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Dive into the research topics where Daniel I. C. Wang is active.

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Featured researches published by Daniel I. C. Wang.


Chemical Engineering Science | 1988

Simultaneous measurement of oxygen diffusion coefficients and solubilities in electrolyte solutions with a polarographic oxygen electrode

Chester S. Ho; Lu-Kwang Ju; Raymond F. Baddour; Daniel I. C. Wang

Abstract The objective of this paper is to present a reliable yet convenient method of measuring simultaneously oxygen diffusion coefficients and solubilities in aqueous electrolyte solutions with a membrane-covered oxygen electrode. Measurements have been conducted in solutions of sodium chloride, potassium chloride, sodium sulfate, and magnesium sulfate over wide ranges of salt concentrations. The experimental results on oxygen diffusion coefficients and solubilities in test electrolyte solutions show an excellent accord with the literature data.


Biotechnology Advances | 1984

Effective diffusivity of oxygen in microbial pellets

Chester S. Ho; Raymond F. Baddour; Daniel I. C. Wang

In a typical submerged aerobic fermentation with microbial pellets, the effective diffusivity of oxygen in the pellets is probably the most important, yet most difficult transport property to characterize experimentally. Its values directly indicate the efficiency or deficiency of oxygen to individual cells, and thus the biological activity of the microorganisms. In the past, it was not possible to assess reliably the effective diffusivity of oxygen in pellets due to several reasons. Firstly, most oxygen electrodes available were coarse, and hence not suitable for in situ measurements. Secondly, there was a lack of methods rigorous enough to characterize the structure of the microbial pellets. A state-of-the-art review of the literature relating to the feature subject is presented. Emphasis is laid upon development and evolution of the means for quantitative characterization of the effective diffusivity of oxygen in microbial pellets.


Animal Cell Bioreactors | 1991

CHAPTER 9 – Hydrodynamic Effects on Animal Cells in Microcarrier Bioreactors

Matthew S. Croughan; Daniel I. C. Wang

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1988.


Biotechnology and Bioengineering | 2000

Hydrodynamic effects on animal cells grown in microcarrier cultures

Matthew S. Croughan; Jean-François P. Hamel; Daniel I. C. Wang


Biotechnology and Bioengineering | 1989

Viscous reduction of turbulent damage in animal cell culture

Matthew S. Croughan; Elizabeth S. Sayre; Daniel I. C. Wang


Biotechnology and Bioengineering | 1989

Growth and death in overagitated microcarrier cell cultures

Matthew S. Croughan; Daniel I. C. Wang


Biotechnology and Bioengineering | 1988

Effects of microcarrier concentration in animal cell culture

Matthew S. Croughan; Jean-François P. Hamel; Daniel I. C. Wang


Archive | 1991

Animal cell bioreactors

Chester S. Ho; Daniel I. C. Wang


Biotechnology (Reading, Mass.) | 1991

Hydrodynamic effects on animal cells in microcarrier bioreactors.

Matthew S. Croughan; Daniel I. C. Wang


Biotechnology and Bioengineering | 1990

Reversible removal and hydrodynamic phenomena in CHO microcarrier cultures

Matthew S. Croughan; Daniel I. C. Wang

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Matthew S. Croughan

Massachusetts Institute of Technology

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Jean-François P. Hamel

Massachusetts Institute of Technology

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Raymond F. Baddour

Massachusetts Institute of Technology

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Elizabeth S. Sayre

Massachusetts Institute of Technology

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