David William Foster

In Vivo Stimulation of Low-Density Lipoprotein Degradation by Insulin

The effect of insulin on low-density lipoprotein (LDL) metabolism in vivo was evaluated using the euglycemic insulin clamp technique. In seven subjects, mononuclear cells isolated after a 4-h insulin infusion degraded more 125I-Iabeled LDL than cells isolated after a saline infusion in six control subjects. In addition, insulin caused the accelerated disappearance of 125I-labeled LDL from plasma in subjects previously injected with autologous 125I-LDL. Infusion of saline had no such effect. These data suggest that insulin, in vivo, stimulates LDL catabolism and could thereby influence LDL cholesterol levels. Insulin-induced stimulation of LDL catabolism could account for the reduction of LDL-cholesterol levels observed in intensively treated type I diabetic patients.

Gay and lesbian themes in Latin American writing

Preface Acknowledgments 1. Introduction 2. Adolfo Caminhas Bom-Crioulo: A Founding Text of Brazilian Gay Literature 3. Vampire Versions of Homosexuality: Seduction and Ruin 4. The Deconstruction of Personal Identity 5. The Sociopolitical Matrix 6. Optical Constructions 7. Narrations on the Self 8. Utopian Designs 9. Conclusions Notes: Translations of Quotations Bibliography Index

Acceleration of Low-Density Lipoprotein Catabolism in Man by Total Parenteral Nutrition

Abstract Since insulin enhances the catabolism of low-density lipoprotein (LDL) by cultured human cells, a potential role of insulin in the regulation of plasma LDL levels in man is suggested. To evaluate the possible effect of insulin on LDL catabolism in vivo, the disappearance rates of injected 125I-labeled autologous LDL were determined before and after endogenous hyperinsulinemia was evoked by total parenteral nutrition. Multicompartmental analysis of plasma decay curves showed a 26% increase in the fractional catabolic rate of LDL after total parenteral nutrition was started. An associated reduction of plasma cholesterol levels resulted from changes in both LDL and high-density lipoprotein. These results suggest that the reduction of LDL levels during total parenteral nutrition is at least partly accounted for by enhanced LDL catabolism. It is postulated that the enhanced LDL catabolism may result from the hyperinsulinemia that accompanies total parenteral nutrition, via insulin stimulation of receptor-mediated LDL catabolism.

The new world border : prophecies, poems & loqueras for the end of the century

Performance texts, poems, and essays explore Americas irrational fears of otherness and hybridization.

Diarios de motocicleta

“Fue una mañana de octubre. Yo había ido a Córdoba aprovechando las vacaciones del 17. Bajo la parra de la casa de Alberto Granado tomábamos mate dulce y comentábamos todas las últimas incidencias de “la perra vida”, mientras nos dedicábamos a la tarea de acondicionar la Poderosa II. Él se lamentaba de haber tenido que abandonar su puesto en el leprosorio de San Francisco de Chañar y del trabajo tan mal remunerado del hospital español. Yo también había tenido que abandonar mi puesto, pero a diferencia de él, estaba muy contento de haberlo dejado; sin embargo, también tenía algunas desazones, debidas, más que nada, a mi espíritu soñador; estaba harto de Facultad de Medicina, de hospitales y de exámenes.

The Oxford companion to Spanish literature

Covers the whole field of literature written in the languages of Spain from Roman times to the present, including the literatures of Latin America alongside those of peninsular Spain (Basque, Catalan, and Galician as well as Castilian).

Effect of L-carnitine treatment on very low density lipoprotein kinetics in the hyperlipidemic rabbit

This study examined the hypolipidemic effect of 4 weeks of L-carnitine treatment (170 mg/kg b.w./day) in New Zealand White rabbits fed a high fat diet (5% corn oil/0.5% cholesterol). Specifically, [3H] glycerol and [125I] very low density lipoprotein (VLDL) turnover studies were conducted to examine the effect of treatment on VLDL kinetics. The masses of plasma VLDL-triglycerides (VLDL-TG) and VLDL-apoprotein B (VLDL-apoB) were significantly increased by the high-fat diet. Four weeks of treatment with L-carnitine significantly reduced these masses. Kinetic analysis indicated that fat feeding reduced the fractional catabolic rates (FCRs) of VLDL-TG and VLDL-apoB relative to chow-fed controls. The transport of these VLDL components was not altered by the diet. L-carnitine treatment had no effect on the FCRs of VLDL-TG and VLDL-apoB or on the transport of VLDL-apoB. Yet, treatment significantly lowered the transport of VLDL-TG. These data indicate that the lipid-lowering effect of L-carnitine in this animal model was due, in part, to a decrease in the transport and not due to an alteration in the fractional catabolic rate of VLDL-TG.

Dictionary of the literature of the Iberian peninsula

Contributions of Iberian-born writers have gone largely unrecognized by most European and American readers. The rich history of literary achievements in the Iberian Penninsula is now available in this unprecedented dictionary. Defining literature in the broad sense, the Dictionary includes historical, religious, cultural and philosophical writings as well as prose, poetry, and drama from the Iberian Peninsula. Virtually all entries have been composed by noted scholars and are complemented wherever possible by bibliographies of primary texts and selected critical studies as well as existing English translations of primary texts. This two-volume work generally includes literature from the tenth century to the mid-1980s and--with a few exceptions--is limited to writers born in the Iberian Peninsula. A guide to determining the format of the Dictionary was the classic Diccionario de Literatura Espanola by German Bleiberg and Julian Marias. But this updated and reworked version devotes more attention to writings by formerly neglected or forgotten works by female authors and to writers in major languages other than Spanish in the peninsula, including Portuguese, Catalan and Galician. There are also entries on major time periods, movements, and other topics. Titles of works discussed are translated to English. Wherever possible, the text of each entry is followed by a three part bibliography; and some cross-referencing. The Dictionary will appeal to English-speaking non-specialists as well as scholars of Iberian literature.

Adolfo Caminha's "Bom-Crioulo": a founding text of brazilian gay literature

It is customary to recognize the early literature of the Republic in Brazil for the brilliant fiction of Machado de Assis, truly the first great nineteenth-century Latin American writer. As befitted Machados identification with the end of the Second Empire and the emerging national bourgeoisie of the Republic, his novels dealt virtually exclusively with genteel society and the various ideologies within which its members defined themselves. In this and other senses, Machados novels are founding texts of the literature of the Republic, texts that provide a necessary point of reference for understanding the society of the period and the ways in which culture interpreted it. Among other founding literary texts of the period, Bom-Crioulo (1895) by Adolfo Caminha (1867-1897) is almost a startling discovery. Although Brazilian literary history takes note of this and the two other novels Caminha published before his untimely death

A TRANSFORMATIONAL ANALYSIS OF SPANISH SE

It is no exaggeration to label se one of the most ubiquitous morphs in the Spanish language.* So multiple and varied are the constructions in which se appears that any simply descriptivist approach cannot hope to reveal the diverse functions which the form has in the production and comprehension of Spanish sentences. The following presentation represents the attempt to examine se within the framework of transformational analysis and to account for its presence in utterances as the realization of different and divergent structural rules.