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Dive into the research topics where Daniel J. Poon is active.

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Featured researches published by Daniel J. Poon.


Journal of Medicinal Chemistry | 2008

Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors

Savithri Ramurthy; Sharadha Subramanian; Mina Aikawa; Payman Amiri; Abran Costales; Jeff Dove; Susan Fong; Johanna M. Jansen; Barry Levine; Sylvia Ma; Christopher Mcbride; Jonah Michaelian; Teresa Pick; Daniel J. Poon; Sandhya Girish; Cynthia Shafer; Darrin Stuart; Leonard Sung; Paul A. Renhowe

A series of arylaminobenzimidazoles was designed and synthesized as Raf kinase inhibitors. Exploration of the structure-activity relationship resulted in compounds that are potent in vitro and show desirable in vivo properties.


Archive | 2002

Indazole benzimidazole compounds

Paul A. Renhowe; Cynthia Shafer; Christopher Mcbride; Joel B. Silver; Sabina Pecchi; Timothy D. Machajewski; William R. Mccrea; Daniel J. Poon; Teresa Thomas


Bioorganic & Medicinal Chemistry Letters | 2006

4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors

Zhi-Jie Ni; Paul A. Barsanti; Nathan Brammeier; Anthony Diebes; Daniel J. Poon; Simon Ng; Sabina Pecchi; Keith B. Pfister; Paul A. Renhowe; Savithri Ramurthy; Allan S. Wagman; Dirksen E. Bussiere; Vincent P. Le; Yasheen Zhou; Johanna M. Jansen; Sylvia Ma; Thomas G. Gesner


Archive | 2003

Substituted benz-azoles and methods of their use as inhibitors of raf kinase

Paul A. Renhowe; Savithri Ramurthy; Payman Amiri; Barry Levine; Daniel J. Poon; Sharadha Subramanian; Leonard Sung; Wendy J. Fantl; Teresa Hansen; Christopher Mcbride; Cynthia Shafer


Archive | 2004

Substituted benzazoles and methods of their use as inhibitors of raf kinase

Abran Costales; Teresa Hansen; Barry H. Levine; Christopher Mcbride; Daniel J. Poon; Savithri Ramurthy; Paul A. Renhowe; Cynthia Shafer; Sharadha Subramanian; Joelle Verhagen


Archive | 2004

Substituted benzazoles and use thereof as inhibitors of raf kinase

Payman Amiri; Wendy J. Fantl; Barry Levine; Daniel J. Poon; Savithri Ramurthy; Paul A. Renhowe; Sharadha Subramanian; Leonard Sung


Archive | 2012

SUBSTITUTED BENZIMIDAZOLE AND METHOD OF PREPARATION

Dimitroff Martin; マーティン・ディミトロフ; R Miller Bridget; ブリジット・アール・ミラー; Stillwell Brady; ブレイディ・エス・スティルウェル; Dejvid A Sisel; デイビッド・エイ・シーセル; Tajson Suiftni; タイソン・スウィフトニー; Brian Diaz; ブライアン・ディアス; Danlin Gu; ダンリン・グ; Dzhonatan P Van-Dik; ジョナサン・ピー・バン・ディック; Dejvid Rikman; デイビッド・リックマン; Daniel J. Poon; ダニエル ジェイ. プーン,; Teresa E. Pick; テレサ・イー・ピック


Archive | 2011

BENZIMIDAZOLES SUSTITUIDOS COMO INHIBIDORES DE CINASA

Mina Aikawa; Payman Amiri; Jeffrey H. Dove; Barry H. Levine; Christopher Mcbride; Teresa Pick; Savithri Ramurthy; Paul A. Renhowe; Cinthya Shafer; Darrin Stuart; Sharadha Subramanian; Daniel J. Poon


Archive | 2009

Substituierte benzazole und ihre verwendung als raf-kinase-hemmer

Savithri Ramurthy; Sharadha Subramanian; Joelle Verhagen; Daniel J. Poon; Teresa Hansen; Cynthia Shafer; Christopher Mcbride; Barry H. Levine; Abran Costales; Paul A. Renhowe


Archive | 2008

Bencimidazoles sustituidos como inhibidores de quinasa.

Mina Aikawa; Payman Amiri; Jeffrey H. Dove; Barry H. Levine; Christopher Mcbride; Teresa Pick; Daniel J. Poon; Savithri Ramurthy; Paul A. Renhowe; Cynthia Shafer; Darrin Stuart; Sharadha Subramanian

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