Curtis E. Jones

Improved Outcomes Via Integrated Molecular Diagnostics and Biofilm Targeted Therapeutics

Molecular diagnostics are validated clinical tools available today for most all clinicians. Given the expanded microbial census they elucidate with DNA-level certainty, a new microbial reality has emerged making interpretation pivotal to advancing outcomes. Regarding chronic infection, there is little consensus for interpretation, even from traditional culture. To advance outcomes, the authors propose an escalating chronic infection protocol leveraging multiple concurrent strategies. A pivotal aspect, directing multiple legs of the protocol, is the diagnostic objectivity and accuracy of molecular diagnostics.