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Featured researches published by Darshan Bb.


Journal of Public Health Research | 2015

Diabetic peripheral neuropathy and its determinants among patients attending a tertiary health care centre in Mangalore, India

Monisha D’Souza; Vaman Kulkarni; Unnikrishnan Bhaskaran; Humam Ahmed; Hegde Naimish; Anjali Prakash; Tabreez S; Bhanu Dahiya; Rekha Thapar; Prasanna Mithra; Nithin Kumar; Ramesh Holla; Darshan Bb; Avinash Kumar

Background The burden of diabetes mellitus (DM) is on the rise especially in developing countries like India. Due to its chronic nature DM tends to cause many debilitating complications and diabetic peripheral neuropathy (DPN) is one of them. The aim of this study is to determine the prevalence of DPN among patients attending a tertiary care hospital and to identify the determinants associated with it. Design and methods A cross sectional study was conducted in Government Wenlock Hospital, Mangalore (India), during January-February 2014. A total of 208 patients with >5 year duration of DM were asked to respond to the patient history version of Michigan Neuropathy Screening Instrument (MNSI) and examinations were conducted after obtaining consent from them. The statistical analysis was done in terms of descriptive statistics and association between variables was tested using logistic regression test. Results The prevalence of DPN using the MNSI history version and MNSI examination were found to be 18.3% and 32.2% respectively. The major determinants associated with DPN were found to be male gender (OR: 2.7, CI: 1.4-5.1, P=0.001), smoking (OR: 5.8, CI: 1.9-17.3, P=0.001) and age >40 years (OR: 2.7, CI: 1.2-5.8, P=0.011). Conclusions The burden of undetected DPN was found to be higher among diabetics, with an especially higher prevalence among males, smokers and those with long standing diabetes mellitus. Interventions in the form of early detection through routine screening, smoking cessation and regular follow up examinations would go a long way in reducing the burden of disability among diabetics and improve their quality of life significantly. Significance for public health The findings of the current research hold importance since diabetes is one of the leading causes of morbidity and mortality across the world. Due to its chronic nature and effects of hyperglycaemia, diabetes tends to be associated with many comorbidities, like peripheral neuropathy, nephropathy, retinopathy etc. The presence of diabetic peripheral neuropathy leads to a reduced quality of life among diabetic patients due to the trauma and consequent gangrenes andamputation. The concept of secondary prevention can be applied to the prevention of diabetic peripheral neuropathy using easy to apply screening tools and thus help in early diagnosis and treatment to reduce the burden of this debilitating illness.


Journal of natural science, biology, and medicine | 2017

Profile of cervical cancer patients attending Tertiary Care Hospitals of Mangalore, Karnataka: A 4 year retrospective study

Aadhya Sharma; Vaman Kulkarni; Unnikrishnan Bhaskaran; Meher Singha; Saad Mujtahedi; Anshul Chatrath; Mallika Sridhar; Rekha Thapar; Prasanna Mithra; Nithin Kumar; Ramesh Holla; Darshan Bb; Avinash Kumar

Objectives: To describe the sociodemographic characteristics and clinical profile of women presenting with cervical carcinoma and to identify factors associated with the timing of presentation and prognosis. Materials and Methods: A record-based descriptive study was carried out from 1st February to 31st March 2014 at Tertiary Care Hospitals of Mangalore. The study population included women who were diagnosed with cervical carcinoma from January 1, 2010 to December 31, 2013. A pretested data extraction sheet aimed at collecting information from the inpatient records was used as the study instrument. The collected data were entered and analyzed using SPSS version 16.0. Results: A total of 227 patients were included in the study. Mean (Standard Deviation) age of diagnosis of cervical cancer was found to be 55 ± 11 years. Majority of the women were Hindus (88.5%) and 51.0% of the women had occupational activities out of which manual labor was the most common. Forty-eight percent of the patients presented in the late stages. Squamous cell carcinoma was found to be the most common histological type. It was also observed that a slightly higher proportion of women with an age >49 years presented in late stages of the disease (n = 70, 48.6%) compared to women <49 years of age (n = 28, 46.7%); however, the difference was not statistically significant (P = 0.800). Conclusions: Our study found out a higher proportion of late presentation by the patients. It emphasizes the need for the development and implementation of an efficient screening cum prevention program for cervical cancer and to continue active research in the domains of identifying all possible risk factors and steps to mitigate them.


African Health Sciences | 2015

Gender preferences among antenatal women: a cross-sectional study from coastal South India.

Nithin K; Kanchan Tanuj; Bhaskaran Unnikrishnan; Rekha T; Mithra Prasanna; Kulkarni Vaman; Holla Ramesh; Darshan Bb; Reddy Samskruthi

BACKGROUND A balanced sex ratio is essential for a stable society. OBJECTIVE The main objective of the present research was to study the perceptions of women attending the antenatal care (ANC) facility regarding their gender preferences and family composition. METHOD In this cross-sectional study 132 antenatal women were interviewed in their preferred language using a predesigned semi-structured questionnaire. The collected information was analyzed using SPSS version 11.5. RESULTS The mean age of the study participants was 27.2 ± 4.1 years. The majority of the antenatal women (60.6%, n=80) did not have any gender preferences. Among those who had a gender preference (39.4%, n=52), male and female preference was reported by 55.7% (n=29) and 44.3% (n=23) of the participants respectively. The overall son preference index was observed to be 1.3. No consistent relationship could be established between the socio-demographic factors and the preference for gender. The mean preferred family size in our study was 1.85±0.531 and more than half of the participants had a balanced gender preference. The majority of the participants were aware that the adverse sex ratio can lead to fall in the number of brides and that it would bring about a social imbalance. CONCLUSION As a developed society we need to ensure that both the genders get equal respect and are free from any sort of preferences and prejudices. To achieve this, more and more people need to be made aware of the consequences of gender imbalance and adverse sex ratio in a society.


Toxicology International | 2015

Clinico‑epidemiological Profile of Snakebite Cases Admitted in a Tertiary Care Centre in South India: A 5 Years Study

Rekha Thapar; Darshan Bb; Bhaskaran Unnikrishnan; Prasanna Mithra; Nithin Kumar; Vaman Kulkarni; Ramesh Holla; Avinash Kumar; Tanuj Kanchan

Objectives: This study was conducted to assess the clinic-epidemiological profile of snakebite cases admitted at a Tertiary Care Centre in South India. Materials and Methods: A record based retrospective study was carried out at Kasturbha Medical College affiliated hospitals in Mangalore. All the snakebite cases admitted to the hospitals from January 2007 to December 2011 were included in the study. Data were collected using a pretested semi-structured questionnaire and analyzed using Statistical Package for Social Sciences (SPSS version 11.5). The results are expressed as percentages. Results: The study included 198 cases of snakebite victims. The majority of the cases were males (68.2%). The mean age of the study population was 34.8 years. Maximum numbers of snakebite cases were reported during the month of September to December (47.9%). The peak time of snakebite was between 18.01 and 24.00 h which was reported in 40.5% of the cases. Lower extremities were the most common site of bite in more than three-fourth of the cases (80.9%). The most common symptoms were a pain (45.9%) and swelling (44.9%). The case fatality rate was observed to be 3.0%. Conclusion: Snakebite still remains a major public health problem in this part of the world. Knowledge must be imparted regarding the prevention of snakebites through community health programs. Messages regarding prompt reporting of such cases and importance of effective treatment must be disseminated among people through mass media and role plays.


Journal of the International Association of Providers of AIDS Care | 2017

HIV-Related Knowledge among PLWHA Attending a Tertiary Care Hospital at Coastal South India—A Facility-Based Study

Arjun Banagi Yathiraj; Bhaskaran Unnikrishnan; John T Ramapuram; Rekha Thapar; Prasanna Mithra; Deepak Madi; Nithin Kumar; Vaman Kulkarni; Ramesh Holla; Jayachidambaram Ambalavanan; Darshan Bb

Background: Adequate knowledge about HIV/AIDS among people living with HIV (PLHIV) is essential for the prevention of HIV transmission. Methods: A cross-sectional study consisting of 409 PLHIV aged ≥18 years were interviewed regarding their HIV-related knowledge, from April 2014 to April 2015. HIV-related knowledge was assessed using the HIV knowledge questionnaire 18 . Univariate and multivariate analyses were done to determine the factors associated with high HIV-related knowledge. Odds ratios with its corresponding 95% confidence intervals were reported. A value of P < .05 was considered to be statistically significant. Results: Among 409 PLHIV, 46.2% had high HIV-related knowledge. Univariate analysis yields factors like upper socioeconomic status, those who are literates, unemployed, and adherent to antiretroviral therapy (ART) were associated with higher HIV-related knowledge. On multivariate analysis, upper socioeconomic status and adherence to ART were the factors that remained significantly associated with higher HIV-related knowledge. Conclusion: HIV-related knowledge among PLHIV can be improved through HIV educational programs.


Journal of the International Association of Providers of AIDS Care | 2016

Factors Influencing Adherence to Antiretroviral Therapy among People Living with HIV in Coastal South India

Arjun Banagi Yathiraj; Bhaskaran Unnikrishnan; John T Ramapuram; Nithin Kumar; Prasanna Mithra; Vaman Kulkarni; Ramesh Holla; Darshan Bb; Rekha Thapar

Background: Antiretroviral Therapy (ART) has transformed life threatening HIV/AIDS scenario into chronic manageable disease. Methodology: In this cross-sectional, 409 People Living with Human Immunodeficiency Virus (PLHIV) aged ≥ 18 years, who were on ART, were assessed regarding the adherence to ART and factors affecting adherence using semi-structured questionnaire. The association between factors affecting adherence and the level of adherence were analyzed using multiple logistic regression model and odds ratio (OR) with 95% confidence intervals (CI) were reported. Results: Among 409 PLHIV, 70.4% showed adherence to ART (≥95%). Univariate analysis yielded many factor associated with adherence (P < 0.05). However, on multivariate analysis, PLHIV who do not forget to take ART and not consuming alcohol were the factors consistent with adherence to ART (P < 0.05). Conclusion: Regular patient education and counseling regarding the usage of memory aids and abstinence from alcohol could be useful for adherence and long term success of ART among PLHIV.


Journal of natural science, biology, and medicine | 2016

Perceptions and knowledge toward mobile-health among the college going students in Coastal South India

Prasanna Mithra Parthaje; Bhaskaran Unnikrishnan; Rekha Thapar; Nithin Kumar; Elizabeth Josy Panikulam; Elina Geroge; Prajwal Pai; Vaman Kulkarni; Ramesh Holla; Darshan Bb; Avinash Kumar; Rohil Mehta; Ratna Jay

Background: Among the manifold uses of mobile phones, mobile-health (mHealth) has been an important one, which is the practice of public health initiatives by awareness raising and communication campaigns. Optimum utilization of mHealth is possible only through adequate awareness. Hence, we aimed to study the perceptions and knowledge about mHealth among college going students in Mangalore, India. Materials and Methods: A cross-sectional study was conducted in March 2014 among 627 students in selected engineering (302 students) and medical colleges (325 students) in Mangalore, India. Colleges were selected using convenience sampling (nonrandom) method. Data were collected using semi-structured self-administered questionnaire and analyzed. Results: Overall, 48.9% were males, 61.4% belonged to 18-20 years age group. The awareness about mobile phone health utilities among medical and engineering students was found to be similar. Among those who were aware of the concept of mHealth (74 [11.2%]), 40 (54.1%) were medical students. Marginally higher proportion of medical students felt mHealth could be helpful in protecting the patients′ confidentiality and would help in better communication with the patients. Conclusion: There was high level of general awareness about mHealth among the subjects. However, many specific areas had limited knowledge among both the streams of students, hence highlighting the need for increasing awareness and sensitization.


Journal of Nutrition and Metabolism | 2018

Snacking Behaviour and Its Determinants among College-Going Students in Coastal South India

Prasanna Mithra; Bhaskaran Unnikrishnan; Rekha Thapar; Nithin Kumar; Sharana Hegde; Anjali Mangaldas Kamat; Vaman Kulkarni; Ramesh Holla; Darshan Bb; Kanchan Tanuj; Vasudev Guddattu; Avinash Kumar

Background Consumption of snacks in between the regular meals is a poor snacking behaviour. It is an established risk factor for several lifestyle-related disorders and has long-term effects among the younger individuals. Objectives To study the snacking behaviour and to assess their determinants among college-going students. Methods This cross-sectional study was conducted among 865 college-going students in Mangaluru. Data were collected using a pretested pro forma that was coded and analyzed using Statistical Package for Social Sciences (SPSS) version 11.5. The chi-square test and random-effect logistic regression analyses were used. Results Overall, there were 52.4% females and 47.6% males, and 76.8% of them were aged <20 years. More than half of the participants (54.3%) had the habit of snacking in between regular meals. Among them, a large proportion (78.7%) did not have any specific timings for snacking. Also, 51.1% of the students were snacking while watching TV, and 31.9% of them snacked while studying. Breakfast was the most commonly skipped meal (26.2%); of those missing the breakfast regularly, 123 (71.9%) had poor snacking behaviour. A significantly larger proportion of males had a higher frequency of snacking per day (69.3% versus 57.2%, p < 0.0001) and consumed aerated drinks more frequently (22.6% versus 15.8%, p=0.011), skipped meals more often (58.6% versus 50.6%, p=0.022), and preferred adding fruits in snacks (78.1% versus 69.4%, p=0.005). Snacking frequency was proportionately higher among students of private colleges (73.6%) than that in the government colleges (55.1%). Participants from nonscience stream, nonvegetarians, and those with a tendency to skip the regular meals had significantly higher levels of poor snacking behaviour. Conclusions The study population had a high level of poor snacking behaviour. Appropriate measures are needed among younger people to follow fixed eating patterns and avoid skipping of regular meals.


Journal of Health Management | 2018

Determinants for Acceptability of a Conditional Cash Transfer Scheme (Janani Suraksha Yojana) for Encouraging Institutional Deliveries among Antenatal Mothers: A Case Control Study

Avinash Kumar; Bhaskaran Unnikrishnan; Rekha T; Prasanna Mithra; Nithin Kumar; Vaman Kulkarni; Ramesh Holla; Darshan Bb; Manognya Chekragari

The objective of this artile is to assess the determinants of acceptance of conditional cash transfer scheme (Janani Suraksha Yojana [JSY]) among antenatal women in Mangalore.The study is on matched case control study. The study has been carried out in the Government maternity hospital of Manipal University and on the antenatal women visiting government hospital for Ante natal care (ANC) and belonged to below poverty line. Total of 136 pregnant females, that is, 68 cases (availing conditional cash benefit) and 68 controls (not availing conditional cash benefit), were recruited in the study. A pretested semi-structured questionnaire was used as data collection tool. The association between the educational status of the participant and their acceptance of JSY and association between the educational status of the participant’s spouse and acceptance of JSY by their wives has been found to be statistically significant. The JSY has been successfully promoting institutional deliveries.


BioMed Research International | 2018

Leptospirosis in Coastal South India: A Facility Based Study

Ramesh Holla; Darshan Bb; Latika Pandey; Bhaskaran Unnikrishnan; Nithin Kumar; Rekha Thapar; Prasanna Mithra; Vaman Kulkarni

Background Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. Objective The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. Methods This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. Results The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. Conclusion High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.

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Nithin Kumar

Kasturba Medical College

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Ramesh Holla

Kasturba Medical College

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Rekha Thapar

Kasturba Medical College

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Vaman Kulkarni

Kasturba Medical College

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Avinash Kumar

Kasturba Medical College

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Kanchan Tanuj

All India Institute of Medical Sciences

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