Corinne Reid

Maturation of Cognitive Control: Delineating Response Inhibition and Interference Suppression

Cognitive control is integral to the ability to attend to a relevant task whilst suppressing distracting information or inhibiting prepotent responses. The current study examined the development of these two subprocesses by examining electrophysiological indices elicited during each process. Thirteen 18 year-old adults and thirteen children aged 8–11 years (mean = 9.77 years) completed a hybrid Go/Nogo flanker task while continuous EEG data were recorded. The N2 topography for both response inhibition and interference suppression changed with increasing age. The neural activation associated with response inhibition became increasingly frontally distributed with age, and showed decreases of both amplitude and peak latency from childhood to adulthood, possibly due to reduced cognitive demands and myelination respectively occurring during this period. Interestingly, a significant N2 effect was apparent in adults, but not observed in children during trials requiring interference suppression. This could be due to more diffuse activation in children, which would require smaller levels of activation over a larger region of the brain than is reported in adults. Overall, these results provide evidence of distinct maturational processes occurring throughout late childhood and adolescence, highlighting the separability of response inhibition and interference suppression.

Maturation of auditory temporal integration and inhibition assessed with event-related potentials (ERPs)

BackgroundWe examined development of auditory temporal integration and inhibition by assessing electrophysiological responses to tone pairs separated by interstimulus intervals (ISIs) of 25, 50, 100, 200, 400, and 800 ms in 28 children aged 7 to 9 years, and 15 adults.ResultsIn adults a distinct neural response was elicited to tones presented at ISIs of 25 ms or longer, whereas in children this was only seen in response to tones presented at ISIs above 100 ms. In adults, late N1 amplitude was larger for the second tone of the tone pair when separated by ISIs as short as 100 ms, consistent with the perceptual integration of successive stimuli within the temporal window of integration. In contrast, children showed enhanced negativity only when tone pairs were separated by ISIs of 200 ms. In children, the amplitude of the P1 component was attenuated at ISIs below 200 ms, consistent with a refractory process.ConclusionsThese results indicate that adults integrate sequential auditory information into smaller temporal segments than children. These results suggest that there are marked maturational changes from childhood to adulthood in the perceptual processes underpinning the grouping of incoming auditory sensory information, and that electrophysiological measures provide a sensitive, non-invasive method allowing further examination of these changes.

Neural correlates of successful and partial inhibitions in children: an ERP study.

This experiment used event-related potentials (ERPs) to investigate the neural processes underlying the development of response inhibition in a modified version of the go/no-go paradigm [Cragg and Nation [2008] Developmental Science 11(6): 819-827]. N2 and P3 ERP components on correct go trials and partial and successful inhibitions were compared in 7- and 9-year-old children. A larger N2 effect on successful inhibitions was found in 9-year-olds compared to 7-year-olds at fronto-central electrodes. N2 amplitude was positively related to behavioral performance in the 7-year-olds suggesting it may reflect inhibitory processes; however, this relationship was not present in the 9-year-olds. Age differences were also apparent in the go P3, perhaps indicating differences in stimulus processing. The no-go P3 component was larger on successful than partial inhibitions. In contrast, there was no difference in N2 amplitude between partial and successful inhibitions. A significant difference was found in N2 latency however. This suggests that inhibitory processes are similar in both cases but initiated earlier on successful inhibitions. N2 latency was also shorter in 9-year-olds than 7-year-olds supporting an increase in the efficiency of response inhibition with age.

Predictive validity of the N2 and P3 ERP components to executive functioning in children: a latent-variable analysis.

Executive functions (EFs) are commonly theorized to be related yet separable constructs in adults, and specific EFs, such as prepotent response inhibition and working memory, are thought to have clear and distinct neural underpinnings. However, recent evidence suggests that EFs are unitary in children up to about 9 years of age. The aim of the current study was to test the hypothesis that peaks of the event-related potential (ERP) of specific EFs are related to behavioral performance, despite EFs being psychometrically indistinguishable in children. Specifically, N2 difference waveform (associated with cognitive control and response inhibition) and P3b peak (associated with updating of working memory) latent variables were created and entered into confirmatory factor analysis and structural equation models with a unitary executive functioning factor. Children aged 7–9 years (N = 215) completed eight measures of inhibition, working memory, and shifting. A modified flanker task was also completed during which EEG data were recorded. The N2 difference waveform and P3b mean amplitude factors both significantly correlated with (and were predictors of) the executive functioning factor, but the P3b latency factor did not. These results provide evidence of the electrophysiological indices of EFs being observable before the associated behavioral constructs are distinguishable from each other. From this, it is possible that ERPs could be used as a sensitive measure of development in the context of evaluation for neuropsychological interventions.

Therapeutic alliance in videoconferencing psychotherapy: A review

Psychotherapy services are limited in remote and rural areas in Australia and across the globe. Videoconferencing has become well established as a feasible and acceptable mode of psychological treatment delivery. Therapeutic alliance (TA) is an essential factor underlying successful therapy across therapeutic models. In order to determine the state of knowledge regarding TA in psychotherapy via videoconferencing, a literature review was conducted on research studies that formally measured TA as primary, secondary or tertiary outcome measures over the past 23 years. The databases searched were Medline, PsycArticles, PsycINFO, PsycEXTRA and EMBASE. Searching identified 9915 articles that measured satisfaction, acceptability or therapeutic rapport, of which 23 met criteria for the review. Three studies were carried out in Australia, 11 in USA, 4 in Canada, 3 in Scotland and 2 in England. Studies overwhelmingly supported the notion that TA can be developed in psychotherapy by videoconference, with clients rating bond and presence at least equally as strongly as in-person settings across a range of diagnostic groups. Therapists also rated high levels of TA, but often not quite as high as that of their clients early in treatment. The evidence was examined in the context of important aspects of TA, including bond, presence, therapist attitudes and abilities, and client attitudes and beliefs. Barriers and facilitators of alliance were identified. Future studies should include observational measures of bond and presence to supplement self-report.

Auditory Development between 7 and 11 years: An Event-Related Potential (ERP) Study

Background There is considerable uncertainty about the time-course of central auditory maturation. On some indices, children appear to have adult-like competence by school age, whereas for other measures development follows a protracted course. Methodology We studied auditory development using auditory event-related potentials (ERPs) elicited by tones in 105 children on two occasions two years apart. Just over half of the children were 7 years initially and 9 years at follow-up, whereas the remainder were 9 years initially and 11 years at follow-up. We used conventional analysis of peaks in the auditory ERP, independent component analysis, and time-frequency analysis. Principal Findings We demonstrated maturational changes in the auditory ERP between 7 and 11 years, both using conventional peak measurements, and time-frequency analysis. The developmental trajectory was different for temporal vs. fronto-central electrode sites. Temporal electrode sites showed strong lateralisation of responses and no increase of low-frequency phase-resetting with age, whereas responses recorded from fronto-central electrode sites were not lateralised and showed progressive change with age. Fronto-central vs. temporal electrode sites also mapped onto independent components with differently oriented dipole sources in auditory cortex. A global measure of waveform shape proved to be the most effective method for distinguishing age bands. Conclusions/Significance The results supported the idea that different cortical regions mature at different rates. The ICC measure is proposed as the best measure of ‘auditory ERP age’.

Neural indicators of error processing and intraindividual variability in reaction time in 7 and 9 year-olds

Childhood is associated with improvements in task accuracy, response time, and reductions in intraindividual trial-to-trial variability in reaction times. The aims of this study were to investigate neural indicators of error monitoring to better understand the mechanisms underlying these cognitive developments in primary school aged children. Specifically, this study explored the development of error processing in 36 children aged 7 years and 41 children aged 9 years, as indexed by two electrophysiological indices of error processing, the error-related negativity (ERN) and the error positivity (Pe). Notably, the amplitude and latency of the ERN and Pe did not differ significantly between the age groups. However, intraindividual variability in response time (RT) was strongly related to ERN amplitude. These data suggest the utility of comparing neural and behavioral indicators of cognitive performance in children and uniquely highlight the importance of considering intraindividual variability in task performance in studies that explore error processing.

Developmental changes in inspection time: what a difference a year makes

This paper provides a partial replication and extension of a classic longitudinal study by Nettelbeck and Wilson [J. Exp. Child Psychol. 40 (1985) 1] that compared the relative influence of maturation and task experience on developmental changes in inspection time (IT). In the study reported in this paper 226 children aged between 6 and 9 were tested on an IT task in Year 1 and immediately retested to assess the importance of task familiarity. They were also retested 1 year and 2 years later. Counter to Nettelbeck and Wilsons conclusion, analyses of these data comparing the relative difference made by age maturation and by task experience revealed that task experience has a much bigger effect on childrens IT than maturation. The implications of this for wider theoretical interpretations of the relationship between IT and development are discussed.

How Useful Are Indices of Personality Pathology When Assessing Domestic Violence Perpetrators

There has been considerable debate about profiling personality pathology when assessing and treating male perpetrators of domestic violence (DV). This study used the Millon Clinical Multiaxial Inventory (MCMI-III) to explore the severity and diversity of male perpetrator personality pathology and response bias in a group of DV perpetrators being assessed for a treatment program (N = 177). We analyzed the sample using the interpretive guidelines of White and Gondolf (2000); 54% of profiles in our sample fell into categories indicative of a personality disorder, and 37% of the total sample provided profiles indicative of severe personality pathology. These percentages were higher than White and Gondolfs findings but lower than some others. There was considerable diversity of personality pathology as well, supporting the contention that there is no one male DV perpetrator profile. Because of debate concerning the manner of responding on self-report instruments, we paid special attention to response biases in our sample. Twenty-six percent of our sample exaggerated (12%) or minimized (14%) their responses. We also found that response biases on the MCMI-III Modifying Indices were related to self-reported severity of psychopathology. This suggests that assessing severity of psychopathology is inadequate without reference to such biases.

Individual differences in highly skilled visual perceptual-motor striking skill

Expertise studies into visual perceptual-motor skills have mainly focused their investigation upon group comparisons rather than individual comparisons. This study investigated the pick-up of visual information to time weight transfer and bat kinematics within an exemplar group of striking sport experts using an in situ temporal occlusion paradigm. Highly skilled cricket batsmen faced bowlers and attempted to strike delivered balls, whilst their vision was either temporally occluded through occlusion glasses prior to ball bounce or not occluded (control condition). A chronometric analysis was conducted on trials in the occlusion condition to quantify the pick-up of visual information to time biomechanical variables. Results indicated that initiation of weight transfer and bat downswing, as well as bat downswing completion, was significantly different between some individual batsmen. No significant difference was found between individual batsmen for time of weight transfer completion. Unexpectedly, it was found that achievement of the goal to strike delivered balls, that is, the frequency of bat-ball contacts was not significantly different between batsmen. Collectively, the findings indicate that individual differences exist in the coordination pattern of a complex whole body visual perceptual-motor skill, but these different patterns are used to achieve a similar outcome, which is known as motor equivalence.