Denise Mancy | Researchain

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Cellular and Molecular Life Sciences | 1980

Nosiheptide, a sulfur-containing peptide antibiotic isolated from Streptomyces actuosus 40037

F. Benazet; M. Cartier; Jean Florent; Claude Godard; G. Jung; Jean Lunel; Denise Mancy; C. Pascal; J. Renaut; P. Tarridec; J. Theilleux; R. Tissier; M. Dubost; Leon Ninet

Nosiheptide (9671 R.P.) isolated fromStreptomyces actuosus 40037 (NRRL 2954) is a sulfur-containing polypeptidic antibiotic, quite different from all the other members of this family. Very active in vitro against gram-positive bacteria, it is inactive in vivo in experimentally infected mice. Not toxic, even at high dose, it may be used as a feed additive for chickens and pigs and it shows a favourable effect on the growth and conversion index.

Cellular and Molecular Life Sciences | 1976

Emericid, a new polyether antibiotic fromStreptomyces hygroscopicus (DS 24 367)

Leon Ninet; F. Benazet; H. Depaire; Jean Florent; Jean Lunel; Denise Mancy; A. Abraham; J. R. Cartier; N. De Chezelles; Claude Godard; M. Moreau; R. Tissier; J. Y. Lallemand

Emericid is a new polyether polycyclic ionophore antibiotic excreted byStreptomyces hygroscopicus (DS 24 367). Active in vitro against Gram-positive bacteria, it is ineffective in vivo. At a 0.006–0.02% level in the diet it protects chickens and rabbits against coccidiosis.

Cellular and Molecular Life Sciences | 1974