Detlef Axmann

Determination of the minimum number of marginal gap measurements required for practical in-vitro testing.

STATEMENT OF PROBLEM Gap measurements along margins are frequently used to assess the quality of single crowns. However, the number of gap measurements required for clinically relevant results in laboratory studies is not known. PURPOSE This study estimated the minimum number of gap measurements on margins of single crowns to produce relevant results for gap analysis. METHODS AND MATERIAL Ten all-ceramic crowns were fabricated on a master steel die. Gaps along crown margins were investigated in a scanning electron microscope on the master steel die without cementation and on replica dies after conventional cementation. Measurements were made in 100 microm steps according to 3 gap definitions. The initial number of measurements per crown (n = 230) was reduced to smaller subsets using both systematic and random approaches to determine the impact on the quality of results. RESULTS On the data of gap definition 1, reduction from 230 to about 50 measurements caused less than +/-5 microm variability for arithmetic means. Analysis of standard errors showed slowly increasing values smaller than 3 microm, both indicating no relevant impact on the quality of results. Smaller data sizes yielded accelerated increase of standard errors and divergent variabilities of mean. The minimum of 50 measurements did not depend on gap definition or on cementation condition. CONCLUSION Fifty measurements are required for clinically relevant information about gap size regardless of whether the measurement sites are selected in a systematic or random manner, which is far more than what current in vitro studies use.

What are causes and treatment strategies for patellar-tendinopathy in female runners?

Patellar-tendinopathy (PT) is a common overuse injury in long distance runners, especially in women. Until today, no definite combinations of clinical, biomechanical, or training variables, or causative factors in the development of PT have been found. This study focused on assessing the differences in biomechanical characteristics between healthy runners (CO) and runners with PT only. We examined a total of 42 women. 21 CO and 21 PT. 3D kinematics of barefoot running was used in the biomechanical setup. Both groups were matched with respect to height and weight. After determining dropouts due to forefoot running, poor quality of data and lack of matching subjects in CO in terms of body height and weight, the final population comprised 24 subjects (CO=12, PT=12). Biomechanical evaluations indicate eccentric overloading of the quadriceps muscle group (knee extensors), increased pronation velocity as well as a lack of joint coordination as major etiological factors in the development of PT. We assume that eccentric strengthening of the knee extensors, as well as reduction of pronation velocity through orthotics, proper running shoes, and balance training will help treat and possibly prevent PT.

Kinematic classification of iliotibial band syndrome in runners

Several inconsistent causative biomechanical factors are considered to be crucial in the occurrence of iliotibial band syndrome (ITBS). The focus of this study was on assessing differences in the kinematic characteristics between healthy runners [control group (CO)] and runners with ITBS in order to recommend treatment strategies to deal with this injury. Three‐dimensional kinematics of barefoot running was used in the biomechanical setup. Both groups were matched with respect to gender, height and weight. After determining drop outs, the final population comprised 36 subjects (26 male and 10 female): 18 CO and 18 ITBS (13 male and five female, each). Kinematic evaluations indicate less hip adduction and frontal range of motion at the hip joint in runners with ITBS. Furthermore, maximum hip flexion velocity and maximum knee flexion velocity were lower in runners with ITBS. Lack of joint coordination, expressed as earlier hip flexion and a tendency toward earlier knee flexion, was found to be another discriminating variable in subjects with ITBS compared with CO subjects. We assume that an increase in range of motion at the hip joint, stretching of the hip abductors, as well as stretching the hamstrings, calf muscles and hip flexors will help treat ITBS.

The influence of matching populations on kinematic and kinetic variables in runners with iliotibial band syndrome.

The purpose of this study was to assess how participant matching influences biomechanical variables when comparing healthy runners and runners with iliotibial band syndrome (ITBS). We examined 52 healthy runners (CO) and 18 with ITBS, using three-dimensional kinematics and pressure distribution. The study population was matched in three ways and compared with the biomechanical findings: ITBS versus CO I (unmatched), ITBS versus CO II (matched to gender) and ITBS versus CO III (matched to gender, height, and weight). The final number of participants in each group was n = 18. The kinematic variables showed a dependency on the matching process. The largest statistically significant differences (after Bonferroni adjustment) in the frontal and transverse planes were between ITBS and CO III (p = .008). Pressure measurements were also dependent on the matching process, with decreasing and nonsignificant differences (p = .006) between ITBS and CO after refining the process (ITBS vs. CO III). The results of this study and the necessity of matching seem to be plausible (lever arms, different running styles). Data matching is important for understanding overuse injuries in running.

Additive Manufacturing: A Comparative Analysis of Dimensional Accuracy and Skin Texture Reproduction of Auricular Prostheses Replicas

PURPOSE The use of computer-aided design/computer-aided manufacturing (CAD/CAM) and additive manufacturing in maxillofacial prosthetics has been widely acknowledged. Rapid prototyping can be considered for manufacturing of auricular prostheses. Therefore, so-called prostheses replicas can be fabricated by digital means. The objective of this study was to identify a superior additive manufacturing method to fabricate auricular prosthesis replicas (APRs) within a digital workflow. MATERIALS AND METHODS Auricles of 23 healthy subjects (mean age of 37.8 years) were measured in vivo with respect to an anthropometrical protocol. Landmarks were volumized with fiducial balls for 3D scanning using a handheld structured light scanner. The 3D CAD dataset was postprocessed, and the same anthropometrical measurements were made in the CAD software with the digital lineal. Each CAD dataset was materialized using fused deposition modeling (FDM), selective laser sintering (SLS), and stereolithography (SL), constituting 53 APR samples. All distances between the landmarks were measured on the APRs. After the determination of the measurement error within the five data groups (in vivo, CAD, FDM, SLS, and SL), the mean values were compared using matched pairs method. To this, the in vivo and CAD dataset were set as references. Finally, the surface structure of the APRs was qualitatively evaluated with stereomicroscopy and profilometry to ascertain the level of skin detail reproduction. RESULTS The anthropometrical approach showed drawbacks in measuring the protrusion of the ears helix. The measurement error within all groups of measurements was calculated between 0.20 and 0.28 mm, implying a high reproducibility. The lowest mean differences of 53 produced APRs were found in FDM (0.43%) followed by SLS (0.54%) and SL (0.59%)--compared to in vivo, and again in FDM (0.20%) followed by SL (0.36%) and SLS (0.39%)--compared to CAD. None of these values exceed the threshold of clinical relevance (1.5%); however, the qualitative evaluation revealed slight shortcomings in skin reproduction for all methods: reproduction of skin details exceeding 0.192 mm in depth was feasible. CONCLUSION FDM showed the superior dimensional accuracy and best skin surface reproduction. Moreover, digital acquisition and CAD postprocessing seem to play a more important role in the outcome than the additive manufacturing method used.

Measurement error in footwear research biomechanics

Study designs for the biomechanical evaluation of running footwear often encompass repeated measurements of subjects running in a laboratory setup. During post-processing, within-subject variance is usually discarded by pooling subjects’ data, although it can be used in a beneficial way to derive intervals for relevant effect magnitudes. These are essentially required for the a priori calculation of sample size as well as the interpretation of statistical test results. Based on the calculation of the random error component of repeated measurements, a sample dataset on rearfoot eversion measurements was used to demonstrate the concept of detecting practically relevant effect magnitudes. This paper provides calculation procedures as well as the interpretational concept, which can both be easily adapted to many other research scenarios.

Reporting of dental status from full-arch radiographs: Descriptive analysis and methodological aspects.

AIM To identify standards, how entities of dental status are assessed and reported from full-arch radiographs of adults. METHODS A PubMed (Medline) search was performed in November 2011. Literature had to report at least one out of four defined entities using radiographs: number of teeth or implants; caries, fillings or restorations; root-canal fillings and apical health; alveolar bone level. Cohorts included to the study had to be of adult age. Methods of radiographic assessment were noted and checked for the later mode of report in text, tables or diagrams. For comparability, the encountered mode of report was operationalized to a logical expression. RESULTS Thirty-seven out of 199 articles were evaluated via full-text review. Only one article reported all four entities. Eight articles reported at the maximum 3 comparable entities. However, comparability is impeded because of the usage of absolute or relative frequency, mean or median values as well as grouping. Furthermore the methods of assessment were different or not described sufficiently. Consequently, established sum scores turned out to be highly questionable, too. The amount of missing data within all studies remained unclear. It is even so remissed to mention supernumerary and aplased teeth as well as the count of third molars. CONCLUSION Data about dental findings from radiographs is, if at all possible, only comparable with serious limitations. A standardization of both, assessing and reporting entities of dental status from radiographs is missing and has to be established within a report guideline.

Comparison of gait data using two different protocols for ankle joint kinematics

Gait analysis is an important instrument in various fields of clinical research and its protocols are intended to make kinematics interpretable for clinicians. Although they use the same nomenclature for joint angles, different protocols produce different results [1]. The purpose of this study was to compare gait events of the ankle joint to determine differences between two protocols.