Dharmendra Jain

Tetralogy of Fallot with Holt-Oram syndrome

Holt-Oram syndrome (HOS) is characterised by mild to severe congenital cardiac defects and skeletal abnormalities of the upper limb. This syndrome is also referred to as Hand-Heart syndrome. The most common cardiac disorder is an ostium secundum detected an atrial septal defect (ASD), followed by ventricular septal defect (VSD) and ostium primum ASD. We report a case of HOS with tetralogy of Fallot (TOF). This association is very rare and is hardly reported in the literature.

Initial presentation with dilated cardiomyopathy in a patient of tuberous sclerosis: a rare case report.

A 35-year-old man presented with dilated cardiomyopathy, an unusual association with tuberous sclerosis. Clinical history and examination were consistent with tuberous sclerosis including major features of tuberous sclerosis complex (TSC) like facial angiofibroma, shagreen patch, subependymal nodules, and angiomyolipoma of kidney. The clinical manifestations, pathogenesis and evaluation of tuberous sclerosis are discussed.

Poor emotional responsiveness in clinical hypertension: Reduced accuracy in the labelling and matching of emotional faces amongst individuals with hypertension and prehypertension

Psychological factors are known to play an important part in the origin of many medical conditions including hypertension. Recent studies have reported elevated blood pressure (even in the normal range of variation) to be associated with a reduced responsiveness to emotions or ‘emotional dampening’. Our aim was to assess emotional dampening in individuals with more extreme blood pressure levels including prehypertensives (N = 58) and hypertensives (N = 60) by comparing their emotion recognition ability with normotensives (N = 57). Participants completed novel facial emotion matching and facial emotion labelling tasks following blood pressure measurement and their accuracy of emotion recognition and average response times were compared. The normotensives demonstrated a significantly higher accuracy of emotion recognition than the prehypertensives and the hypertensives in labelling of facial emotions. This difference generalised to the task where two facial halves (upper & lower) had to be matched on the basis of emotions. In neither the labelling nor matching emotion conditions did the groups differ in their speed of emotion processing. Findings of the present study extend reports of ‘emotional dampening’ to hypertensives as well as to those at-risk for developing hypertension (i.e. prehypertensives) and have important implications for understanding the psychological component of such medical conditions as hypertension.

CSI position statement on management of heart failure in India

Santanu Guha, S. Harikrishnan*, Saumitra Ray, Rishi Sethi, S. Ramakrishnan, Suvro Banerjee, V.K. Bahl, K.C. Goswami, Amal Kumar Banerjee, S. Shanmugasundaram, P.G. Kerkar, Sandeep Seth, Rakesh Yadav, Aditya Kapoor, Ajaykumar U. Mahajan, P.P. Mohanan, Sundeep Mishra, P.K. Deb, C. Narasimhan, A.K. Pancholia, Ajay Sinha, Akshyaya Pradhan, R Alagesan, Ambuj Roy, Amit Vora, Anita Saxena, Arup Dasbiswas, B.C. Srinivas, B.P. Chattopadhyay, B.P. Singh, J. Balachandar, K.R. Balakrishnan, Brian Pinto, C.N. Manjunath, Charan P. Lanjewar, Dharmendra Jain, Dipak Sarma, G. Justin Paul, Geevar A. Zachariah, H.K. Chopra, I.B. Vijayalakshmi, J.A. Tharakan, J.J. Dalal, J.P.S. Sawhney, Jayanta Saha, Johann Christopher, K.K. Talwar, K. Sarat Chandra, K. Venugopal, Kajal Ganguly, M.S. Hiremath, Milind Hot, Mrinal Kanti Das, Neil Bardolui, Niteen V. Deshpande, O.P. Yadava, Prashant Bhardwaj, Pravesh Vishwakarma, Rajeeve Kumar Rajput, Rakesh Gupta, S. Somasundaram, S.N. Routray, S.S. Iyengar, G. Sanjay, Satyendra Tewari, Sengottuvelu G., Soumitra Kumar, Soura Mookerjee, Tiny Nair, Trinath Mishra, U.C. Samal, U. Kaul, V.K. Chopra, V.S. Narain, Vimal Raj, Yash Lokhandwala