D. Barry

Four modifiable and other major risk factors for cot death: the New Zealand study.

Abstract New Zealands high mortality rate from sudden infant death syndrome (SIDS) prompted the development of the New Zealand Cot Death Study. A report of the analysis of the data from the first year has been published. This report now gives the major identified risk factors from the full 3 year data set. In this case‐control study there were 485 infants who died from SIDS in the post‐neonatal age group, and 1800 control infants, who were a representative sample of all hospital births in the study region. Obstetric records were examined and parental interviews were completed in 97.5% and 86.9% of subjects, respectively. As expected many risk factors for SIDS were confirmed including: lower socio‐economic status, unmarried mother, young mother, younger school‐leaving age of mother, younger age of mother at first pregnancy, late attendance at antenatal clinic, non‐attendance at antenatal classes, Maori, greater number of previous pregnancies, the further south the domicile, winter, low birthweight, short gestation, male infant and admission to a special care baby unit. In addition, however, we identified four risk factors that are potentially amenable to modification. These were the prone sleeping position of the baby (odds ratio (OR) = 3.70; 95% confidence interval (Cl) = 2.91, 4.70); bed sharing (OR = 2.70; 95% Cl = 2.02, 3.62); maternal smoking of 1–9 cigarettes per day (OR = 3.47; 95% Cl = 2.50, 4.83), 10–19 cigarettes per day (OR = 3.94; 95% Cl = 2.87, 5.41) or more than 20 cigarettes per day (OR = 5.90; 95% Cl = 4.20, 8.31); and not breast feeding (OR = 2.39; 95% Cl = 1.88, 3.04). After controlling for all of the above variables, the relative risks associated with prone sleeping position (OR = 4.84). sharing bed (OR = 2.02), maternal smoking (OR = 1.79) and not breast feeding (OR = 1.89) were still statistically significant. Population‐attributable risk calculations suggest that these four risk factors may account for 82% of deaths from SIDS. The SIDS mortality rate may fall to less than 0.7/1000 live births if all parents stop putting their infants down to sleep in the prone position, do not sleep with their baby, do not smoke, and breast feed their infants.

Fast foods - are they a risk factor for asthma?

Background:  Lifestyle changes over the last 30 years are the most likely explanation for the increase in allergic disease over this period.

Obesity and asthma in 11–12 year old New Zealand children in 1989 and 2000

Background: There has been a concurrent increase in the prevalence of obesity and asthma in recent years in New Zealand and other countries. Methods: Two cross sectional surveys performed in 1989 and 2000 were used to test this association in children of mean age 11.7 years. Body mass index (BMI) was calculated as weight/height2 (kg/m2) and obesity and overweight defined according to an international standard. Standard questions were used to measure the prevalence of asthma symptoms. Results: Significant increases in the prevalence of reported symptoms and disease between 1989 and 2000 were not explained by a concurrent increase in the prevalence of obesity. In 2000, multivariate analysis showed that increasing BMI standard deviation score was significantly associated with current wheeze (p = 0.002), inhaled steroid use (p = 0.004), and the use of any medication (p = 0.001). None of the associations was significantly different for boys or girls. Conclusion: There is some evidence for an association of obesity with asthma symptoms and treatment but this does not explain the increasing prevalence of this disease.

Further evidence supporting a causal relationship between prone sleeping position and SIDS.

Abstract A 3 year case‐control study identifying the risk factors for SIDS was undertaken. Preliminary analysis of the data from the first year suggested that SIDS mortality could fall by 50% if the prevalence of the prone sleeping position changed from 40 to 0%. During the 3 year study the prevalence of the prone sleeping position among infants has fallen from 43% in the first year to 20% in the third year. SIDS mortality has fallen to 3.1/1000 live births, which is very close to that predicted. When considered with other available evidence this strongly supports a causal relationship between the prone sleeping position and SIDS.

Changes in body mass index in 11−12‐year‐old children in Hawkes Bay, New Zealand (1989−2000)

Objective:  To describe and compare the body mass index (BMI; weight/height2) profile of 11−12‐year‐old children in Hawkes Bay, New Zealand in 1989 and 2000. To subsequently determine the prevalence of overweight and obesity at the two time points using international definitions.