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Dai-Shi Su

Kettering University

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Publication

Featured researches published by Dai-Shi Su.

Angewandte Chemie | 1998

TOTAL SYNTHESES OF CP-225,917 AND CP-263,114 : CREATION OF A MATRIX STRUCTURE BY SEQUENTIAL ALDOL CONDENSATION AND INTRAMOLECULAR HECK RING CLOSURE

Ohyun Kwon; Dai-Shi Su; Dongfang Meng; Wei Deng; Derin C. D'Amico; Samuel J. Danishefsky

Important progress towards the total syntheses of the title compounds, potent inhibitors of squalene synthase and farnesyl transferase, has been accomplished by the construction of the highly functionalized compound 1.

Angewandte Chemie | 1998

Bildung einer Matrixstruktur für die Totalsynthese von CP-225,917 und CP-263,114 durch Aldol- und intramolekulare Heck-Reaktion

Ohyun Kwon; Dai-Shi Su; Dongfang Meng; Wei Deng; Derin C. D'Amico; Samuel J. Danishefsky

Ein entscheidender Schritt auf dem Weg zur Totalsynthese der Titelverbindungen, die die Squalen-Synthase und Farnesyl-Transferase inhibieren, gelang durch den Aufbau der hochfunktionalisierten zentralen Ausgangsverbindung 1.

Angewandte Chemie | 1998

Eine stereospezifische geminale Alkylierung auf dem Weg zu CP‐225,917 und CP‐263,114

Ohyun Kwon; Dai-Shi Su; Dongfang Meng; Wei Deng; Derin C. D'Amico; Samuel J. Danishefsky

Das quartare Stereozentrum an C7 einer Vorstufe der Titelverbindungen konnte durch Addition des von Trost beschriebenen Ylids an 1 aufgebaut werden. Dies und eine Photooxidation, die die Maleinsaureanhydrid-Einheit liefert, sind zwei weitere wichtige Schritte fur die Totalsynthese der beiden Verbindungen.

Angewandte Chemie | 1997

Total Synthesis of (–)‐Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

Dai-Shi Su; Dongfang Meng; Peter Bertinato; Aaron Balog; Erik J. Sorensen; Samuel J. Danishefsky; Yu‐Huang Zheng; Ting-Chao Chou; Lifeng He; Susan Band Horwitz

Archive | 2003

Synthesis of epothilones, intermediates thereto, analogues and uses thereof

Samuel J. Danishefsky; Peter Bertinato; Dai-Shi Su; Dang Fang Meng; Ting-Chao Chou; Theodore M. Kamenecka; Erik J. Sorensen; Aaron Balog; Kenneth Savin

Angewandte Chemie | 1997

Structure–Activity Relationship of the Epothilones and the First In Vivo Comparison with Paclitaxel†

Dai-Shi Su; Aaron Balog; Dongfang Meng; Peter Bertinato; Samuel J. Danishefsky; Yu‐Huang Zheng; Ting-Chao Chou; Lifeng He; Susan Band Horwitz

Angewandte Chemie | 1996

Totalsynthese von (—)‐Epothilon A

Aaron Balog; Dongfang Meng; Theodore M. Kamenecka; Peter Bertinato; Dai-Shi Su; Erik J. Sorensen; Samuel J. Danishefsky

Angewandte Chemie | 1997

Totalsynthese von ( - )-Epothilon B: eine Erweiterung der Suzuki-Kupplung und Erkenntnisse über Struktur-Wirkungs-Beziehungen der Epothilone†

Dai-Shi Su; Dongfang Meng; Peter Bertinato; Aaron Balog; Erik J. Sorensen; Samuel J. Danishefsky; Ting-Chao Chou; Lifeng He; Susan Band Horwitz

Angewandte Chemie | 1998

A Stereospecific Geminal Alkylation Scheme En Route To CP-225, 917 and CP-263,114

Ohyun Kwon; Dai-Shi Su; Dongfang Meng; Wei Deng; Derin C. D'Amico; Samuel J. Danishefsky

Archive | 1997

Synthesis of epothilones, intermediates thereof, analogues and uses thereof

Samuel J. Danishefsky; Aaron Balog; Peter Bertinato; Dai-Shi Su; Ting-Chao Chou; Dong Fang Meng; Theodore M. Kamenecka; Erik J. Sorensen

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Samuel J. Danishefsky

Kettering University

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Dongfang Meng

Kettering University

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Aaron Balog

Kettering University

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Peter Bertinato

Kettering University

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Erik J. Sorensen

Kettering University

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Ting-Chao Chou

Kettering University

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Derin C. D'Amico

Columbia University

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Ohyun Kwon

University of California

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Theodore M. Kamenecka

Scripps Research Institute

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Wei Deng

Kettering University

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