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Dive into the research topics where Daniel C. Cullinane is active.

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Featured researches published by Daniel C. Cullinane.


Surgical Clinics of North America | 2000

HYPOTHERMIA, COAGULOPATHY, AND ACIDOSIS

Virginia A. Eddy; John A. Morris; Daniel C. Cullinane

The management of patients requiring a damage control approach taxes the abilities of the best equipped trauma center. These patients present with severe metabolic abnormalities, most notably characterized by a deadly triad of hypothermia, coagulopathy, and acidosis. Using volumetric, oxymetric pulmonary artery catheters, hypothermia and any ongoing cardiovascular abnormalities can be identified quickly and treatment can be monitored. External, forced air rewarming is a valuable technique in treating the patient with hypothermia, as are more invasive modalities, including body cavity lavage. Although there is no shotgun approach to blood component transfusion therapy, the coagulopathy shown by these patients has a time course that is more rapid than stat laboratories can presently keep up with. Given the fulminant nature of this coagulopathy, the authors feel justified in empirically initiating platelet and plasma or cryoprecipitate transfusion on identification of visible coagulopathy. The willingness of trauma surgeons to push the envelope in treating these most severely afflicted patients has allowed patients who once would have certainly died to lead meaningful lives.


Journal of Trauma-injury Infection and Critical Care | 2010

The management of the open abdomen in trauma and emergency general surgery: part 1-damage control.

Jose J. Diaz; Daniel C. Cullinane; William D. Dutton; Rebecca Jerome; Richard Bagdonas; Jarolslaw O. Bilaniuk; Bryan R. Collier; John J. Como; John Cumming; Maggie Griffen; Oliver L. Gunter; Larry Lottenburg; Nathan T. Mowery; William P. Riordan; Niels D. Martin; Jon Platz; Nicole A. Stassen; Eleanor S. Winston

BACKGROUND The open abdomen technique, after both military and civilian trauma, emergency general or vascular surgery, has been used in some form for the past 30 years. There have been several hundred citations on the indications and the management of the open abdomen. Eastern Association for the Surgery of Trauma practice management committee convened a study group to organize the worlds literature for the management of the open abdomen. This effort was divided into two parts: damage control and the management of the open abdomen. Only damage control is presented in this study. Part 1 is divided into indications for the open abdomen, temporary abdominal closure, staged abdominal repair, and nutrition support of the open abdomen. METHODS A literature review was performed for more than 30 years. Prospective and retrospective studies were included. The reviews and case reports were excluded. Of 1,200 articles, 95 were selected. Seventeen surgeons reviewed the articles with four defined criteria. The Eastern Association for the Surgery of Trauma primer was used to grade the evidence. RESULTS There was only one level I recommendation. A patient with documented abdominal compartment syndrome should undergo decompressive laparotomy. CONCLUSION The open abdomen technique remains a heroic maneuver in the care of the critically ill trauma or surgical patient. For the best outcomes, a protocol for the indications, temporary abdominal closure, staged abdominal reconstruction, and nutrition support should be in place.


Journal of Trauma-injury Infection and Critical Care | 2008

Guidelines for Management of Small Bowel Obstruction

Jose J. Diaz; Faran Bokhari; Nathan T. Mowery; José A. Acosta; Ernest F. J. Block; William J. Bromberg; Bryan R. Collier; Daniel C. Cullinane; Kevin M. Dwyer; Margaret M. Griffen; John C. Mayberry; Rebecca Jerome

STATEMENT OF THE PROBLEMThe description of patients presenting with small bowel obstruction (SBO) dates back to the third or fourth century, when early surgeons created enterocutaneous fistulas to relieve a bowel obstruction. Despite this success with operative therapy, the nonoperative management o


Injury-international Journal of The Care of The Injured | 2001

Needle thoracostomy may not be indicated in the trauma patient

Daniel C. Cullinane; John A. Morris; John G. Bass; Edmund J. Rutherford

OBJECTIVE The aim of this study was to evaluate the usefulness of needle thoracostomy catheter (NTC) placement in trauma. METHODS A consecutive case series was conducted from November 1996 to September 1997. All patients admitted to a level I trauma centre who had NTCs placed prior to arrival in the Emergency Department were included. No patients were excluded or omitted. During the course of the study 2801 patients were admitted to our trauma centre. Nineteen patients (0.68%) had NTCs placed prior to arrival in the emergency department. RESULTS Twenty-five needle thoracostomies were performed in 19 patients. This group represented 0.68% of the trauma admissions. Four patients were found to have evidence of a pneumothorax with an air leak (28%). The NTC failed to decompress the chest in one of two patients who had physiologic evidence of a tension pneumothorax. Eleven patients (58%) were endotracheally intubated prior to NTC. CONCLUSIONS This study suggests that field NTC placements are often ineffective and may be over-used. Further study on the usefulness of NTC is required.


Journal of Trauma-injury Infection and Critical Care | 2011

Eastern Association for the Surgery of Trauma: A Review of the Management of the Open Abdomen-Part 2 "Management of the Open Abdomen"

Jose J. Diaz; William D. Dutton; Mickey M. Ott; Daniel C. Cullinane; Reginald Alouidor; Scott B. Armen; Jaroslaw W. Bilanuik; Bryan R. Collier; Oliver L. Gunter; Randeep S. Jawa; Rebecca Jerome; Andrew J. Kerwin; Anne L. Lambert; William P. Riordan; Christopher D. Wohltmann

During the course of the last 30 years, several authors have contributed their clinical experience to the literature in an effort to describe the various management strategies for the appropriate use of the open abdomen technique. There remains a great degree of heterogeneity in the patient population, and the surgical techniques described. The open abdomen technique has been used in both military and civilian trauma and vascular and general surgery emergencies. Given the lack of consistent practice, the Eastern Association for the Surgery of Trauma (EAST) Practice Management Guidelines Committee convened a study group to establish recommendations for the use of open abdomen techniques in both trauma and nontrauma surgery. This has been a major undertaking and has been divided into two parts. The EAST practice management guidelines for the open abdomen part 1 “Damage Control” have been published.1 During the development of the open abdomen part II “Management of the Open Abdomen,” the current literature remains contentious at best, current methods of treatment continue to change rapidly, and patient populations are so heterogeneous that clear recommendations could not be provided. What follows is a thorough review of the current literature for the management of the open abdomen: part 2 “Management of the Open Abdomen” and provides clinical direction regarding the following specific topics.


Journal of Trauma-injury Infection and Critical Care | 2015

Cervical spine collar clearance in the obtunded adult blunt trauma patient: A systematic review and practice management guideline from the Eastern Association for the Surgery of Trauma

Mayur B. Patel; Stephen S. Humble; Daniel C. Cullinane; Matthew Day; Randeep S. Jawa; Clinton J. Devin; Margaret S. Delozier; Lou M. Smith; Miya A. Smith; Jeannette M. Capella; Andrea M. Long; Joseph S. Cheng; Taylor C. Leath; Yngve Falck-Ytter; Elliott R. Haut; John J. Como

BACKGROUND With the use of the framework advocated by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group, our aims were to perform a systematic review and to develop evidence-based recommendations that may be used to answer the following PICO [Population, Intervention, Comparator, Outcomes] question: In the obtunded adult blunt trauma patient, should cervical collar removal be performed after a negative high-quality cervical spine (C-spine) computed tomography (CT) result alone or after a negative high-quality C-spine CT result combined with adjunct imaging, to reduce peri-clearance events, such as new neurologic change, unstable C-spine injury, stable C-spine injury, need for post-clearance imaging, false-negative CT imaging result on re-review, pressure ulcers, and time to cervical collar clearance? METHODS Our protocol was registered with the PROSPERO international prospective register of systematic reviews on August 23, 2013 (Registration Number: CRD42013005461). Eligibility criteria consisted of adult blunt trauma patients 16 years or older, who underwent C-spine CT with axial thickness of less than 3 mm and who were obtunded using any definition. Quantitative synthesis via meta-analysis was not possible because of pre-post, partial-cohort, quasi-experimental study design limitations and the consequential incomplete diagnostic accuracy data. RESULTS Of five articles with a total follow-up of 1,017 included subjects, none reported new neurologic changes (paraplegia or quadriplegia) after cervical collar removal. There is a worst-case 9% (161 of 1,718 subjects in 11 studies) cumulative literature incidence of stable injuries and a 91% negative predictive value of no injury, after coupling a negative high-quality C-spine CT result with 1.5-T magnetic resonance imaging, upright x-rays, flexion-extension CT, and/or clinical follow-up. Similarly, there is a best-case 0% (0 of 1,718 subjects in 11 studies) cumulative literature incidence of unstable injuries after negative initial imaging result with a high-quality C-spine CT. CONCLUSION In obtunded adult blunt trauma patients, we conditionally recommend cervical collar removal after a negative high-quality C-spine CT scan result alone. LEVEL OF EVIDENCE Systematic review, level III.


American Journal of Surgery | 1998

The futility of chest roentgenograms following routine central venous line changes

Daniel C. Cullinane; David E. Parkus; V. Sreenath Reddy; Nunn Cr; Edmund J. Rutherford

OBJECTIVE To demonstrate chest roentgenograms after central venous line changes over a guidewire delay the use of the central lines and increases charges with no change of morbidity or the rate of complication. METHODS Retrospective study using the Surgical Intensive Care database followed by a nonrandomized, prospective study of central venous line changes. The total time from the catheter change until chest radiograph confirmation and an analysis of charges was done. RESULTS The retrospective study of 1,201 central line changes demonstrated no pneumothorax and two central lines malpositioned. The prospective study of 100 patients demonstrated no pneumothorax and one catheter malpositioned. The average time from completion of the central line change until the radiographic confirmation was 60.2 minutes. The charge for the chest x-ray film was


Journal of Trauma-injury Infection and Critical Care | 2000

Anterior ischemic optic neuropathy: a complication after systemic inflammatory response syndrome.

Daniel C. Cullinane; Judith M. Jenkins; Sreenath Reddy; Timothy VanNatta; Virginia A. Eddy; John G. Bass; Ashton Chen; Mark Schwartz; Patrick Lavin; John A. Morris

156. CONCLUSIONS The combined studies composed of 1,301 patients demonstrated no pneumothorax and three malpositioned catheters. This study demonstrates that radiographic confirmation of central venous line placement after routine line change is of no benefit as the malpositioned catheters caused no morbidity, produces significant delays and increases medical charges to the patient. Extrapolation predicts an annual reduction of


Journal of The American College of Surgeons | 2014

Operative vs nonoperative management for blunt pancreatic transection in children: multi-institutional outcomes.

Corey W. Iqbal; Shawn D. St. Peter; KuoJen Tsao; Daniel C. Cullinane; David M. Gourlay; Todd A. Ponsky; Mark L. Wulkan; Obinna O. Adibe

46,800 in the Vanderbilt Surgical Intensive Care Unit.


Journal of Trauma-injury Infection and Critical Care | 2013

Eastern Association for the Surgery of Trauma: management of the open abdomen, part III-review of abdominal wall reconstruction.

Jose J. Diaz; Daniel C. Cullinane; Kosar Khwaja; G. Hart Tyson; Mickey Ott; Rebecca Jerome; Andrew J. Kerwin; Bryan R. Collier; Peter A. Pappas; Ayodele T. Sangosanya; John J. Como; Faran Bokhari; Elliott R. Haut; Lou M. Smith; Eleanor S. Winston; Jaroslaw W. Bilaniuk; Cynthia L. Talley; Ronald P. Silverman; Martin A. Croce

BACKGROUND Patients are surviving previously fatal injuries. Unique morbidities are occurring in these survivors. Anterior ischemic optic neuropathy represents a previously unrecognized cause of blindness in the trauma victim. We hypothesize that this phenomenon is caused by unique characteristics of optic edema/ pressure or decreased blood flow associated with massive resuscitation. METHODS Between November of 1991 and August of 1998, there were 18,199 admissions to our trauma center. Of this group, 350 patients required massive volume resuscitation (>20 liters infused over first 24 hours). Patients having closed head injuries, facial fractures or direct orbital trauma were excluded from study. The following variables were studied: demographics, injury severity (Injury Severity Score, highest lactate, worst base deficit, and lowest pH) crystalloid and transfusion requirements, ventilator requirements (PEEP) RESULTS: Of the 350 patients with massive resuscitation, 9 patients were diagnosed with anterior ischemic optic neuropathy (2.6%). Of these, seven patients required celiotomy (78%). Six of the seven celiotomy patients had damage control celiotomies and abdominal compartment syndrome (86%). One patient had a repair of a subclavian artery; one had a complex acetabular repair. Blindness was unilateral in five patients and bilateral in four. All nine patients had evidence of global hypoperfusion, systemic inflammatory response, massive resuscitation, and high ventilatory support; one patient required cardiopulmonary resuscitation. CONCLUSION Prone positioning is known to be associated with an increased intraocular pressure. We postulate that the combination of massive resuscitation and prone positioning will increase the incidence of anterior ischemic optic neuropathy. As such, we recommend that prone positioning for adult respiratory distress syndrome be reserved for only those patients at risk of death.

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John A. Morris

Vanderbilt University Medical Center

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Kenji Inaba

University of Southern California

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