David R. Jones

The orientational phase transition in solid buckminsterfullerene epoxide (C60O)

Abstract Crystalline C 60 O, the first fullerene epoxide, has been studied using calorimetry and high resolution powder X-ray diffraction. At room temperature, C 60 O is orientationally disordered with a face-centered cubic lattice, a = 14.185 A. Upon cooling an orientational ordering transition at 278 K leads to a low temperature simple cubic phase. At 19 K, this phase is qualitatively similar to the orientationally ordered Pa 3 phase of C 60 , with a =14.062 A, but with additional randomness due to a distribution of orientations of the oxygen bonds.

Rationale, development, implementation, and initial results of a fast track protocol for transfemoral transcatheter aortic valve replacement (TAVR)

The care pathway for patients undergoing transcatheter aortic valve replacement (TAVR), particularly in the US, was initially based on open surgical techniques and often includes general anesthesia, transesophageal echocardiographic monitoring, and cardiothoracic intensive care unit (ICU) stays. Whether a subgroup of patients could benefit from early extubation, fewer days in the ICU, and early ambulation in terms of both cost and effectiveness is unknown.

A versatile, efficient synthesis of (−)-(2S, 3R, 4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, the abbott pseudodipeptidyl insert

Abstract An economic construction (6 steps, 36% yield) of a valuable peptide analog subunit, the Abbott pseudodipeplidyl insert (−)-(2 S , 3 R , 4 S )-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane (1), has been developed.