Cristina Silveira Moraes Leite

Sunburn, sunscreens, and phenotypes: some risk factors for cutaneous melanoma in southern Brazil

Background The risk factors for cutaneous malignant melanoma have been studied in populations from numerous countries around the world. There are no published studies on the risk factors for this malignancy in Brazil, the largest country in South America.

Prospective study of strongyloidosis in patients with hematologic malignancies

Immunocompromised individuals infected with Strongyloides stercoralis may develop severe hyperinfection or disseminated disease with high mortality. Patients with hematological malignancies are at risk because of immunodepression produced either by the disease or its treatment. A prospective study was undertaken at the Hospital de Clínicas de Porto Alegre, from July 1994 to July 1995. Seventy-two (HIV negative), had 3 stool samples collected at different days and had not received recent anthelmintic therapy. Larvae, isolated in a modified Baermann method, were found in 6 patients, with a resultant prevalence of 8.3%. No complicated strongyloidosis was documented. The positive result for S. stercoralis larvae was significantly associated (p < 0.001) with eosinophilia. Knowledge of prevalence figures and incidence of severe disease is important to adequate guidelines for empirical treatment besides the rigorous search for strongyloidosis in patients with hematological malignancies.

Estudo sobre a associação entre Helicobacter pylori e urticária crônica idiopática

OBJECTIVES: To analise the etiological association of Hp and Idiopathic Chronic Urticaria (UCI). MATERIAL AND METHODS: Case control study. Eighteen patients over 18 years with clinical and laboratory evidences of ICU have been studied. Previous exposure to Hp was evaluated by serum IgG for Hp. The control group, with 18 pacients were paired to age, sex, race and social economic conditions. In the patients positive to Hp oral doses of amoxacilin, metronidazole and omeoprazole were given in order to eradicate the agent. RESULTS: Twelve pacients with UCI were positive to Hp (66,7%) and 6 were positive in the control group (33,3%). In the cases treated to eradicate Hp 6 had complete remission, 4 parcial remission and 2 had no improve. CONCLUSION: There are strong evidences that Hp is an etiological factor of Urticaria. In our study the diference of 33,4% in the previous exposure to Hp between cases and controls and the positive results with the therapeutics confirm the existence of this etiological association.OBJECTIVES To analise the etiological association of Hp and Idiopathic Chronic Urticaria (UCI). MATERIAL AND METHODS Case control study. Eighteen patients over 18 years with clinical and laboratory evidences of ICU have been studied. Previous exposure to Hp was evaluated by serum IgG for Hp. The control group, with 18 patients were paired to age, sex, race and social economic conditions. In the patients positive to Hp oral doses of amoxacilin, metronidazole and omeoprazole were given in order to eradicate the agent. RESULTS Twelve patients with UCI were positive to Hp (66.7%) and 6 were positive in the control group (33.3%). In the cases treated to eradicate Hp 6 had complete remission, 4 parcial remission and 2 had no improve. CONCLUSION There are strong evidences that Hp is an etiological factor of Urticaria. In our study the difference of 33.4% in the previous exposure to Hp between cases and controls and the positive results with the therapeutics confirm the existence of this etiological association.