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Dive into the research topics where David J. Herzig is active.

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Featured researches published by David J. Herzig.


Journal of Medicinal Chemistry | 1981

Synthesis and antiallergy activity of 4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidines

Francis J. Tinney; Wiaczeslaw Antin Cetenko; Joseph J. Kerbleski; David T. Connor; Roderick J. Sorenson; David J. Herzig

A series of 4-oxo-4H-pyrido[1,2-a]thieno[2,3-d]pyrimidines with substitutions in the 2, 3, and 7 positions was prepared. The compounds were evaluated in the rat passive cutaneous anaphylaxis test for antiallergy activity. Several compounds had potent oral activity and were found to be superior to disodium cromoglycate and doxantrazole. Structure-activity relationships are discussed.


Journal of Medicinal Chemistry | 1981

Pyrazolo[5,1-b]quinazolin-9-ones: a new series of antiallergic agents.

Jagadish C. Sircar; Thomas Capiris; Stephen J. Kesten; David J. Herzig


Journal of Medicinal Chemistry | 1980

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

Paul C. Unangst; Richard E. Brown; David J. Herzig


Journal of Medicinal Chemistry | 1979

11-Oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acid, an orally active antiallergy agent.

Charles F. Schwender; Brooks R. Sunday; David J. Herzig


Journal of Medicinal Chemistry | 1980

Antiallergy activity of 10-oxo-10-H-pyridazino[6,1-b]quinazoline-2-carboxylic acids.

Charles F. Schwender; Brooks R. Sunday; Joseph J. Kerbleski; David J. Herzig


Journal of Medicinal Chemistry | 1979

Antiallergy activity of substituted 11-oxo-11 H-pyrido[2,1-b]quinazoline-8-carboxylic acids.

Charles F. Schwender; Brooks R. Sunday; David J. Herzig; Edward K. Kusner; P. R. Schumann; Daniel L. Gawlak


ChemInform | 1981

SYNTHESIS AND ANTIALLERGY ACTIVITY OF 4‐OXO‐4H‐PYRIDO(1,2‐A)THIENO(2,3‐D)PYRIMIDINES

Francis J. Tinney; Wiaczeslaw Antin Cetenko; Joseph J. Kerbleski; David T. Connor; Roderick J. Sorenson; David J. Herzig


ChemInform | 1981

ANTIALLERGY ACTIVITY OF 10-OXO-10H-PYRIDAZINO(6,1-B)QUINAZOLINE-2-CARBOXYLIC ACIDS

Charles F. Schwender; Brooks R. Sunday; J. J. Kerbleski; David J. Herzig


ChemInform | 1979

Antiallergy activity of substituted 11-oxo-11H-pyrido[2,1-b]quinazoline-8-carboxylic acids

Charles F. Schwender; Brooks R. Sunday; David J. Herzig; Edward K. Kusner; P. R. Schumann; Daniel L. Gawlak


ChemInform | 1981

SYNTHESIS AND ANTIALLERGY ACTIVITY OF 4-OXOPYRANO(3,2-B)INDOLES

P. C. Unangst; R. E. Brown; David J. Herzig

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Richard E. Brown

Michigan Technological University

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