguecula-related dry eye disease,” which can be successfully treated by a complete, accurate removal of the lesion with argon laser photocoagulation.


Retinal Cases & Brief Reports | 2018

INTRAVITREAL AFLIBERCEPT IN THE TREATMENT OF POLYPOIDAL CHOROIDAL VASCULOPATHY ASSOCIATED WITH MORNING GLORY SYNDROME

Claudio Iovino; Maurizio Fossarello; Enrico Peiretti


Retina-the Journal of Retinal and Vitreous Diseases | 2018

OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY CHARACTERISTICS OF POLYPOIDAL CHOROIDAL VASCULOPATHY SECONDARY TO CHRONIC CENTRAL SEROUS CHORIORETINOPATHY

Enrico Peiretti; Claudio Iovino; Riccardo Sacconi; Giulia Caminiti; Giuseppe Querques


International Ophthalmology | 2018

Ocular surface and respiratory tract damages from occupational, sub-chronic exposure to fluorspar: case report and other considerations

Pietro Emanuele Napoli; Matteo Nioi; Claudio Iovino; Raffaele Sanna; Ernesto d’Aloja; Maurizio Fossarello


International Journal of Ophthalmology | 2018

Primary vitreoretinal lymphoma masquerading as acute posterior multifocal placoid pigment epitheliopathy

Francesca Frongia; Claudio Iovino; Nathalie Cassoux; Enrico Peiretti


Investigative Ophthalmology & Visual Science | 2017

Intraobserver variability of post-mortem corneal thickness measurements by using a portable OCT system.

Claudio Iovino; Pietro Emanuele Napoli; Matteo Nioi; Raffaele Sanna; Francesco Paribello; Ernesto D'Aloja; Maurizio Fossarello


Investigative Ophthalmology & Visual Science | 2017

OCT angiography characteristics in patients with chronic CSCR complicated with polypoidal choroidal vasculopathy

Rita Serra; Claudio Iovino; Giulia Caminiti; Maurizio Fossarello; Enrico Peiretti

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Matteo Nioi

University of Cagliari

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Rita Serra

University of Cagliari

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