Daniel I. Loube
Walter Reed Army Medical Center
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Daniel I. Loube.
Sleep and Breathing | 1997
Daniel I. Loube; Teotimo Andrada; Natesa Shanmagum; Michael T. Singer
This case report is the first description of the treatment response to an oral appliance (OA) in a patient with upper airway resistance syndrome (UARS). OAs are devices inserted into the mouth in order to modify the position of the mandible and tongue, thus relieving pharyngeal obstruction during sleep in obstructive sleep apnea (OSA) patients. Findings from this case report suggest that an OA may be a useful treatment option for UARS patients.
Sleep and Breathing | 1997
Daniel I. Loube; Milton K. Erman; Walter Reed
BackgroundPerioperative complications in obstructive sleep apnea (OSA) patients are described in a small series of case reports. No study to date systematically evaluates perioperative complications in a large number of OSA patients receiving surgeries other than those involving the pharynx.MethodsNames of the 860 OSA patients seen in a hospital-based sleep disorders center was cross-referenced with a list of the names of the 2,350 patients receiving surgeries in hospital during an 18 month period. In-patient and sleep center records of the 57 OSA patients receiving surgery were reviewed.ResultsNine perioperative complications occurred in eight of 48 OSA patients (17%) receiving general anesthesia. All of these complications were related to difficulties with airway management both pre- and postoperatively. Clinical characteristics including body mass index and Polysomnographie measurements of OSA severity did not prove to be useful predictors of perioperative complications.ConclusionsThe incidence of respiratory complications related to difficulties in airway management in OSA patients was higher than that reported in a recent study for all patients receiving general anesthesia (4%). The perioperative complications observed in these OSA patients are consistent with the underlying pathogenesis of OSA, pharyngeal obstruction. The absence of observed perioperative arrhythmias and myocardial ischemia is consistent with previous findings that sleep-related cardiac ischemia is uncommon in OSA patients. Our results suggest it is prudent to cautiously manage all OSA patients receiving surgeries involving general anesthesia.ZusammenfassungBackgroundKomplikationen vor, während und nach Operationen von Schlafapnoe-patienten sind in einer kleinen Zahl von Fallberichten beschrieben. Bisher gab es keine Studie, die anhand einer großen Zahl von OSA-Patienten systematisch die Komplikationen im Zusammenhang mit chirurgischen Eingriffen außer solchen am Pharynx ausgewertet hätte.MethodenDie Namen von 860 Schlafapnoe-patienten im Zentrum für Schlafstörungen des Krankenhauses wurden im Cross-Reference-Verfahren mit einer Liste von 2350 Patienten verglichen, die innerhalb von 18 Monaten im Krankenhaus operiert worden waren. Die Stationsberichte des Krankenhauses und die Aufzeichnungen des Zentrums für Schlafstörungen von 57 OSA-Patienten, die operiert worden waren, kamen zur Auswertung.Ergebnisse:Bei 8 von 48 OSA-Patienten (17%), die unter Vollnarkose operiert worden waren, hatten sich 9 Komplikationen eingestellt. Alle diese Komplikationen waren mit Atemwegproblemen prä- und postoperativ korreliert. Die klinischen Charakteristiken einschließlich Body-Mass-Index und der poly-somnographischen Bedingungen des Schweregrads des Schlafapnoesyndroms erwiesen sich nicht als nützliche Parameter für die Vorhersage von prä-, intra- oder postoperativen Komplikationen.SchlußfolgerungenDas Vorkommen respiratorischer Komplikationen im Zusammenhang mit Schwierigkeiten der Luftzuführung bei OSA-Patienten war höher, als in einer kürzlichen Studie über Patienten berichtet wurde, die unter Vollnarkose operiert worden waren (4%). Die von uns bei den 8 operierten OSA-Patienten gefundenen Komplikationen stimmen mit der dem obstruktiven Schlafapnoesyndrom zu Grunde liegenden Behinderung überein: der Obstruktion des Pharynx. Es wurden im Zusammenhang mit den Operationen weder Arrhythmien noch Myokardischämien beobachtet, und das steht wiederum im Einklang mit früheren Feststellungen, daß Ischämie des Herzmuskels bei OSA-Patienten höchst ungewöhnlich ist.
Sleep and Breathing | 1999
Daniel I. Loube; Matthew M. McCambridge; Teotimo Andrada
We report on a patient with the onset of recurrent nocturnal awakenings associated with postawakening stridor with onset a few weeks after receiving radiation therapy to the neck. The onset of nocturnal stridor was also accompanied by complaints of snoring and excessive daytime sleepiness. Stridor did not occur during daytime wakefulness. Nocturnal polysomnography (NPSG) recorded with a calibrated pneumotachometer demonstrated snoring and severe obstructive sleep apnea (OSA) with a apnea/hypopnea index of 51 events/hr. One apneic episode persisted for 17 sec after the onset of wakefulness as evidenced by standard NPSG scoring criteria for arousals. With this event, video monitoring revealed the patient abruptly sitting upright and clutching his throat and auditory recording demonstrated stridorous sounds. During wakefulness endoscopy revealed moderate edema and erythema of the supraglottic region, epiglottis, palatine tonsils, and false and true vocal cords. Vocal cord function appeared normal. This case report represents the observation of two rare findings in a single patient, persistence of apnea in wakefulness, and OSA onset following neck irradiation. We review the literature on the persistence of apnea in wakefulness and discuss possible mechanisms for its occurrence in this patient.
Sleep | 2003
Michael R. Littner; Clete A. Kushida; W. McDowell Anderson; Dennis R. Bailey; Richard B. Berry; David Davila; Max Hirshkowitz; Sheldon Kapen; Milton Kramer; Daniel I. Loube; Merrill S. Wise; Stephen F. Johnson
Sleep | 2006
Terri E. Weaver; Daniel I. Loube; Conrad Iber
Chest | 1999
Daniel I. Loube; Kingman P. Strohl; Allan I. Pack; David P. White; Nancy A. Collop
Sleep | 2003
Michael R. Littner; Max Hirshkowitz; Milton Kramer; Sheldon Kapen; W. McDowell Anderson; Dennis R. Bailey; Richard B. Berry; David Davila; Stephen F. Johnson; Clete A. Kushida; Daniel I. Loube; Merrill S. Wise; B. Tucker Woodson
Sleep | 1996
Stuart J. Menn; Daniel I. Loube; Todd D. Morgan; Merrill M. Mitler; Joel S. Berger; Milton K. Erman
Journal of The American Dietetic Association | 1997
Daniel I. Loube; Alicia A. Loube; Milton K. Erman
Chest | 1999
Daniel I. Loube; Teotimo Andrada; Robin S. Howard