Claudio Rosso

The Arthroscopic Latarjet Procedure for Anterior Shoulder Instability: 5-Year Minimum Follow-up

Background: The arthroscopic Latarjet procedure combines the benefits of arthroscopic surgery with the low rate of recurrent instability associated with the Latarjet procedure. Only short-term outcomes after arthroscopic Latarjet procedure have been reported. Purpose: To evaluate the rate of recurrent instability and patient outcomes a minimum of 5 years after stabilization performed with the arthroscopic Latarjet procedure. Study Design: Case series; Level of evidence, 4. Methods: Patients who underwent the arthroscopic Latarjet procedure before June 2008 completed a questionnaire to determine whether they had experienced a dislocation, subluxation, or further surgery. The patients also completed the Western Ontario Shoulder Instability Index (WOSI). Results: A total of 62 of 87 patients (64/89 shoulders) were contacted for follow-up. Mean follow-up time was 76.4 months (range, 61.2-100.7 months). No patients had reported a dislocation since their surgery. One patient reported having subluxations since the surgery. Thus, 1 patient (1.59%) had recurrent instability after the procedure. The mean ± standard deviation aggregate WOSI score was 90.6% ± 9.4%. Mean WOSI domain scores were as follows: Physical Symptoms, 90.1% ± 8.7%; Sports/Recreation/Work, 90.3% ± 12.9%; Lifestyle, 93.7% ± 9.8%; and Emotions, 88.7% ± 17.3%. Conclusion: The rate of recurrent instability after arthroscopic Latarjet procedure is low in this series of patients with a minimum 5-year follow-up. Patient outcomes as measured by the WOSI are good.

The role of platelets in the treatment of Achilles tendon injuries.

To systematically review the current in‐vivo evidence for the use of platelet‐concentrates (PRP) in the treatment of Achilles tendinopathy and Achilles tendon ruptures in animal models and human applications. A systematic search of PubMed, CINAHL, EMBASE, CCTR, and CDSR was performed for animal and human studies on the effect of platelet‐concentrates in the treatment of Achilles tendinopathy and ruptures using the terms “Achilles tendon and platelet.” The systematic search revealed a total of 149 papers. After excluding duplicates and cases of overlapping data, studies not focusing on in vivo evidence in terms of treatment or outcome, studies without any intervention, studies with unacceptable high attrition, one Chinese and one Swedish study, the remaining 14 manuscripts were included. The key finding of our study is evidence in support of a statistically significant effect of platelet concentrates in the treatment of Achilles tendon ruptures in vivo in animal models and human application, consistent with a medium to large sized effect. This effect is most likely attributable to fastened and enhanced scar tissue maturation. There was no evidence for a beneficial effect of platelets in Achilles tendinopathy.

Platelet-Rich Plasma Reduces Retear Rates After Arthroscopic Repair of Small- and Medium-Sized Rotator Cuff Tears but Is Not Cost-Effective

Background: It has been suggested that platelet-rich plasma (PRP) improves healing after arthroscopic rotator cuff repair. The current literature provides ample but inconsistent data on this topic. Purpose: To systematically review the current in vivo evidence for the use of platelet concentrates (PRP) in the arthroscopic treatment of rotator cuff tears to assess effectiveness, safety, and cost-effectiveness. Study Design: Meta-analysis and cost-effectiveness analysis. Methods: Published evidence from controlled, human trials of rotator cuff repair augmented with platelet concentrates was systematically gathered, and data on retear rates were extracted. Mathematical and clinical heterogeneity was evaluated, and fixed-effect meta-analysis was performed to calculate the risk ratio (RR) of retears and the number needed to treat (NNT). Subgroup analyses were made for small/medium tears (n = 404) and large/massive tears (n = 374). Cost-effectiveness was assessed using data from this meta-analysis and using cost data from the literature, including extensive sensitivity analyses, to calculate the incremental cost-effectiveness ratio (ICER). Results: Thirteen studies published between 2010 and 2014 were identified for analysis. The RR for retear for all patients was 0.87 (95% CI, 0.67-1.12; P = .286). For small- and medium-sized tears (<3 cm), the RR for retear was 0.60 (95% CI, 0.37-0.97), consistent with a significant difference in favor of PRP use (P = .038). This translated into an NNT of 14 (95% CI, 7-125). However, at an ICER of US

Rates of Radiolucency and Loosening After Total Shoulder Arthroplasty with Pegged or Keeled Glenoid Components

127,893 per quality-adjusted life year gained, assuming a 5% revision rate, the use of PRP was not cost-effective for small- and medium-sized tears. Conclusion: In large tears, even with double-row repair, the beneficial effects of PRP alone are insufficient to compensate the progressed tissue damage. The study data suggest that PRP may promote healing of small- and medium-sized tears to reduce retear rates. However, despite the substantial biological effect, at current cost, the use of PRP is not cost-effective in arthroscopic repair of small- and medium-sized tears.

Comparison of All-Inside Meniscal Repair Devices With Matched Inside-Out Suture Repair

BACKGROUND The objective of this study was to conduct a meta-analysis and cost-effectiveness analysis of the effect of glenoid design on radiolucency, loosening, and revision after total shoulder arthroplasty. METHODS We conducted a systematic review of PubMed, MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and CINAHL with use of a search for the terms arthroplasty AND shoulder AND (peg OR keel). Data on study design and on the end points of radiolucency, loosening, and revision were extracted independently and in duplicate. Random-effect models were used to calculate the pooled risk ratio and risk difference. The risk difference was used to estimate the number needed to treat (the number of individuals who would have to receive a pegged component to avoid one loosening or revision). RESULTS Eight studies with a total of 1460 patients (mean age, sixty-seven years) were included. The mean study quality was 1.75 points (95% confidence interval [CI], 1.26 to 2.24) on the 3-point modified Jadad scale. There was no significant difference in the risk of any radiolucency (risk ratio, 0.42; 95% CI, 0.12 to 1.42) or in the risk of severe radiolucency (risk ratio, 0.65; 95% CI, 0.23 to 1.82) between pegged and keeled components. The pooled risk ratio for revision was 0.27 (95% CI, 0.08 to 0.88) in favor of pegged components (p = 0.028). At a cost-effectiveness threshold of

Physiological Achilles tendon length and its relation to tibia length.

50,000 per quality-adjusted life year, pegged components can be between

All-Inside Meniscal Repair Devices Compared With Their Matched Inside-Out Vertical Mattress Suture Repair Introducing 10,000 and 100,000 Loading Cycles

2325 and

The effect of simulated scapular winging on glenohumeral joint translations.

40,920 more expensive than keeled components and still be cost-effective. CONCLUSIONS Our study produced evidence that pegged glenoid components were associated with a lower revision risk compared with keeled components. However, the difference was rather small and will therefore be most meaningful to high-volume shoulder arthroplasty centers. Because of the similarity between primary and secondary costs, pegged glenoid designs were more cost-effective than keeled glenoid designs.

Subacromial Spacer Placement for Protection of Rotator Cuff Repair

Background: All-inside meniscal repairs are performed with increasing frequency because of the availability of newly developed devices. A comparison of their biomechanical characteristics may aid physicians in selecting a method of meniscal repair. Hypothesis: All-inside meniscal repairs will be superior to their inside-out controls in response to cyclic loading and load-to-failure testing. Study Design: Controlled laboratory study. Methods: Sixty-six bucket-handle tears in matched porcine menisci were repaired using the Ultra FasT-Fix, Meniscal Cinch, Ultrabraid No. 0, and FiberWire 2-0 sutures. Initial displacement, cyclic loading (100, 300, and 500 cycles), and load-to-failure testing were performed. The displacement, response to cyclic loading, and mode of failure were recorded. The stiffness was calculated. Results: The Meniscal Cinch demonstrated a significantly higher initial displacement than the other methods tested (P = .04). No significant difference was found among the methods in response to cyclic loading. The inside-out FiberWire repair demonstrated the highest load to failure (120.8 ± 23.5 N) and was significantly higher than both the Meniscal Cinch (64.8 ± 24.1 N, P < .001) and the Ultra FasT-Fix (88.3 ± 14.3 N, P = .002). It was not significantly higher than the inside-out Ultrabraid suture repair (98.8 ± 29.2 N). The inside-out FiberWire repair had the highest stiffness (28.7 ± 7.8 N/mm). It was significantly higher than the Meniscal Cinch (18.0 ± 8.8 N/mm, P = .01). The most common mode of failure in all methods was suture failure. Conclusion: An inside-out suture repair affords surgeons the best overall biomechanical characteristics of the devices tested (initial displacement, response to cyclic loading, and load to failure). For an all-inside repair, the Ultra FasT-Fix reproduces the characteristics of its matched inside-out suture repair more closely than the Meniscal Cinch. Clinical Relevance: Inside-out sutures and all-inside devices have similar responses to cyclic loading.

Design and manufacture of a novel system to simulate the biomechanics of basic and pitching shoulder motion

Objective:The optimal intraoperative Achilles tendon length (ATL) adjustment is crucial for the physiological functioning of the musculotendinous unit. To date, the resting ATL and its relation to tibia length (TL) have never been defined in healthy subjects. We thus performed metric measurements of the ATL and TL. Design:Case series. Setting:Clinical and radiological measurements. Participants:Fifty-two subjects placed in a 3-T magnetic resonance imaging with the ankle in neutral position. Main Outcome Measures:Unilateral ATL measured from the calcaneal insertion to the beginning of the medial gastrocnemius muscle, TL measured from the intercondylar eminence to the center of the ankle, and qualitative tendon parameters in T2 sequences and human parameters were noted; results were correlated with age, gender, body height, weight, body mass index (BMI), and side of the AT and TL. Results:The mean ATL was 180.6 ± 25.0 mm and the mean TL was 371.9 ± 25.4 mm with an ATL:TL ratio of 49 ± 5%. Achilles tendon length correlated significantly with body height (R2 = 38%, P < 0.0001) and with TL (R2 = 41%, P < 0.0001) but did not correlate with age, BMI, and side of the AT. Tibia length correlated with body height (R2 = 83%, P < 0.0001) and in multivariate linear regression, TL was the only independent predictor of ATL following the algorithm, ATL (mm) = 0.6 × TL (mm) − 53 (R2 = 41%). Conclusions:We defined a new way to measure the ATL in a consistent way in healthy subjects and showed correlations between ATL, TL and body height and defined an algorithm of ATL based on TL. The ATL and the ATL-algorithm might be important in patients with impaired tendons such as AT ruptures.