David J. Bjorkman

Risk Factors for

As more patients in the U.S. undergo treatment for Helicobacter pylori infections, antibiotic resistance is emerging and is becoming an important

and Gastric Cancer

Helicobacter pylori infection increases the risk for gastric cancer, one of the most common cancers in the world. Studies designed to examine whether

and Inflammatory Bowel Disease

Some preliminary studies have suggested that patients with Helicobacter pylori infection are less likely to have inflammatory bowel disease (IBD) than

Infection and Gastric Cancer

Gastric cancer is a common cause of death worldwide, but with considerable geographic variation. Part of that variation might be due to differences in

Adjuvant Chemotherapy for Gastric Cancer

Gastric cancer is a major cause of mortality worldwide. Prognosis is poor unless the cancer is diagnosed at a very early stage. In Western countries,

NSAIDs and H. pylori: A Dangerous Combination?

Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs) are independently associated with peptic ulcer disease, but the potential interaction between these factors is controversial. Large, population-based studies have failed to identify a synergistic effect, whereas results from cohort studies suggest both an additive risk and a protective effect associated with H. pylori infection and NSAID use. To examine whether H. pylori eradication reduces ulceration in patients taking NSAIDs, investigators in Hong Kong randomized 100 arthritis patients with H. pylori infection who were about to take NSAIDs for the first time to receive either 1 week of omeprazole-based antibiotic therapy for H. …

Maneuverable Videocapsule Gastroscopy: Not Ready for Prime Time

Capsule endoscopy has been used to evaluate the mucosa of the small and large bowel, but reliance on intrinsic bowel motility has impaired its use in

EMR for Early Gastric Cancer

Endoscopic mucosal resection (EMR) has become standard therapy in Asian countries that have a high incidence of early gastric cancer. Such cancer is

Trends in Gastric Adenocarcinoma

Previous reports suggest that the incidence of gastric cancer is declining in the U.S., perhaps because of a decrease in the prevalence of Helicobacter pylori infection. However, the incidence of noncardia gastric adenocarcinoma has not been well described. In this study, investigators searched the Surveillance, Epidemiology, and End Results (SEER) …

NSAIDs, and Peptic Ulcer Bleeding

Nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the most common causes of peptic ulcer bleeding. In an