Danielle Cabral
Brigham and Women's Hospital
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Journal of General Internal Medicine | 2004
Charles Morris; Danielle Cabral; Hailu Cheng; Jeffrey N. Katz; Joel S. Finkelstein; Jerry Avorn; Daniel H. Solomon
AbstractOBJECTIVES: To identify potential obstacles to bone mineral density (BMD) testing, we performed a structured review of current osteoporosis screening guidelines, studies of BMD testing patterns, and interventions to increase BMD testing. DESIGN: We searched medline and HealthSTAR from 1992 through 2002 using appropriate search terms. Two authors examined all retrieved articles, and relevant studies were reviewed with a structured data abstraction form. MEASUREMENTS AND MAIN RESULTS: A total of 235 articles were identified, and 51 met criteria for review: 24 practice guidelines, 22 studies of screening patterns, and 5 interventions designed to increase BMD rates. Of the practice guidelines, almost one half (47%) lacked a formal description of how they were developed, and recommendations for populations to screen varied widely. Screening frequencies among at-risk patients were low, ranging from 1% to 47%. Only eight studies assessed factors associated with BMD testing. Female patient gender, glucocorticoid dose, and rheumatologist care were positively associated with BMD testing; female physicians, rheumatologists, and physicians caring for more postmenopausal patients were more likely to test patients. Five articles described interventions to increase BMD testing rates, but only two tested for statistical significance and no firm conclusions can be drawn. CONCLUSIONS: This systematic review identified several possible contributors to suboptimal BMD testing rates. Osteoporosis screening guidelines lack uniformity in their development and content. While some patient and physician characteristics were found to be associated with BMD testing, few articles carefully assessed correlates of testing. Almost no interventions to improve BMD testing to screen for osteoporosis have been rigorously evaluated.
Mayo Clinic Proceedings | 2005
Daniel H. Solomon; Charles Morris; Hailu Cheng; Danielle Cabral; Jeffrey N. Katz; Joel S. Finkelstein; Jerry Avorn
OBJECTIVE To assess current osteoporosis treatment guidelines, studies of osteoporosis treatment, and interventions to improve osteoporosis treatment. METHODS We searched the medical literature for articles published between January 1, 1992, and December 31, 2003, and assessed all relevant articles using a structured data abstraction process. Because of substantial heterogeneity in study design, no attempt was made to summarize the data using meta-analytic techniques. RESULTS Seventy-six articles met criteria for inclusion. Eighteen practice guidelines were studied. Most guidelines were consistent in key treatment recommendations. Among 18 studies of treatment rates in patients who had fractures, the weighted average varied from 22% for nonhormonal treatment to 19% for calcium. We found slightly higher treatment rates for patients taking oral glucocorticoids or for those older than 65 years. There were no consistent correlates of which patients received treatment. Six studies that examined treatment frequencies after bone densitometry all found that patients with lower bone mineral density were more likely to receive treatment. Most of the 8 interventions designed to improve osteoporosis treatment showed improvement in treatment rates; however, only 3 were randomized, and these showed the smallest effects. CONCLUSIONS Frequency of treatment of osteoporosis in at-risk populations is low. However, our assessment of the literature revealed no clear and consistent predictors of undertreatment. Few carefully controlled interventions have been reported.
The American Journal of Medicine | 2004
Daniel H. Solomon; M. Alan Brookhart; Tejal K. Gandhi; Andrew S. Karson; Soheyla D. Gharib; E. John Orav; Shimon Shaykevich; Andrea Licari; Danielle Cabral; David W. Bates
Osteoporosis International | 2006
Daniel H. Solomon; Joel S. Finkelstein; Jennifer M. Polinski; Marilyn Arnold; Andrea Licari; Danielle Cabral; Claire Canning; Jerry Avorn; Jeffrey N. Katz
Arthritis Care and Research | 2006
Daniel H. Solomon; Jerry Avorn; Philip S. Wang; George E. Vaillant; Danielle Cabral; Helen Mogun; Til Stürmer
Arthritis Care and Research | 2005
Danielle Cabral; Jeffrey N. Katz; Michael E. Weinblatt; Gladys Ting; Jerry Avorn; Daniel H. Solomon
Arthritis Care and Research | 2006
Daniel H. Solomon; Jeffrey N. Katz; Danielle Cabral; Amanda R. Patrick; Jack F. Bukowski; Jonathan S. Coblyn
The Journal of Rheumatology | 2005
Michele Burgener; Marilyn Arnold; Jeffrey N. Katz; Jennifer M. Polinski; Danielle Cabral; Jerry Avorn; Daniel H. Solomon
The Journal of Rheumatology | 2005
Gladys Ting; Sebastian Schneeweiss; Jeffrey N. Katz; Michael E. Weinblatt; Danielle Cabral; Richard E. Scranton; Daniel H. Solomon
Contemporary Clinical Trials | 2004
Daniel H. Solomon; M. Alan Brookhart; Jennifer M. Polinski; Jeffrey N. Katz; Danielle Cabral; Andrea Licari; Jerry Avorn