Davut Ozdemir
Düzce University
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Davut Ozdemir.
Infection Control and Hospital Epidemiology | 2012
Victor D. Rosenthal; María Eugenia Rodríguez-Calderón; Marena Rodríguez-Ferrer; Tanu Singhal; Mandakini Pawar; Martha Sobreyra-Oropeza; Amina Barkat; Teodora Atencio-Espinoza; Regina Berba; Josephine Anne Navoa-Ng; Lourdes Dueñas; Nejla Ben-Jaballah; Davut Ozdemir; Gulden Ersoz; Canan Aygun
Design. Before-after prospective surveillance study to assess the efficacy of the International Nosocomial Infection Control Consortium (INICC) multidimensional infection control program to reduce the rate of occurrence of ventilator-associated pneumonia (VAP). Setting. Neonatal intensive care units (NICUs) of INICC member hospitals from 15 cities in the following 10 developing countries: Argentina, Colombia, El Salvador, India, Mexico, Morocco, Peru, Philippines, Tunisia, and Turkey. Patients. NICU inpatients. Methods. VAP rates were determined during a first period of active surveillance without the implementation of the multidimensional approach (phase 1) to be then compared with VAP rates after implementation of the INICC multidimensional infection control program (phase 2), which included the following practices: a bundle of infection control interventions, education, outcome surveillance, process surveillance, feedback on VAP rates, and performance feedback on infection control practices. This study was conducted by infection control professionals who applied National Health Safety Network (NHSN) definitions for healthcare-associated infections and INICC surveillance methodology. Results. During phase 1, we recorded 3,153 mechanical ventilation (MV)-days, and during phase 2, after the implementation of the bundle of interventions, we recorded 15,981 MV-days. The VAP rate was 17.8 cases per 1,000 MV-days during phase 1 and 12.0 cases per 1,000 MV-days during phase 2 (relative risk, 0.67 [95% confidence interval, 0.50-0.91]; [Formula: see text]), indicating a 33% reduction in VAP rate. Conclusions. Our results demonstrate that an implementation of the INICC multidimensional infection control program was associated with a significant reduction in VAP rate in NICUs in developing countries.
Annals of Clinical Microbiology and Antimicrobials | 2013
Hakan Leblebicioglu; Recep Ozturk; Victor D. Rosenthal; Özay Arıkan Akan; Fatma Sirmatel; Davut Ozdemir; Cengiz Uzun; Huseyin Turgut; Gulden Ersoz; Iftihar Koksal; A. Ozgultekin; Saban Esen; Fatma Ulger; Ahmet Dilek; Hava Yilmaz; Yalım Dikmen; Gökhan Aygün; Melek Tulunay; Mehmet Oral; Necmettin Ünal; Mustafa Cengiz; Leyla Yilmaz; Mehmet Faruk Geyik; Ahmet Şahin; Selvi Erdogan; Suzan Sacar; Hülya Sungurtekin; Doğaç Uğurcan; Ali Kaya; Necdet Kuyucu
BackgroundCentral line-associated bloodstream infections (CLABs) have long been associated with excess lengths of stay, increased hospital costs and mortality attributable to them. Different studies from developed countries have shown that practice bundles reduce the incidence of CLAB in intensive care units. However, the impact of the bundle strategy has not been systematically analyzed in the adult intensive care unit (ICU) setting in developing countries, such as Turkey. The aim of this study is to analyze the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional infection control approach to reduce the rates of CLAB in 13 ICUs of 13 INICC member hospitals from 8 cities of Turkey.MethodsWe conducted active, prospective surveillance before-after study to determine CLAB rates in a cohort of 4,017 adults hospitalized in ICUs. We applied the definitions of the CDC/NHSN and INICC surveillance methods. The study was divided into baseline and intervention periods. During baseline, active outcome surveillance of CLAB rates was performed. During intervention, the INICC multidimensional approach for CLAB reduction was implemented and included the following measures: 1- bundle of infection control interventions, 2- education, 3- outcome surveillance, 4- process surveillance, 5- feedback of CLAB rates, and 6- performance feedback on infection control practices. CLAB rates obtained in baseline were compared with CLAB rates obtained during intervention.ResultsDuring baseline, 3,129 central line (CL) days were recorded, and during intervention, we recorded 23,463 CL-days. We used random effects Poisson regression to account for clustering of CLAB rates within hospital across time periods. The baseline CLAB rate was 22.7 per 1000 CL days, which was decreased during the intervention period to 12.0 CLABs per 1000 CL days (IRR 0.613; 95% CI 0.43 – 0.87; P 0.007). This amounted to a 39% reduction in the incidence rate of CLAB.ConclusionsThe implementation of multidimensional infection control approach was associated with a significant reduction in the CLAB rates in adult ICUs of Turkey, and thus should be widely implemented.
Mycoses | 2007
Mustafa Y ıld ır ım; Idris Sahin; Abdulkadir Kucukbayrak; Davut Ozdemir; M. Tevfik Yavuz; Sukru Oksuz; Selma Çakır
The hands of healthcare workers (HCWs) are considered to be important for colonisation and infection of Candida spp. The objective of this study was to evaluate the rate of Candida carriage on the hands of the hospital personnel the potential risk factors. Samples were collected from the hands of 214 (139 female and 75 male) hospital personnel working at Duzce Medical Faculty Hospital, Duzce, Turkey. Of these, 88 were nurses, 62 resident doctors, 21 laboratory workers, 30 officers and 13 dining room personnel. The hands of all participants were tested by culture with the broth wash technique. Overall, 34.1% of the people analysed were found to harbour Candida spp. on their hands: 30.7% were nurses, 25.8% resident doctors, 28.6% laboratory workers, 84.6% dining room personnel and 43.3% officers. Candida carriage rates of the dining room personnel were higher than found in the other groups (P = 0.001). Isolated Candida species were C. parapsilosis (38.4%), C. tropicalis (26.0%), C. albicans (23.3%), C. kefyr (11.0%) and C. globosa (1.4%). Candida carriage rate was higher in the glove‐using group (35.1%) than the non‐glove using group (7.1%, P = 0.031). We concluded that carriage of Candida species on the hands of personnel was common especially in non‐medical staff. Wearing gloves was found to be related to increased rates of Candida carriage in the nurse group. Candida parapsilosis was the most frequently colonising species that may be a predisposing condition for nosocomial infections transmitted with the hands of HCWs. Hospital personnel should be educated for regular hand washing practice for preventing Candida colonisation.
Annals of Clinical Microbiology and Antimicrobials | 2014
Hakan Leblebicioglu; Nurettin Erben; Victor D. Rosenthal; Begüm Atasay; Ayse Erbay; Serhat Unal; Gunes Senol; Ayse Willke; A. Ozgultekin; Nilgun Altin; Mehmet Bakir; Oral Oncul; Gulden Ersoz; Davut Ozdemir; Ata Nevzat Yalcin; Halil Özdemir; Dincer Yildizdas; Iftihar Koksal; Canan Aygun; Fatma Sirmatel; Alper Sener; Nazan Tuna; Özay Arıkan Akan; Huseyin Turgut; A Pekcan Demiroz; Tanıl Kendirli; Emine Alp; Cengiz Uzun; Sercan Ulusoy; Dilek Arman
BackgroundDevice-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012.MethodsA DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods.ResultsWe collected prospective data from 94,498 ICU patients for 647,316 bed days. Pooled DA-HAI rates for adult and paediatric ICUs were 11.1 central line-associated bloodstream infections (CLABSIs) per 1000 central line (CL)-days, 21.4 ventilator-associated pneumonias (VAPs) per 1000 mechanical ventilator (MV)-days and 7.5 catheter-associated urinary tract infections (CAUTIs) per 1000 urinary catheter-days. Pooled DA-HAI rates for NICUs were 30 CLABSIs per 1000 CL-days, and 15.8 VAPs per 1000 MV-days. Extra length of stay (LOS) in adult and paediatric ICUs was 19.4 for CLABSI, 8.7 for VAP and 10.1 for CAUTI. Extra LOS in NICUs was 13.1 for patients with CLABSI and 16.2 for patients with VAP. Extra crude mortality was 12% for CLABSI, 19.4% for VAP and 10.5% for CAUTI in ICUs, and 15.4% for CLABSI and 10.5% for VAP in NICUs. Pooled device use (DU) ratios for adult and paediatric ICUs were 0.54 for MV, 0.65 for CL and 0.88 for UC, and 0.12 for MV, and 0.09 for CL in NICUs. The CLABSI rate was 8.5 per 1,000 CL days in the Medical Surgical ICUs included in this study, which is higher than the INICC report rate of 4.9, and more than eight times higher than the NHSN rate of 0.9. Similarly, the VAP and CAUTI rates were higher compared with U.S. NHSN (22.3 vs. 1.1 for VAP; 7.9 vs. 1.2 for CAUTI) and with the INICC report (22.3 vs. 16.5 in VAP; 7.9 vs. 5.3 in CAUTI).ConclusionsDA-HAI rates and DU ratios in our ICUs were higher than those reported in the INICC global report and in the US NHSN report.
American Journal of Infection Control | 2015
Hakan Leblebicioglu; Nurettin Erben; Victor D. Rosenthal; Alper Sener; Cengiz Uzun; Gunes Senol; Gulden Ersoz; Tuna Demirdal; Fazilet Duygu; Ayse Willke; Fatma Sirmatel; Nefise Oztoprak; Iftihar Koksal; Oral Oncul; Yunus Gurbuz; Ertugrul Guclu; Huseyin Turgut; Ata Nevzat Yalcin; Davut Ozdemir; Tanıl Kendirli; Turan Aslan; Saban Esen; Fatma Ulger; Ahmet Dilek; Hava Yilmaz; Mustafa Sunbul; Ilhan Ozgunes; Gaye Usluer; Metin Otkun; Ali Kaya
BACKGROUND Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. METHODS Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs. Surgical procedures (SPs) were classified into 22 types according to International Classification of Diseases, Ninth Revision criteria. RESULTS We recorded 1879 SSIs, associated with 41,563 SPs (4.3%; 95% confidence interval, 4.3-4.7). Among the results, the SSI rate per type of SP compared with rates reported by the INICC and CDC NHSN were 11.9% for ventricular shunt (vs 12.9% vs 5.6%); 5.3% for craniotomy (vs 4.4% vs 2.6%); 4.9% for coronary bypass with chest and donor incision (vs 4.5 vs 2.9); 3.5% for hip prosthesis (vs 2.6% vs 1.3%), and 3.0% for cesarean section (vs 0.7% vs 1.8%). CONCLUSIONS In most of the 22 types of SP analyzed, our SSI rates were higher than the CDC NHSN rates and similar to the INICC rates. This study advances the knowledge of SSI epidemiology in Turkey, allowing the implementation of targeted interventions.
Journal of Infection Prevention | 2015
Hakan Leblebicioglu; Iftihar Koksal; Victor D. Rosenthal; Özay Arıkan Akan; Asu Ozgultekin; Tanıl Kendirli; Nurettin Erben; Ata Nevzat Yalcin; Sercan Ulusoy; Fatma Sirmatel; Davut Ozdemir; Emine Alp; Dincer Yildizdas; Saban Esen; Fatma Ulger; Ahmet Dilek; Hava Yilmaz; Gürdal Yýlmaz; Selçuk Kaya; Hülya Ulusoy; Melek Tulunay; Mehmet Oral; Necmettin Ünal; Güldem Turan; Nur Akgün; Asuman Inan; Erdal Ince; Adem Karbuz; Ergin Çiftçi; Nevin Taşyapar
Aims: To evaluate the effectiveness of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Hand Hygiene Approach in Turkey and analyse predictors of poor hand hygiene compliance. Design: An observational, prospective, interventional, before-and-after study was conducted from August 2003 to August 2011 in 12 intensive care units (ICU) of 12 hospitals in 11 cities. The study was divided into a baseline and a follow-up period and included random 30-minute observations for hand hygiene compliance in ICU. The hand hygiene approach included administrative support, supplies availability, education and training, reminders in the workplace, process surveillance, and performance feedback. Results: We observed 21,145 opportunities for hand hygiene. Overall hand hygiene compliance increased from 28.8% to 91% (95% CI 87.6–93.0, p 0.0001). Multivariate and univariate analyses showed that several variables were significantly associated with poor hand hygiene compliance: males vs. females (39% vs. 48%; 95% CI 0.79–0.84, p 0.0001), ancillary staff vs. physicians (35% vs. 46%, 95% CI 0.73–0.78, p 0.0001), and adult vs. pediatric ICUs (42% vs. 74%, 95% CI 0.54–0.60, p 0.0001). Conclusions: Adherence to hand hygiene was significantly increased with the INICC Hand Hygiene Approach. Specific programmes should be directed to improve hand hygiene in variables found to be predictors of poor hand hygiene compliance.
Indian Journal of Pharmacology | 2015
Ilker Inanc Balkan; Ayse Batirel; Oguz Karabay; Canan Agalar; Serife Akalin; Ozlem Alici; Emine Alp; Fatma Aybala Altay; Nilgun Altin; Ferhat Arslan; Turan Aslan; Nural Bekiroglu; Salih Cesur; Aygul Dogan Celik; Mustafa Dogan; Bulent Durdu; Fazilet Duygu; Aynur Engin; Derya Ozturk Engin; Ibak Gonen; Ertugrul Guclu; Tumer Guven; Cigdem Ataman Hatipoglu; Salih Hosoglu; Mustafa Kasım Karahocagil; Aysegul Ulu Kilic; Bahar Ormen; Davut Ozdemir; Serdar Özer; Nefise Oztoprak
Objectives: To compare the efficacy of colistin (COL) monotherapy versus non-COL based combinations in the treatment of bloodstream infections (BSIs) due to multidrug resistant Acinetobacter spp.(MDR-A). Materials and Methods: Retrospective data of 107 MDR-A BSI cases from 27 tertiary centers in Turkey were included. Primary End-Point: 14-day mortality. Secondary End-Points: Microbial eradication and clinical improvement. Results: Thirty-six patients in the COL monotherapy (CM) group and 71 in the non-COL based combinations (NCC) group were included in the study. Mean age was 59.98 ± 20 years (range: 18–89) and 50.5% were male. Median duration of follow-up was 40 days (range: 9–297). The 14-day survival rates were 52.8% in CM and 47.23% in NCC group (P = 0.36). Microbiological eradication was achieved in 69% of CM and 83% of NCC group (P = 0.13). Treatment failure was detected in 22.9% of cases in both CM and NCC groups. Univariate analysis revealed that mean age (P = 0.001), Charlson comorbidity index (P = 0.03), duration of hospital stay before MDR-A BSI (P = 0.04), Pitt bacteremia score (P = 0.043) and Acute Physiology and Chronic Health Evaluation II score (P = 0.05) were significant in terms of 14-day mortality. Advanced age (P = 0.01) and duration of hospital stay before MDR-A BSI (P = 0.04) were independently associated with 14-day mortality in multivariate analysis. Conclusion: No significant difference was detected between CM and non-COL based combinations in the treatment of MDR-A BSIs in terms of efficacy and 14-day mortality.
Mycoses | 2009
Ertugrul Guclu; Zeki Soypacaci; Mustafa Yildirim; Abdulkadir Kucukbayrak; Davut Ozdemir
Fungal peritonitis is a relatively uncommon complication of peritoneal dialysis that contributes significantly to morbidity, drop out from the continuous ambulatory peritoneal dialysis (CAPD) program, and mortality. Candida sake infections were rarely published in literature. We present the first case of peritonitis due to C. sake. A 41‐year‐old man was admitted to our hospital with abdominal pain, nausea, vomiting, fever, weakness. Abdominal ultrasonography demonstrated a fistula tract, which has an opening at inferolateral of the umbilicus extending 5 cm from the skin into the abdominal cavity with a foreign body (11 × 10 mm length) inside the fistula. The foreign body was removed by surgery being apparently a part of a previously inserted peritoneal catheter. Postoperative specimens revealed polymorph leucocytes and yeast cells in Gram stain, and culture on Sabouraud dextrose agar (SDA) yielded a growth of a fungus, subsequently identified as C. sake with Api ID 32C. Fluconazole (200 mg/day) therapy was started. He recovered after two weeks of therapy. In conclusion, C. sake, a rare type of Candida species, should be considered as a probable peritoneal pathogen in patients with multiple episodes of bacterial peritonitis, previous broad‐spectrum antibiotic therapy and diabetes mellitus.
Neurosurgery Quarterly | 2012
Abdulkadir Kucukbayrak; Keziban Demirli; Davut Ozdemir; Zeynep Seckin Kucukbayrak; Ismail Necati Hakyemez
Sphingomonas paucimobilis is a Gram-negative aerobic rod, which is nonfermentative, nonspore forming, catalase positive, and oxidase positive. It is believed that the natural habitat of this organism is the natural environment, and it is also found in hospital settings. The infections caused by the bacteria are rarely life threatening. A 46-year-old woman was admitted to our clinic with right flank pain, groin pain, and fever. On clinical examination, right costovertebral angle pain and an operation scar in the temporal region were observed. A review of her medical history revealed an operation for subarachnoid hemorrhage secondary to aneurysm and a ventriculoperitoneal shunt 6 weeks before admission. Ceftriaxone 2×1 g/day was started. No growth was detected in urine, cerebrospinal fluid, and temporal fluid cultures; however, a Gram-negative rod grew in one of the blood cultures on the second day of treatment. Intravenous ciprofloxacin 400 mg 2×1/day was added to treatment. Ceftriaxone treatment was switched to cefoperazon-sulbactam 1 gr 2×1/day. No growth was observed in urine and blood control cultures on the third day of treatment. Cefoperazon-sulbactam was stopped on the 10th day, and ciprofloxacin was continued until the 21st day. In English literature, the presence of Sphingomonas paucimobilis bacteremia after neurosurgery has not been previously reported.
Journal of Infection in Developing Countries | 2014
Ertugrul Guclu; Nazan Tuna; Oguz Karabay; Sila Akhan; Hurrem Bodur; Bahadir Ceylan; Tuna Demirdal; Kutbettin Demirdag; Nese Demirturk; Hasan Çetin Ekerbiçer; Serpil Erol; Saban Esen; Ömer Evirgen; Mehmet Faruk Geyik; Alper Gunduz; Mustafa Kasım Karahocagil; Omer Faruk Kokoglu; Davut Ozdemir; Nail Ozgunes; Fatma Sargin; Selma Tosun; Ediz Tütüncü
INTRODUCTION Although pegylated interferons (pegIFNs) alpha-2a and alpha-2b have been used in chronic hepatitis B (CHB) treatment for many years, there are few studies concerning predictors of sustained virologic response (SVR) to pegIFN therapy. In this study, we aimed to investigate the predictors of response to pegIFN treatment in cases with HBeAg-negative CHB infection. METHODOLOGY Seventeen tertiary care hospitals in Turkey were included in this study. Data from consecutively treated HBeAg-negative CHB patients, who received either pegIFN alpha-2a or alpha-2b, were collected retrospectively. SVR is defined as an HBV DNA concentration of less than 2,000 IU/mL six months after the completion of therapy RESULTS SVR was achieved in 40 (25%) of the 160 HBeAg-negative CHB patients. Viral loads in patients with SVR were lower compared to those with no SVR, beginning in the third month of treatment (p < 0.05). The number of cases with a decline of 1 log10 IU/mL in viral load after the first month of treatment and with a serum HBV DNA level under 2,000 IU/mL after the third month of treatment was higher in cases with SVR (p < 0.05). The number of patients who had undetectable HBV DNA levels at week 48 among responders was significantly greater than among post-treatment virological relapsers (p < 0.05). CONCLUSIONS Detection of a 1 log10 decline in serum HBV DNA level at the first month of treatment and a serum HBV DNA level < 2000 IU/mL at the third month of therapy may be predictors of SVR.