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Dive into the research topics where Damien Polet is active.

Publication


Featured researches published by Damien Polet.


Chemistry: A European Journal | 2009

Enantioselective Iridium‐Catalyzed Allylic Arylation

Damien Polet; Xavier Rathgeb; Caroline Alexandra Falciola; Jean-Baptiste Langlois; Samir El Hajjaji; Alexandre Alexakis

We describe herein the development of the first iridium-catalyzed allylic substitution using arylzinc nucleophiles. High enantioselectivities were obtained from the reactions, which used commercially available Grignard reagents as the starting materials. This methodology was also shown to be compatible with halogen/metal exchange reactions. Its synthetic potential is demonstrated by its application towards the formal synthesis of (+)-sertraline.


Angewandte Chemie | 2004

A highly effective phosphoramidite ligand for asymmetric allylic substitution.

Karine Tissot-Croset; Damien Polet; Alexandre Alexakis


Chemistry: A European Journal | 2006

Phosphoramidite ligands in iridium-catalyzed allylic substitution

Damien Polet; Alexandre Alexakis; Karine Tissot-Croset; Clémence Corminboeuf; Klaus Ditrich


Journal of Organic Chemistry | 2004

Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc

Alexandre Alexakis; Damien Polet; Stephane Rosset; Sebastien March


Organic Letters | 2004

Very Efficient Phosphoramidite Ligand for Asymmetric Iridium-Catalyzed Allylic Alkylation

Alexandre Alexakis; Damien Polet


Organic Letters | 2005

Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

Damien Polet; Alexandre Alexakis


Chimia | 2006

The copper-catalyzed asymmetric allylic substitution

Alexandre Alexakis; Christophe Malan; Louise Sarah Lea; Karine Tissot-Croset; Damien Polet; Caroline Alexandra Falciola


Organic Letters | 2007

Iridium-catalyzed asymmetric allylic substitution with aryl zinc reagents.

Alexandre Alexakis; Samir El Hajjaji; Damien Polet; Xavier Rathgeb


Tetrahedron Letters | 2005

Cu-catalysed asymmetric 1,4-addition of Me3Al to nitroalkenes. Synthesis of (+)-ibuprofen

Damien Polet; Alexandre Alexakis


Tetrahedron-asymmetry | 2004

Biphenol-based ligands for Cu-catalyzed asymmetric conjugate addition

Alexandre Alexakis; Damien Polet; Cyril Benhaim; Stephane Rosset

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Clémence Corminboeuf

École Polytechnique Fédérale de Lausanne

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