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Featured researches published by Deng Hongxin.


Acta Obstetricia et Gynecologica Scandinavica | 2007

Expression of human Biot2 and its potential function on carcinogenesis in endometrial cancer

Shen Yangmei; He Xiang; Deng Hongxin; Yang Hanshuo; Peng Feng; Xie Yuping; Wei Yuquan; Zhao Xia

Background. Rat Biot2 is a novel gene first reported and named by our laboratory. We wanted to study the expression profile and reveal the function of its human homologous gene (human Biot2, hBiot2) on carcinogenesis in endometrial cancer. Methods. Using RT‐PCR, we tested hBiot2 expression profile in normal human tissues from infants and adults. Using real‐time RT‐PCR, we tested different expression quantities of hBiot2 between an endometrial cancer group and a normal endometrium group, between different histological grading groups in endometrial cancer, and between different stage groups during the menstrual cycle. RNA‐RNA ISH tested the expression location of hBiot2 in normal and cancer tissues. Results. Three kinds of novel shearings of hBiot2 in different normal tissues were obtained. Normal organs expressing hBiot2 in infants, did not express hBiot2 in adults. hBiot2 expression was higher in endometrial cancer tissue compared to normal endometrium tissue. hBiot2 expression was higher in the Grade 2–3 group with endometrial cancer compared to the Grade 1 group, and it was higher in the proliferative phase than in the secretory phase of a normal endometrium. hBiot2 was expressed mainly in the parenchymal cells. Conclusions. Three shearings of hBiot2 may suggest that it has different functions in different organs. The expression difference of hBiot2 between infants and adults, cancerous and normal tissues, different histological gradings in endometrial cancer, different stages during the menstrual cycle in the normal endometrium suggests that hBiot2 may have the potential to induce carcinogenesis in endometrial cancer.


Archive | 2015

Method for inducing ADSCs (adipose derived stem cells) to differentiate into iHeps in vitro

Deng Hongxin; Deng Jie; Xu Fen; Fu Yanli; Wei Yuquan


Science China-life Sciences | 2016

病院中国西部のトランスレーショナル医療センター【Powered by NICT】

Deng Hongxin; Li Weimin; Wei Yuquan


Archive | 2016

Application of interleukin 35 to preparation of drugs used for treating autoimmune dermatoses, therapeutic drug, and IL-35-Fc fusion protein

Deng Hongxin; Zhang Dunfeng; Li Yiming; Wei Yuquan


Archive | 2016

Application of IL-35 gene in preparing medicine for treating psoriasis and medicine for treating psoriasis

Deng Hongxin; Zhang Junfeng; Wei Yuquan


Archive | 2016

Method for inducing differentiation of hADSCs (human adipose-derived mesenchymal stem cells) to functional iHeps in vitro

Deng Hongxin; Fu Yanli; Deng Jie; Xu Fen; Wei Yuquan


Archive | 2016

Bionic liver as well as preparation method and application thereof

Gou Maling; Deng Hongxin; Wei Yuquan; Xu Fen; Kang Tianyi; Deng Jie


Archive | 2015

Tumor cell vaccine simultaneously secreting PD-1 neutralizing antibody and GM-CSF factor and preparation method thereof

Deng Hongxin; Tian Hongwei; Wei Yuquan


Chinese Journal of Cancer Prevention and Treatment | 2008

Apoptosis of non-small cell lung cancer A549 cells by silencing EGFR with RNA interference

Deng Hongxin


Sichuan Journal of Zoology | 2007

Clone and Preliminary Characterization of a Novel KLP Gene in Zebrafish

Deng Hongxin

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