Danuta Gajewska

The impact of individualised nutritional therapy according to DASH diet on blood pressure, body mass, and selected biochemical parameters in overweight/obese patients with primary arterial hypertension: a prospective randomised study

BACKGROUND AND AIM The aim of the study was to assess the impact of individualised nutritional intervention based on the DASH diet (Dietary Approaches to Stop Hypertension) on the nutritional status, blood pressure, and selected biochemical parameters of obese/overweight patients with primary arterial hypertension. METHODS A total of 131 participants were randomised to the DASH intervention group (DIG; n = 69, 33 males) or the control group (CG; n = 62, 32 males). A three-month nutritional intervention was carried out in the DIG group, while the control group received only standard recommendations. Body weight, height, waist and hip circumference, body composition, blood pressure, serum glucose, and insulin and leptin concentrations were measured at the baseline and after the intervention. RESULTS Sixty-four (92.8%) participants in the intervention and 62 (100%) in the control group completed the study. In the DIG group a significant decrease in body mass, systolic and diastolic blood pressure, body fat content, fasting glucose, insulin, and leptin concentrations were observed in comparison to the control group (p < 0.05). CONCLUSIONS The DASH dietary intervention provides significant benefits to overweight/obese patients with primary hyper¬tension.

Current prevalence of Helicobacter pylori infection in patients with dyspepsia treated in Warsaw, Poland.

Introduction The prevalence of Helicobacter pylori (Hp) infection in patients with dyspepsia has important clinical and epidemiological implications. However, the current prevalence of Hp infection among patients within Poland is unknown; the last data were collected a decade ago and the majority of previous studies showed the prevalence to be between 60% and 100%. Aim To establish the current prevalence of Hp infection among patients with dyspepsia in Warsaw, Poland. Material and methods The study group comprised 148 patients (126 women and 22 men) with dyspepsia, treated in two outpatient clinics in Warsaw. The mean age in the group that tested positive for Hp was 45.8 years (SD = 14.86; median = 51; min = 19; max = 64). They were tested for Hp infection with a urea breath test that uses 13C-enriched urea and isotope ratio mass spectrometry. Results Helicobacter pylori infection was found in 53 patients (44 women and 9 men), i.e. in 35.8% of the whole study group. We did not find any significant relationship between Hp infection and the patients’ age, gender, or their body mass index. Conclusions The current prevalence of Hp infection among patients with dyspepsia treated in Warsaw is 35.8%. However, our data suggest almost a two-fold fall in the prevalence of Hp infection compared to the previous Polish studies.

The Effectiveness of Dietary Approaches to Stop Hypertension Diet Intervention in Persons with Arterial Hypertension and Obesity: A Key Role of the Patients’ Personality Profile

Background/Aims: Benefits resulting from weight loss and dietary approaches to stop hypertension (DASH) diet in the treatment of arterial hypertension led to a search for a better therapy that would include psychological factors. The present study aimed to assess the relationship between the personality traits included in the Big Five personality traits and the effectiveness of treatment for weight loss in patients with essential hypertension and excessive body weight. Methods: The study involved 84 patients with essential hypertension, overweight or obesity, managed by a hypertensiologist. All patients underwent a 3-month diet treatment as part of the development process of an individualised eating plan that follows the principles of DASH diet and food education. Body mass index and DASH index were calculated before and after the therapy. NEO Five-Factor Inventory was applied to measure psychological variables. Results: The intervention led to a statistically significant increase of DASH index measured before and after treatment. There was a significant correlation between the increase of DASH index and gender. Patients presented higher intensity of openness to experience, extraversion, conscientiousness and lower levels of neuroticism and agreeableness compared to general population. Conclusion: The influence of psychological variables on the observed difference between men and women in DASH values and weight loss was not demonstrated.

Overall Content of Salicylic Acid and Salicylates in Food Available on the European Market

The study aimed to determine the salicylates content in 112 products available on the European market. Quantitative determination of free and conjugated forms of salicylic acid in food was performed using reversed-phase high-performance liquid chromatography with fluorescence detection. The salicylates contents ranged from 0 to 1675.79 (μg/100 g). The results of this study confirm the presence of salicylates in food products, as well as a broad content diversity of these compounds depending on the species, variety, and method of processing the food items. The results can be very helpful for nutritionists and dieticians in planning low-salicylates or high-salicylates diets.