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Detlef Grawe

Bayer HealthCare Pharmaceuticals

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Publication

Featured researches published by Detlef Grawe.

Tetrahedron | 1994

Synthesis of 13-ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (desogestrel) and its main metabolite 3-oxo desogestrel

S. Schwarz; Sven Ring; Gisela Weber; Gerhard Teichmüller; Hans-Joachim Palme; Carmen Pfeiffer; Bernd Undeutsch; Bernd Erhart; Detlef Grawe

Abstract A synthesis of the steroid hormone desogestrel (25) from the 18a-homo steroid 1 is described. 25 was transformed into 3-oxo desogestrel (28) by allyl oxidation.

Archive | 2000

Laminates containing an active substance transdermal system

Detlef Grawe; Peter Hoesel; Wilfried Fischer

Archive | 2001

Novel solid body forms of mesoprogestin 11beta-{4e-(hydroxyiminomethyl)-phenyl}-17alpha methoxymethyl-17 beta-methoxy-estra-4,9-dien-3-one

Detlef Grawe; Peter Hösel; Uwe Müller; Gabriele Winter

Archive | 2000

Wirkstoffhaltige Laminate für Transdermalsysteme

Wilfried Fischer; Detlef Grawe; Peter Hösel

Chemical Engineering & Technology | 2012

Equilibrium Model of a Continuous Crystallization Process for Separation of Substances Exhibiting Solid Solutions

Erik Temmel; Uwe Müller; Detlef Grawe; Robert Eilers; Heike Lorenz; Andreas Seidel-Morgenstern

Chemical Engineering Science | 2013

Separation of systems forming solid solutions using counter-current crystallization

Erik Temmel; Sebastian Wloch; Uwe Müller; Detlef Grawe; Robert Eilers; Heike Lorenz; Andreas Seidel-Morgenstern

Archive | 2009

Crystalline active ingredient microparticles, method for producing the same and use thereof in drugs

Detlef Grawe; Sabine Gliesing; Robert Eilers

Archive | 1997

Homogeneous preformulations containing high concentrations of steroids, for producing low-dose solid and semi-solid pharmaceutical preparations

Detlef Grawe; Peter Hoesel; Peter Dr Moellmann; Carsten Timpe; Michael Dittgen; Klaus Matthey

Archive | 2009

Kristalline wirkstoff-mikropartikel, verfahren zu deren herstellung und verwendung in arzneimitteln

Detlef Grawe; Sabine Gliesing; Robert Eilers

Archive | 2001

New solid forms of mesoprogestin 11Beta-[4E-(hydroxyimino methyl)-phenyl]-17alpha-methoxymethyl-17beta-methoxy-estra-4,9-dien-3-on

Detlef Grawe; Peter Hösel; Uwe Müller; Gabriele Winter

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Sabine Gliesing

Schering AG

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Robert Eilers

Bayer Schering Pharma AG

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Hagen Gerecke

Schering AG

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Annette Eichardt

Schering AG

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Uwe Müller

Henkel

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Peter Hösel

Bayer HealthCare Pharmaceuticals

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Carsten Timpe

Schering AG

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Michael Dittgen

Schering AG

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Andreas Seidel-Morgenstern

Max Planck Society

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Erik Temmel

Max Planck Society

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