Deborah K. Schlossman
Harvard University
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Featured researches published by Deborah K. Schlossman.
Seminars in Ophthalmology | 2014
Nour Maya N. Haddad; Jennifer K. Sun; Samer Abujaber; Deborah K. Schlossman; Paolo S. Silva
Abstract Diabetic patients are known to have an increased risk of cataract development and cataract surgery is a common surgical procedure for diabetic individuals. Cataract extraction (CE) in diabetic patients as compared to non-diabetic patients is associated with higher risks of reported complications such as capsular contraction and opacification as well as post-surgical worsening of macular edema (ME) and diabetic retinopathy (DR). In this paper, we review the pathogenesis of diabetic cataract, the risk factors contributing to cataract complications as well as DR progression, and assess preventive measures and treatment options for DR and ME following CE.
Retina-the Journal of Retinal and Vitreous Diseases | 2014
Paolo S. Silva; Prisca A. Diala; Rola N. Hamam; Paul G. Arrigg; Sabera T. Shah; Timothy L. Murtha; Deborah K. Schlossman; Jerry D. Cavallerano; Jennifer K. Sun; Lloyd Paul Aiello
Purpose: To compare visual acuity outcomes and diabetic retinopathy progression after pars plana vitrectomy (PPV) versus combined pars plana vitrectomy and phacoemulsification (PPVCE) in patients with diabetes. Methods: Retrospective review of 222 consecutive diabetic patients undergoing PPV or PPVCE. Results: A total of 251 eyes of 222 patients were evaluated (PPV = 122, PPVCE = 129). Four-year follow-up was 64% (161 eyes). Overall, patients undergoing PPVCE had better preoperative visual acuity (PPVCE = 20/80, PPV = 20/160, P = 0.03). At 4-year follow-up, visual acuity improved (PPV = +22, PPVCE = +11 letters) compared with baseline in both groups. After correcting for baseline differences in visual acuity, no statistically significant difference in final visual acuity was observed (PPVCE = 20/32, PPV = 20/50, P = 0.09). Results did not differ substantially by surgical indication (vitreous hemorrhage, traction retinal detachment, epiretinal membrane, and/or diabetic macular edema). Cataract progression occurred in 64%, and cataract surgery was performed in 39% of phakic eyes undergoing PPV. Rates of diabetic retinopathy progression, vitreous hemorrhage, and retinal detachment were not statistically different. Neovascular glaucoma developed in 2 patients (2%) after PPV and 6 patients (8%) after PPVCE (P = 0.07). Conclusion: In diabetic patients, equivalent visual acuity improvement over 4 years was observed after PPV or PPVCE. Visual outcomes and retinopathy progression rates were not significantly different after either intervention, suggesting that PPVCE may be appropriate when indicated in patients with diabetes.
Diabetes Care | 2015
Roeland J.W. Middelbeek; Tamarra James-Todd; Jerry D. Cavallerano; Deborah K. Schlossman; Mary-Elizabeth Patti; Florence M. Brown
While the benefits of gastric bypass (GB) surgery in type 2 diabetes are well established, few studies have evaluated the long-term effects of GB in patients with type 1 diabetes (1,2), and these studies demonstrate conflicting effects on glycemic control. This is clinically important given the increasing prevalence of obesity in patients with type 1 diabetes (3). We studied 10 severely obese women with confirmed type 1 diabetes, as previously described (4), and evaluated outcomes prior to GB and at 1 and 5 years following surgery. Mean age at GB was 39.6 ± 8.4 years, mean duration of type 1 diabetes 24.6 ± 10.1 years, and mean age at diagnosis 16.0 ± 8.3 years. Six subjects used continuous subcutaneous insulin infusion. BMI decreased by 33% from baseline at 1 year postoperatively (from 43.5 ± 7.5 to 29.3 ± 5.4 kg/m2, P < 0.0001) but …
Acta Ophthalmologica | 2018
Paolo S. Silva; Aditi Gupta; Radwan Ajlan; Deborah K. Schlossman; Ann Tolson; Jerry D. Cavallerano; Lloyd Paul Aiello
To describe the characteristic retinal features of lipemia retinalis when using ultrawide field scanning laser ophthalmoscopy.
Diabetes Care | 1999
Sven-Erik Bursell; Allen C. Clermont; Lloyd Paul Aiello; Lloyd M. Aiello; Deborah K. Schlossman; Edward P. Feener; Lori Laffel; George L. King
Investigative Ophthalmology & Visual Science | 2013
Nour Maya N. Haddad; Jennifer K. Sun; Michael Molla; Paul G. Arrigg; Sabera T. Shah; Deborah K. Schlossman; Timothy J. Murtha; Edward P. Feener; Lloyd Paul Aiello
Investigative Ophthalmology & Visual Science | 2011
Prisca A. Diala; Paolo S. Silva; Ahmed Z. Soliman; Jennifer K. Sun; Paul G. Arrigg; Sabera T. Shah; Timothy L. Murtha; Deborah K. Schlossman; Rola N. Hamam; Lloyd Paul Aiello
Investigative Ophthalmology & Visual Science | 2008
P. A. Silva; R. N. Haman; Jennifer K. Sun; M. Prakash; N. N. Vaidya; P. G. Arrigg; S. T. Shah; Timothy J. Murtha; Deborah K. Schlossman; Lloyd Paul Aiello
Archive | 2007
Jerry D. Cavallerano; Deborah K. Schlossman; Rola N. Hamam; Lloyd Paul Aiello
Investigative Ophthalmology & Visual Science | 2007
Rola N. Hamam; Paul G. Arrigg; Sabera T. Shah; Deborah K. Schlossman; Timothy J. Murtha; Manvi Prakash; Lloyd M. Aiello; Lloyd Paul Aiello