David F. Mitchell

The Production of Periodontal Disease in the Hamster as Related to Diet, Coprophagy, and Maintenance Factors

IN VIEW of previous studies1 2 it seemed apparent that a prevalent form of experimentally induced periodontal disease in the hamster was associated with one or a combination of the following factors: (1) a high carbohydrate diet of fine consistency; (2) the absence of wood shavings (the presence of which might have aided in the self-cleansing of the teeth and periodontium during mastication or supplied some unknown dietary factor); (3) the inability of animals maintained in wide mesh wire bottom cages to retain their feces and indulge in coprophagy possibly resulting in some dietary deficiency. This study was designed to delineate the effects of these factors and to demonstrate optimal conditions to be employed when it is desired to produce periodontal disease of this type in large numbers of young animals.

Introductory observations of the periodontium of the Syrian hamster.

PERIODONTAL disease has been observed in young hamsters raised on fine caries-producing diets and in older stock animals.1 2 Since hamsters appear to be highly susceptible to periodontal disturbances under certain laboratory conditions, they may prove to be useful experimental animals for the study of this disease. This report is concerned with gross and histological observations of the apparently normal hamster periodontium, and gross and microscopic findings in animals with obvious periodontal disease.

Delivering power with minimal restraint: APL and the web

Networked computers have been used for over 30 years. APL has been part of that environment from the beginning. One key value APL has always provided is the ability for individuals and groups to be independent of complex, centralized administration.Today, APL continues to excel in that role. New technologies often require centralized administration of services such as Web page development and publishing, report printing and distribution, Web based interactive applications and Web enabled data delivery.We have been able to provide these types of services in a way that allows users connected worldwide to a singe APL system to develop, test and distribute data and applications with a minimum of overhead and central control. This paper will discuss four areas of services and several applications in each area.The four areas are:1. Web Mapped APL Files.These allow any user that can create and manage an APL file to create a Web site and distribute non-interactive data.2. Global Print Distribution via FTP.This facility allows any network user to define their PC, Workstation or Server to the APL FTP delivery system. Once defined, reports can be automatically FTPed to their PC from any corporate network host, not just the APL host.3. Parameterized Interactive Web Applications.This is a Web metasystem that allows any APL user to define an interactive Web site using a centralized Web server based in APL. Once the initial registration is complete, the user is free to change or expand their web application using simple, but powerful tools.4. Application-to-Application Systems.These are applications that require custom software on both the server and client systems. These offer the most tailored user interface, but require the most sophisticated programming, in general.