Deborah Jean Lee Wong
Ronald Reagan UCLA Medical Center
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Publication
Featured researches published by Deborah Jean Lee Wong.
Annals of Oncology | 2017
Deborah Jean Lee Wong; Jeffrey Gary Schneider; Raid Aljumaily; Michael Korn; Karen A. Autio; Jeffrey R. Infante; Manish R. Patel; Kyriakos P. Papadopoulos; Aung Naing; Nashat Y. Gabrail; Pamela N. Munster; Jonathan W. Goldman; P. Van Vlasselaer; Annie Hung; Gail Linda Brown; Martin Oft; Edward B. Garon
At therapeutic concentrations, AM0010 stimulates the cytotoxicity, survival and proliferation of intratumoral antigen activated CD8+ T cells in pre-clinical cancer models and in patients. AM0010 activates antigen stimulated CD8 T cells while PD-1 inhibits them. This provides the rationale for combining AM0010 and an anti-PD1. AM0010 monotherapy induced durable objective responses in ocular melanoma and renal cell cancer. AM0010 alone or in combination with chemotherapy and anti-PD1 has been well tolerated in this Phase 1 basket trial. Efficacy and Immune Activation with PEGylated human IL-10 (AM0010) in Combination with an anti-PD1 in Advanced NSCLC Update
European Journal of Cancer | 2015
James L. Gulley; Arun Rajan; David R. Spigel; Nicholas Iannotti; Jason Claud Chandler; Deborah Jean Lee Wong; Joseph Leach; William Jeffery Edenfield; Ding Wang; Marcis Bajars; A. Von Heydebreck; Karen Kelly
Journal of Clinical Oncology | 2016
Karen Kelly; Christopher R. Heery; Manish R. Patel; Jeffrey R. Infante; Nicholas Iannotti; Joseph W. Leach; Ding Wang; Jason Claud Chandler; Hendrik-Tobias Arkenau; Matthew H. Taylor; Michael S. Gordon; Deborah Jean Lee Wong; Howard Safran; Howard L. Kaufman; Ulrich Keilholz; Marcis Bajars; Anja von Heydebreck; Isabell Speit; Jean-Marie Cuillerot; James L. Gulley
Journal of Clinical Oncology | 2016
Michael B. Atkins; F. Stephen Hodi; John A. Thompson; David F. McDermott; Wen-Jen Hwu; Donald P. Lawrence; Nancy A. Dawson; Deborah Jean Lee Wong; Shailender Bhatia; Marihella James; Xinxin Shu; Rodolfo F. Perini; Nageatte Ibrahim; Antoni Ribas; Toni K. Choueiri
Journal of Clinical Oncology | 2016
Christophe Le Tourneau; Christopher J. Hoimes; Corrine Zarwan; Deborah Jean Lee Wong; Sebastian Bauer; Martin Wermke; Rainer Claus; Kevin M. Chin; Anja von Heydebreck; Jean-Marie Cuillerot; James L. Gulley
Journal of Clinical Oncology | 2016
Aung Naing; Kyriakos P. Papadopoulos; Jeffrey R. Infante; Deborah Jean Lee Wong; Karen A. Autio; Patrick A. Ott; Gerald S. Falchook; Manish R. Patel; Shubham Pant; Amita Patnaik; John B. Mumm; Melinda Whiteside; Ivan H. Chan; Johanna C. Bendell; Todd Michael Bauer; Filip Janku; Rivka R. Colen; Nizar M. Tannir; Peter Van Vlasselaer; Martin Oft
Journal of Clinical Oncology | 2016
Kyriakos P. Papadopoulos; Aung Naing; Jeffrey R. Infante; Karen A. Autio; Patrick A. Ott; Deborah Jean Lee Wong; Gerald S. Falchook; Manish R. Patel; Shubham Pant; Melinda Whiteside; John B. Mumm; Ivan H. Chan; Johanna C. Bendell; Drew W. Rasco; Kent C. Shih; Milind Javle; Todd Michael Bauer; Rivka R. Colen; Peter Van Vlasselaer; Martin Oft
Journal of Thoracic Oncology | 2018
Edward B. Garon; Deborah Jean Lee Wong; Jeffrey Gary Schneider; Raid Aljumaily; Wolfgang Michael Korn; Jeffrey R. Infante; Manish R. Patel; Karen A. Autio; Kyriakos P. Papadopoulos; Aung Naing; Nashat Y. Gabrail; Pamela N. Munster; Jonathan W. Goldman; Annie Hung; P. Van Vlasselaer; Joseph Leveque; Martin Oft; David R. Spigel
Annals of Oncology | 2017
Aung Naing; Jeffrey R. Infante; Deborah Jean Lee Wong; Michael Korn; Raid Aljumaily; Kyriakos P. Papadopoulos; Karen A. Autio; Shubham Pant; Todd Michael Bauer; Alexandra Drakaki; Naval Daver; Annie Hung; P. Van Vlasselaer; Gail Linda Brown; Martin Oft; Nizar M. Tannir
Annals of Oncology | 2017
J.R. Hecht; Aung Naing; Gerald S. Falchook; Manish R. Patel; Jeffrey R. Infante; Raid Aljumaily; Deborah Jean Lee Wong; Karen A. Autio; Zev A. Wainberg; Milind Javle; Johanna C. Bendell; Shubham Pant; Annie Hung; P. Van Vlasselaer; Gail Linda Brown; Martin Oft; Kyriakos P. Papadopoulos
Collaboration
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