D. McGinty

Fragrance material review on phytol

A toxicological and dermatologic review of phytol when used as a fragrance ingredient is presented.

Fragrance material review on α-bisabolol

A toxicologic and dermatologic review of alpha-bisabolol when used as a fragrance ingredient is presented.

Fragrance material review on l-borneol

A toxicologic and dermatologic review of l-borneol when used as a fragrance ingredient is presented.

Addendum to Fragrance material review on Nerolidol (isomer unspecified)

An addendum to the toxicologic and dermatologic review of Nerolidol (isomer unspecified) when used as a fragrance ingredient is presented.

Fragrance material review on 2-ethyl-1-hexanol.

A summary of the safety data available for 2-ethyl-1-hexanol when used as a fragrance ingredient is presented. 2-Ethyl-1-hexanol is a member of the fragrance structural group branched chain saturated alcohols in which the common characteristic structural element is one hydroxyl group per molecule, and a C(4) to C(12) carbon chain with one or several methyl side chains. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. A safety assessment of the entire branched chain saturated alcohol group will be published simultaneously with this document; please refer to Belsito et al. (2010) for an overall assessment of the safe use of this material and all other branched chain saturated alcohols in fragrances.

Fragrance material review on myrtenol

A toxicologic and dermatologic review of myrtenol when used as a fragrance ingredient is presented.

Fragrance material review on terpineol.

A toxicologic and dermatologic review of terpineol when used as a fragrance ingredient is presented.

Fragrance material review on benzyl isobutyrate.

A toxicologic and dermatologic review of benzyl butyrate when used as a fragrance ingredient is presented. Benzyl butyrate is a member of the fragrance structural group Aryl Alkyl Alcohol Simple Acid Esters (AAASAE). The AAASAE fragrance ingredients are prepared by reacting an aryl alkyl alcohol with a simple carboxylic acid (a chain of 1-4 carbons) to generate formate, acetate, propionate, butyrate, isobutyrate and carbonate esters. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for benzyl butyrate were evaluated, then summarized, and includes: physical properties, acute toxicity, skin irritation, skin sensitization, toxicokinetics, and repeated dose data. A safety assessment of the entire AAASAE will be published simultaneously with this document. Please refer to Belsito et al. (2012) for an overall assessment of the safe use of this material and all AAASAE in fragrances.

Fragrance Material Review on isopulegol.

A toxicologic and dermatologic review of isopulegol when used as a fragrance ingredient is presented.

Fragrance material review on benzyl acetate

A toxicologic and dermatologic review of benzyl acetate when used as a fragrance ingredient is presented. Benzyl acetate is a member of the fragrance structural group aryl alkyl alcohol simple acid esters (AAASAE). The AAASAE fragrance ingredients are prepared by reacting an aryl alkyl alcohol with a simple carboxylic acid (a chain of 1-4 carbons) to generate formate, acetate, propionate, butyrate, isobutyrate and carbonate esters. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for benzyl acetate were evaluated, then summarized, and includes: physical properties, acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, elicitation, phototoxicity, toxicokinetics, repeated dose, reproductive toxicity, genotoxicity, or carcinogenicity data. A safety assessment of the entire AAASAE will be published simultaneously with this document. Refer Belsito et al. (2012) for an overall assessment of the safe use of this material and all AAASAE in fragrances.