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Dive into the research topics where Craig R. Lareau is active.

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Featured researches published by Craig R. Lareau.


Journal of The American Academy of Orthopaedic Surgeons | 2014

Plantar and medial heel pain: diagnosis and management.

Craig R. Lareau; Gregory A. Sawyer; Joanne H. Wang; Christopher W. DiGiovanni

Heel pain is commonly encountered in orthopaedic practice. Establishing an accurate diagnosis is critical, but it can be challenging due to the complex regional anatomy. Subacute and chronic plantar and medial heel pain are most frequently the result of repetitive microtrauma or compression of neurologic structures, such as plantar fasciitis, heel pad atrophy, Baxter nerve entrapment, calcaneal stress fracture, and tarsal tunnel syndrome. Most causes of inferior heel pain can be successfully managed nonsurgically. Surgical intervention is reserved for patients who do not respond to nonsurgical measures. Although corticosteroid injections have a role in the management of select diagnoses, they should be used with caution.


Foot and Ankle Surgery | 2015

Does autogenous bone graft work? A logistic regression analysis of data from 159 papers in the foot and ankle literature

Craig R. Lareau; Matthew E. Deren; Rafe Donahue; Christopher W. DiGiovanni

BACKGROUND While autogenous cancellous iliac crest bone graft is the gold standard for foot and ankle surgery, it lacks Level I evidence. Although one third of all graft cases performed in the United States today rely on allograft, some surgeons believe no graft is necessary. We hypothesized that a systematic review of the foot and ankle literature would reveal that (1) autogenous bone graft during foot and ankle arthrodesis would demonstrate healing rates that were superior to the use of either using allograft or no bone graft at all, and (2) these differences would be even more dramatic in patients having risk factors that impair bone healing. To our knowledge, neither of these assessments to date has ever been performed with this body of literature. The goal of this study was to review the use and union rates of bone graft during foot and ankle arthrodesis and determine if autogenous bone graft was superior. METHODS A literature search was performed to include articles between 1959 and 2012 using autograft, allograft, and/or no bone graft for foot and/or ankle arthrodesis. Case reports involving fewer than four patients, investigations failing to incorporate outcome data, those involving orthobiologic augmentation, and those including vascularized graft, xenograft, or pediatric patients were excluded. Recorded search results included patient demographics, comorbidities, pre-operative diagnosis, surgical procedure, bone graft type and indication, union rate, method of fixation, patient satisfaction, all outcome scores, definition of healing/success, and any listed complications including revision. Final data were stratified based upon the type of graft material. RESULTS This search generated 953 related articles, of which 159 studies (5327 patients) met inclusion criteria. The majority (153/159) were retrospective case series. Systematic review demonstrated a trend toward higher union rates for cancellous autograft (OR 1.39, p=0.11), structural autograft (OR 1.52, p=0.09), and cancellous allograft (OR 1.31, p=0.52) relative to no graft material, but none reached statistical significance. Compared to no graft, structural allograft trended toward worse performance (OR 0.62, p=0.17). The overall probability of union was 93.7% for cancellous autograft, 94.2% for structural autograft, 93.3% for cancellous allograft, 91.4% for no graft, and 86.9% for structural allograft. When only comparing the 19 papers that included a no graft arm (91.9% union rate), data revealed the highest union using cancellous autograft (95.1%, OR 1.73, p=0.09) and structural autograft (96.3%, OR 2.33, p=0.06) while only 76% for structural allograft. No significant statistical association existed between union rates and other recorded variables. CONCLUSION Systematic analysis of bone graft use in foot and ankle fusions favors the use of autograft and cancellous allograft for optimized healing rates, although no differences were statistically significant. If we assume that graft material been chosen for more complex procedures having lower anticipated union rates, then these data lend further support to the use of autograft and cancellous allograft. LEVEL OF EVIDENCE Level IV.


Foot and Ankle Surgery | 2014

A biomechanical evaluation of locked plating for distal fibula fractures in an osteoporotic sawbone model

Jason T. Bariteau; Brad D. Blankenhorn; Craig R. Lareau; David Paller; Christopher W. DiGiovanni

BACKGROUND Supination external rotation (SER) injuries are commonly fixed with a one third tubular neutralization plate. This study investigated if a combination locked plate with additional fixation options was biomechanically superior in osteoporotic bone and comminuted fracture models. METHODS Using an osteoporotic and a comminuted Sawbones model, SER injuries were fixed with a lag screw for simple oblique fibula fractures, and either a one third tubular neutralization plate or a locking plate. Samples were tested in stiffness, peak torque, displacement at failure, and torsion fatigue. RESULTS There was no statistically significant difference in biomechanical testing for fractures treated with a lag screw and plate. For comminuted fractures, locked plating demonstrated statistically significant stiffer fixation. CONCLUSION A combination locked plate is biomechanically superior to a standard one third tubular plate in comminuted SER ankle fractures. There was no biomechanical superiority between locked and one third tubular plates when the fracture was amenable to a lag screw.


Foot and Ankle Specialist | 2015

Contribution of the Medial Malleolus to Tibiotalar Joint Contact Characteristics

Craig R. Lareau; Jason T. Bariteau; David Paller; Sarath Koruprolu; Christopher W. DiGiovanni

Background. Isolated medial malleolus fractures are typically treated operatively to minimize the potential for articular incongruity, instability, nonunion, and posttraumatic arthritis. The literature, however, has not clearly demonstrated inferior outcomes with conservative treatment of these injuries. This study measured the effects of medial malleolus fracture and its resultant instability on tibiotalar joint contact characteristics. We hypothesized that restoration of anatomical alignment and stability through fixation would significantly improve contact characteristics. Methods. A Tekscan pressure sensor was inserted and centered over the talar dome in 8 cadaveric foot and ankle specimens. Each specimen was loaded at 700 N in multiple coronal and sagittal plane orientations. After testing fractured samples, the medial malleolus was anatomically fixed before repeat testing. Contact area and pressure were analyzed using a 2-way repeated-measure ANOVA. Results. In treated fractures, contact areas were higher, and mean contact pressures were lower for all positions. These differences were statistically significant in the majority of orientations and approached statistical significance in pure plantarflexion and pure inversion. Decreases in contact area varied from 15.1% to 42.1%, with the most dramatic reductions in positions of hindfoot eversion. Conclusions. These data emphasize the importance of the medial malleolus in maintaining normal tibiotalar contact area and pressure. The average decrease in contact area after simulated medial malleolar fractures was 27.8% (>40% in positions of hindfoot eversion). Such differences become clinically relevant in cases of medial malleolar nonunion or malunion. Therefore, we recommend anatomical reduction and fixation of medial malleolus fractures with any displacement. Level of Evidence: Therapeutic Level V—Cadaveric Study


Foot and Ankle Specialist | 2013

Comparative Study of Scarf and Extended Chevron Osteotomies for Correction of Hallux Valgus

Bryan G. Vopat; Craig R. Lareau; Julie Johnson; Steven E. Reinert; Christopher W. DiGiovanni

Background Scarf and chevron osteotomies are two described treatments for the correction of hallux valgus deformity, but they have traditionally been employed for different levels of severity. We hypothesized that there would be no statistically significant difference between the results of these two treatments. Methods This study is a retrospective review of 70 consecutive patients treated operatively for moderate and severe hallux valgus malalignment. The two groups based on their operative treatment: scarf osteotomy (Group A) and extended chevron osteotomy (Group B). Preoperative and postoperative hallux valgus angle (HVA), intermetatarsal angle and distal metatarsal articular angle (DMAA) were measured at final follow-up. Charts were also assessed to determine the postoperative rate of satisfaction, stiffness, and pain. Results There were no statistically significant differences between Groups A and B with regard to the HVA preoperatively and postoperatively. The DMAA was statistically significantly higher for Group B both preoperatively (p=0.0403) and postoperatively (p<0.0001). The differences in HVA correction and IMA correction were not statistically significant. There were no statistically significant differences with regard to post-operative stiffness, pain, and satisfaction. Discussion The scarf and extended chevron osteotomies are capable of adequately reducing the HVA and IMA in patients with moderate to severe hallux valgus. These two techniques yielded similar patient outcomes in terms of stiffness, pain and satisfaction. Based on these results, we recommend both the scarf and extended chevron osteotomy as acceptable forms of correction for moderate to severe hallux valgus. Levels of Evidence: III, Retrospective Comparative Study


Journal of Bone and Joint Surgery, American Volume | 2014

The Effect of C-Arm Position on Radiation Exposure During Fixation of Pediatric Supracondylar Fractures of the Humerus

Raymond Y. Hsu; Craig R. Lareau; Jeom Soon Kim; Sarath Koruprolu; Christopher T. Born; Jonathan R. Schiller

BACKGROUND Closed reduction and percutaneous pinning of a pediatric supracondylar fracture of the humerus requires operating directly next to the C-arm to hold reduction and perform fixation under direct imaging. This study was designed to compare radiation exposure from two C-arm configurations: with the image intensifier serving as the operating surface, and with a radiolucent hand table serving as the operating surface and the image intensifier positioned above the table. METHODS We used a cadaveric specimen in this study to determine radiation exposure to the operative elbow and to the surgeon at the waist and neck levels during simulated closed reduction and percutaneous pinning of a pediatric supracondylar fracture of the humerus. Radiation exposure measurements were made (1) with the C-arm image intensifier serving as the operating surface, with the emitter positioned above the operative elbow; and (2) with the image intensifier positioned above a hand table, with the emitter below the table. RESULTS When the image intensifier was used as the operating surface, we noted 16% less scatter radiation at the waist level of the surgeon but 53% more neck-level scatter radiation compared with when the hand table was used as the operating surface and the image intensifier was positioned above the table. In terms of direct radiation exposure to the operative elbow, use of the image intensifier as the operating surface resulted in 21% more radiation exposure than from use of the other configuration. The direct radiation exposure was also more than two orders of magnitude greater than the neck and waist-level scatter radiation exposure. CONCLUSIONS Traditionally, there has been concern over increased radiation exposure when the C-arm image intensifier is used as an operating surface, with the emitter above, compared with when the image intensifier is positioned above the operating surface, with the emitter below. We determined that, although there was a statistically significant difference in radiation exposure between the two configurations, neither was safer than the other at all tested levels. CLINICAL RELEVANCE In contrast to traditional teaching regarding radiation exposure, neither C-arm configuration-with the image intensifier serving as the operating surface or with the image intensifier positioned above a radiolucent hand table-was shown to be clearly safer for pediatric supracondylar humeral fracture fixation.


Foot and Ankle Specialist | 2013

Biomechanical Evaluation of Mini-Fragment Hardware for Supination External Rotation Fractures of the Distal Fibula

Jason T. Bariteau; Brad D. Blankenhorn; Craig R. Lareau; David Paller; Christopher W. DiGiovanni

Background. Supination external rotation distal fibula fractures are common, requiring fixation when associated with talar displacement. Subcutaneous distal fibula hardware may become painful, necessitating operative removal. We hypothesize that mini-fragment and small-fragment constructs will demonstrate similar biomechanical stability. Methods. A biomechanical comparison was performed in synthetic osteoporotic sawbones. The first arm compared two 2.4-mm lag screws with one 3.5-mm lag screw for fixation of a simulated supination external rotation distal fibula fracture. The second arm compared a 2.4-mm plate-screw construct with a 3.5-mm lag screw and one-third tubular neutralization plate. During torsional testing, torque and displacement were recorded, and stiffness and peak torque were determined. Results. Differences in mean stiffness and mean load at failure were not statistically significant with lag screw–only fixation. The 3.5-mm plate-screw construct outperformed the 2.4-mm plate-screw construct, but neither mean stiffness nor mean load at failure were statistically significantly different. Dynamic testing also demonstrated similar results. Conclusion. Our data suggest that isolated 2.4-mm screws function similarly to one 3.5-mm screw. Although the 3.5-mm plate-screw construct was stiffer, mean load at failure was equivalent for the 2 constructs. These data provide biomechanical evidence to support further investigation in the use of mini-fragment hardware for distal fibula fracture fixation. Levels of Evidence: Therapeutic, Level V


Orthopedics | 2013

Novel Posterior Splinting Technique to Avoid Heel Ulcers

Raymond Y. Hsu; Craig R. Lareau; Christopher T. Born

Heel ulcers are a costly and preventable complication of lower-extremity immobilization, but they still occur with some regularity. A technique using a short leg posterior splint that suspends the heel away from the splint is described. This modification completely removes pressure the heel to prevent decubitus ulcer formation. This technique is simple, inexpensive, and effective.


Journal of Emergencies, Trauma, and Shock | 2015

Emergency department external fixation for provisional treatment of pilon and unstable ankle fractures

Craig R. Lareau; Alan H. Daniels; Bryan G. Vopat; Patrick M. Kane

Unstable ankle fractures and impacted tibial pilon fractures often benefit from provisional external fixation as a temporizing measure prior to definitive fixation. Benefits of external fixation include improved articular alignment, decreased articular impaction, and soft tissue rest. Uniplanar external fixator placement in the Emergency Department (ED ex-fix) is a reliable and safe technique for achieving ankle reduction and stability while awaiting definitive fixation. This procedure involves placing transverse proximal tibial and calcaneal traction pins and connecting the pins with two external fixator rods. This technique is particularly useful in austere environments or when the operating room is not immediately available. Additionally, this bedside intervention prevents the patient from requiring general anesthesia and may be a cost-effective strategy for decreasing valuable operating time. The ED ex-fix is an especially valuable procedure in busy trauma centers and during mass casualty events, in which resources may be limited.


Alzheimers & Dementia | 2013

Association of unrecognized preoperative cognitive impairment with postoperative cognitive and functional outcomes in elderly people awaiting hip fracture repair

Lori A. Daiello; Alan H. Daniels; Craig R. Lareau; Kathryn Robidoux; Wylie Luo

predictor effects. The severity of bias in parameter estimates may be further exacerbated by the appropriateness of the methodological choices and assumptionsmade for handlingmissing data. The purpose of this study is to perform a comprehensive analysis of the impact of different approaches for handling missing data on the misclassification probabilities of AD diagnosis as a distal outcome.Methods:Using data from individuals diagnosed at baseline as mild cognitively impaired enrolled in 33 Alzheimer’s Disease Centers across the United States, we will conduct a systematic assessment of a) the amount, level, and pattern of missingness in all potential predictors and the outcome of interest (variables are summarized in Table 1), and b) the assumptions about the observed missing data mechanism given the characteristics of the data. Using this information, we will implement five different techniques for handlingmissing data.Wewill apply a variable selectionmethod to reduce dimensionality that selects variables and estimates parameters simultaneously. The overall performance ofmissing data approacheswill be assessed using multiple criteria.Results: At the time of this submission we had completed three of the five proposed missing data approaches. Results show significant differences in the sensitivity and specificity of the prediction model for discriminating converters from non-converters in theMCI group. Further, the choice ofmissing data treatment affects the relative importance of predictors of conversion to AD. Conclusions: Not adjusting for the presence of non-random missing data may lead to biased parameter estimates and inaccurate inferences, reducing the validity of observed causal associations.

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Patrick M. Kane

Thomas Jefferson University

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