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Delphine Compere

Pfizer

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Publication

Featured researches published by Delphine Compere.

Bioorganic & Medicinal Chemistry Letters | 2011

Thiophene and bioisostere derivatives as new MMP12 inhibitors.

Matthew Badland; Delphine Compere; Karine Courte; Anne-Claude Dublanchet; Stéphane Blais; Ajith C. Manage; Guillaume Peron; Roger Wrigglesworth

A new MMP12 inhibitor series has been identified containing a thiophene moiety. Different approaches have been considered to replace this potential toxicophore. α-Fluorothiophene derivatives were the most interesting compounds. Their synthesis is presented.

Journal of Molecular Biology | 2004

Crystal Structures of Novel Non-Peptidic, Non-Zinc Chelating Inhibitors Bound to Mmp-12

Renaud Morales; Sophie Perrier; Jean-Michel Florent; Joel Beltra; Sylvie Dufour; Isabelle De Mendez; Peggy Manceau; Anita Tertre; François Moreau; Delphine Compere; Anne-Claude Dublanchet; Margaret O'Gara

Bioorganic & Medicinal Chemistry Letters | 2005

Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors

Anne-Claude Dublanchet; Pierre Ducrot; Charles Andrianjara; Margaret O’Gara; Renaud Morales; Delphine Compere; Alexis Denis; Stéphane Blais; Philippe Cluzeau; Karine Courte; Jacques Hamon; François Moreau; Marie-Laure Prunet; Anita Tertre

Archive | 2003

Novel thiophene derivatives, their process of preparation and the pharmaceutical compositions which comprise them

Anne-Claude Dublanchet; Delphine Compere; Philippe Cluzeau; Stéphane Blais; Alexis Denis; Pierre Ducrot; Karine Courte; Sophie Descamps

Archive | 2004

Thiophene amino acid derivatives, process for preparing them and pharmaceutical compositions containing them

Delphine Compere; Anne-Claude Dublanchet; Karine Courte; Stéphane Blais; Pierre Ducrot; Philippe Cluzeau; Alexis Denis

Archive | 2004

Fluorothiophene derivatives, process for preparing them and pharmaceutical compositions containing them

Delphine Compere; Anne-Claude Dublanchet; Karine Courte; Stéphane Blais

Archive | 2002

New thiophene derivatives, process for their preparation and pharmaceutical compositions containing them

Stéphane Blais; Philippe Cluzeau; Delphine Compere; Anne-Claude Dublanchet

Archive | 2004

5-fluoro-thiopen-compounds,the process for their preparation,the pharmaceutical compositions containing them and their use as metallopotenases inhibitors

Delphine Compere; Anne-Claude Dublanchet; Karine Courte; Stéphane Blais

Journal of Molecular Biology | 2004

Corrigendum to “Crystal Structures of Novel Non-peptidic, Non-zinc Chelating Inhibitors Bound to MMP-12” [J. Mol. Biol. (2004) 341, 1063–1076]

Renaud Morales; Sophie Perrier; Jean-Michel Florent; Joel Beltra; Sylvie Dufour; Isabelle De Mendez; Peggy Manceau; Anita Tertre; François Moreau; Delphine Compere; Anne-Claude Dublanchet; Margaret O'Gara

Archive | 2003

Novel thiophene derivatives, preparation method thereof and pharmaceutical compositions containing same

Anne-Claude Dublanchet; Delphine Compere; Philippe Cluzeau; Stéphane Blais; Alexis Denis; Pierre Ducrot; Karine Courte; Sophie Descamps

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Anne-Claude Dublanchet

Pfizer

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Stéphane Blais

Pfizer

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Karine Courte

Pfizer

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Philippe Cluzeau

Pfizer

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Alexis Denis

Pfizer

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Pierre Ducrot

Pfizer

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Anita Tertre

Pfizer

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François Moreau

Pfizer

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Jean-Michel Florent

Pfizer

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Joel Beltra

Pfizer

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