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Davis L. Temple

Bristol-Myers Squibb

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Publication

Featured researches published by Davis L. Temple.

Progress in Neuro-psychopharmacology & Biological Psychiatry | 1983

Buspirone: An anxioselective alternative for the management of anxiety disorders

Leslie A. Riblet; Arlene S. Eison; Michael S. Eison; R.E. Newton; Duncan P. Taylor; Davis L. Temple

Buspirone HCl (Buspar) is a novel anxiolytic agent unrelated to the benzodiazepines or other psychotherapeutic agents. Animal studies support an anxioselective profile, i.e. relief of anxiety without sedation, muscle relaxation or anticonvulsant activity. Double-blind clinical studies show buspirone to be effective in the treatment of anxiety and anxiety in the presence of depression. The effects of buspirone on psychomotor function, physical dependence and abuse potential tests are similar to those seen with placebo treatments. Mechanism of action studies indicate activity in a variety of neuronal systems.

The American Journal of Medicine | 1986

Buspirone: review of its pharmacology and current perspectives on its mechanism of action

Arlene S. Eison; Davis L. Temple

Journal of Medicinal Chemistry | 1992

Synthesis and biological characterization of .alpha.-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol and analogs as potential atypical antipsychotic agents

Joseph P Yevich; James S. New; Walter G. Lobeck; Pierre Dextraze; Edith Bernstein; Duncan P. Taylor; Frank D. Yocca; Michael S. Eison; Davis L. Temple

Archive | 1985

Method for alleviation of panic disorders

Neil Kurtz; Roger E. Newton; Davis L. Temple

Journal of Medicinal Chemistry | 1983

Buspirone analogues. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives.

Joseph P Yevich; Davis L. Temple; James S. New; Duncan P. Taylor; Leslie A. Riblet

Journal of Medicinal Chemistry | 1988

Atypical antipsychotic agents: patterns of activity in a series of 3-substituted 2-pyridinyl-1-piperazine derivatives.

James S. New; Joseph P Yevich; Davis L. Temple; New Kb; Gross Sm; Schlemmer Rf; Michael S. Eison; Duncan P. Taylor; Leslie A. Riblet

Archive | 1987

Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moieties

Graham S. Poindexter; Davis L. Temple

Archive | 1995

Method for regulation of transmembrane chloride conductance

Valentin K. Gribkoff; Steven I. Dworetzky; Davis L. Temple

Drug Development Research | 1987

Mechanism of acute vasodepressor responses elicited by tiprinast and disodium cromoglycate following intravenous injection in anesthetized dogs

Allen W. Gomoll; Davis L. Temple

Archive | 1985

Topical nonsteroidal anti-inflammatory methods

Xina Nair; Davis L. Temple

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Graham S. Poindexter

Bristol-Myers Squibb

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Neil Kurtz

Bristol-Myers Squibb

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Roger E. Newton

Bristol-Myers Squibb

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Duncan P. Taylor

Bristol-Myers Squibb

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James S. New

Bristol-Myers Squibb

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Joseph P Yevich

Bristol-Myers Squibb

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Leslie A. Riblet

Bristol-Myers Squibb

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Michael S. Eison

Bristol-Myers Squibb

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Xina Nair

Bristol-Myers Squibb

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Arlene S. Eison

Bristol-Myers Squibb

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