Cynthia W. Tuthill
University of Texas System
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Publication
Featured researches published by Cynthia W. Tuthill.
Aaps Pharmscitech | 2000
Cynthia W. Tuthill; Alfred R. Rudolph; Yang Li; Beijing Tan; Thomas J. Fitzgerald; Stephen R. Beck; Yong-Xi Li
1bstract1 high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS) method was developed to measure the thymosin alpha 1 (Tα1) concentration in human serum. Tα1 in human serum was determined by solid phase extraction and reverse phase LC-MS/MS. The high-performance liquid chromatography (HPLC) system interfaced with the MS/MS system with a Turbo Ion spray interface. Positive ion detection and multiple reaction monitoring (MRM) mode were used for this human serum quantitation. Eight different concentration standards were used to establish the detection range. Six quality control (QC) and 2 matrix blanks were checked by calibration curves performed on the same day. The lower quantitation limit was 0.5 ng/mL T α1 in human serum. Calibration curves were established between 0.5 to 100 ng/mL by weighted linear regression. The correlation coefficients for different days were 0.9955 or greater. Quantitation of Tα1 by the LC-MS/MS method is fast accurate, and precise.
Archive | 2002
Alfred R. Rudolph; Cynthia W. Tuthill
Archive | 2002
Alfred R. Rudolph; Cynthia W. Tuthill
Archive | 2004
Alfred R. Rudolph; Cynthia W. Tuthill
Archive | 2005
Cynthia W. Tuthill; Alfred R. Rudolph; Alexander A. Kolobov; Andrey Simbirtsev; Aleksandr V. Petrov
Archive | 2002
Alfred R. Rudolph; Cynthia W. Tuthill
Archive | 2003
Alfred R. Rudolph; Cynthia W. Tuthill
Archive | 2005
Eric C. Mossel; Cynthia W. Tuthill; Alfred R. Rudolph; Clarence James Peters
Archive | 2006
Cynthia W. Tuthill; Alfred R. Rudolph
Aaps Pharmscitech | 2000
Cynthia W. Tuthill; Alfred R. Rudolph; Yang Yang Li; Beijing Tan; Thomas J. Fitzgerald; Steven R. Beck; Yong-Xi Li
