Dae-Kyung Kim

Successful percutaneous coronary intervention for acute coronary syndrome in a patient with severe hemophilia a.

Patients with hemophilia generally have a reduced frequency of coronary artery disease compared to the general population. As advances in the management of hemophilia have increased their life expectancy, the prevalence of coronary artery disease also has increased. However, there are no standard treatment guidelines for coronary artery disease in patients with hemophilia, especially in the field of coronary intervention. We report the case of a patient with severe hemophilia A who presented with acute coronary syndrome and was successfully treated with percutaneous coronary intervention.

Clinical and Angiographic Outcomes of Drug‐Eluting Stents in Patients With Large Vessel and Single Coronary Artery Lesion

The aim of this study was to evaluate and compare the clinical and angiographic outcomes of 3 drug‐eluting stents (DES) in patients with large vessel diameter and single coronary artery lesions.

868 AMBULATORY BLOOD PRESSURE VARIABILITY AND CAROTID INTIMA-MEDIA THICKNESS IN TREATED HYPERTENSIVE PATIENT

Background: Blood pressure (BP) variability is estimated as the standard deviation (SD) of 24-h ambulatory BP1-3. The present study was performed to determine the effect of the mean day- and night- ambulatory BP values and standard deviations on carotid intima-media thickness (IMT) in treated hypertensive patients4-5. Methods: Carotid IMT and 24-h ambulatory BP were measured in 107 hypertensive patients with treatment (62.6 ± 14.8 years old; clinical systolic/diastolic BP: 144.0/82.3 mmHg). The mean value and SD of ambulatory BP were calculated for the entire 24-h period and separately for the day-time period and the night-time period. Carotid IMT was defined as the distance between the leading edge of the lumen-intima interface and the leading edge of the media-adventitia interface on the far wall, and the greatest IMT value in the bilateral longitudinal projections was recorded as the maximum IMT. Results: Univariate regression analyses revealed a significant association between carotid IMT values and the SD of ambulatory systolic/diastolic BP during night time (r = 0.296, p = 0.004; r = 0.205, p = 0.048, respectively). However, there were no association between carotid IMT and the 24-h systolic/diastolic BP, day-time systolic/diastolic BP, night-time systolic/diastolic BP, the SD of 24-h systolic/diastolic BP, and the SD of day-time systolic/diastolic BP. Multivariate regression analyses confirmed a significant correlation between carotid IMT and the SD of night-time systolic BP (&bgr;=0.232, p = 0.012). Conclusions: In hypertensive patients with treatment, a higher night-time ambulatory systolic BP variability had thicker carotid IMT. Only night-time ambulatory systolic BP variability may be involved in carotid IMT in treated hypertensive patients. ReferencesPickering TG, James GDJ. Ambulatory blood pressure and prognosis. J Hypertens. 1994; 12(Suppl 8): S29–S33.Verdecchia P, Borgioni C, Ciucci A, Gattobigio R, Schillaci G, Sacchi N, et al. Prognostic significance of blood pressure variability in essential hypertension. Blood Press Monit. 1996; 1: 3–11.Kikuya M, Hozawa A, Ohokubo T, Tsuji I, Michimata M, Matsubara M, et al. Prognostic significance of blood pressure and heart rate variabilities: the Ohasama study. Hypertension. 2000; 36: 901–6.Hamada T, Murata T, Narita K, Takahashi T, Wada Y, Kimura H, Yoshida H, et.al. The clinical significance of abnormal diurnal blood pressure variation in healthy late middle-aged and older adults. Blood Press. 2008;17:134-40.

Two-Year Outcomes of theSirolimus-Eluting Stent According toUnprotected Left Main Lesion

The data of long‐term outcomes of sirolimus‐eluting stent (SES) according to lesion location of unprotected left main coronary artery (LMCA) is scarce.

Two-year outcomes of the sirolimus-eluting stent according to unprotected left main lesion.

The data of long‐term outcomes of sirolimus‐eluting stent (SES) according to lesion location of unprotected left main coronary artery (LMCA) is scarce.

PS 05-02 PREVALENCE OF ARTERIAL HYPERTENSION, DIURNAL PATTERN OF BLOOD PRESSURE IN BRANCH RETINAL VEIN OCCLUSION PATIENTS

Objective: To identify in patients with branch retinal vein occlusion using ambulatory blood pressure monitoring and clinical blood pressure measures: hypertension prevalence, and diurnal pattern of blood pressure. Design and Method: Retrospectively, 47 patients with branch retinal vein occlusion were submitted to clinical evaluation and ambulatory blood pressure monitoring. Non-dipper was defined as a fall in systolic blood pressure ⩽ 10%, and dipper when this value was higher. Results: Fifteen (31.9 %) patients were diagnosed as hypertensive after office blood pressure measurement. Ambulatory blood pressure monitoring identified 13 hypertensives, 15 normotensives, 2 white-coat hypertensive and 17 masked hypertensive subjects. Among 13 hypertensive and 17 masked hypertensive subjects, 7 (23.3 %) were dippers and 23 (76.6 %) were non-dippers. Conclusions: Prevalence of masked hypertension in patients with branch retinal vein occlusion was high (64%) and more than two-thirds of hypertensive patients were non-dippers. These evidences suggest that ambulatory blood pressure monitor may be essential examination for patient with branch retinal vein occlusion.