Daisuke Komukai
Showa University
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Daisuke Komukai.
Clinical and Experimental Nephrology | 2011
Yoshinori Sato; Makoto Hirose; Yoshihiko Inoue; Daisuke Komukai; Mamiko Takayasu; Eri Kawashima; Fumihiko Koiwa; Ashio Yoshimura
A 42-year-old female end-stage renal disease (ESRD) patient with reversible posterior leukoencephalopathy syndrome (RPLS) post-transfusion during initiation of hemodialysis is reported. Eleven days after the onset of illness, we diagnosed encephalopathy as a grand mal seizure resulting from diffuse cerebral edema. One reason for the delayed diagnosis was that her symptom, a throbbing headache that occurred during her first dialysis, indicated dialysis disequilibrium syndrome. We must bear in mind that a small amount of transfusion could cause RPLS even during the first dialysis. To our knowledge, this is the first case report on RPLS after blood transfusion in an ESRD patient.
Nephrology | 2016
Daisuke Komukai; Takeshi Hasegawa; Nobuharu Kaneshima; Mamiko Takayasu; Yoshinori Sato; Makoto Hirose; Ashio Yoshimura
Acute kidney injury (AKI) is a common complication of minimal change nephrotic syndrome (MCNS), particularly in adults. We evaluated the prevalence of AKI at the onset of adult MCNS and analyzed the influence of AKI on the duration of achieving complete remission (CR).
Nephron | 2015
Hiroki Nishiwaki; Takeshi Hasegawa; Yoshikuni Nagayama; Nobuharu Kaneshima; Mamiko Takayasu; Makoto Hirose; Daisuke Komukai; Yoshihiko Inoue; Fumihiko Koiwa; Ashio Yoshimura
Introduction and Aims: Deposition of C1q occurs in 0 to 45% of patients with IgAN. In order to identify whether mesangial C1q deposition in IgAN is a novel marker for the response to tonsillectomy plus steroid pulse therapy (TSP), we studied the association between mesangial C1q deposition in IgAN and the remission rate after TSP therapy for IgAN. Methods: We conducted a retrospective cohort study at a single Japanese center. We analyzed data on 110 patients diagnosed with IgA nephropathy who received TSP between January 2003 and December 2012. Positive C1q findings were defined as diffuse mesangial C1q deposition. The study outcome was the resolution of abnormal urinary findings and was defined as negative proteinuria and negative occult blood 1 year after steroid pulse therapy. Results: In all enrolled cases, 69 patients (62.7%) went into remission. Ten out of 24 (41.7%) C1q-positive patients experienced remission, and 59 out of 86 (68.6%) C1q-negative patients experienced remission. Multiple logistic regression model analysis showed that the absence of C1q deposition increased the odds ratio for remission (odds ratio 4.41; 95% confidence interval 1.33-15.75, p = 0.017). Conclusions: These results suggest that the absence of diffuse C1q deposition in the mesangial area of the glomerulus in patients with IgA nephropathy is a positive predictive sign for a response to TSP and is associated with the resolution of urinary abnormalities 1 year after TSP.
Clinical and Experimental Nephrology | 2012
Fumihiko Koiwa; Daisuke Komukai; Makoto Hirose; Ashio Yoshimura; Ryoichi Ando; Toshifumi Sakaguchi; Yasuhiro Komatsu; Toshio Shinoda; Daijo Inaguma; Nobuhiko Joki; Hidemi Nishida; Masato Ikeda; Takashi Shigematsu
Internal Medicine | 2003
Ryuji Suzuki; Hiroyuki Morita; Daisuke Komukai; Takeshi Hasegawa; Naoyuki Nakao; Terukuni Ideura; Ashio Yoshimura
Clinical and Experimental Nephrology | 2015
Yoshikuni Nagayama; Hiroki Nishiwaki; Takeshi Hasegawa; Daisuke Komukai; Eri Kawashima; Mamiko Takayasu; Hironori Tayama; Yoshihiko Inoue; Kiyoko Inui; Ashio Yoshimura
Journal of Infection and Chemotherapy | 2013
Kenji Marumo; Daisuke Komukai; Makoto Hirose; Hisako Nakamura; Hironori Tanaka; Kazuhisa Ugajin; Goro Nagashima; Ashio Yoshimura
Peritoneal Dialysis International | 2009
Takeshi Hasegawa; Ashio Yoshimura; Makoto Hirose; Daisuke Komukai; Hironori Tayama; Susumu Watanabe; Fumihiko Koiwa; Shin Yamazaki; Terukuni Ideura
Nephrology Dialysis Transplantation | 2015
Takeshi Hasegawa; Nobuharu Kaneshima; Hiroki Nishiwaki; Mamiko Takayasu; Daisuke Komukai; Hironori Tayama; Fumihiko Koiwa; Ashio Yoshimura