Dhirendra S. Bana

HEADACHE DURING HEMODIALYSIS

THE REGULAR Occurrence of severe headache during hemodialysis in a young woman being treated in the Dialysis Unit of Lemuel Shattuck Hospital caused serious problems in the medical management of the patient. This led to the observation that a considerable number of patients suffered headache in a similar fashion during hemodialysis and stimulated the initiation of the present investigation. The material herewith presented deals only with the epidemiology of this complaint and includes such observations as the frequency and nature of the headaches, their relation to the hemodialysis procedure, the medical history of the affected patients, and a discussion of future avenues for research and treatment. Detailed investigation of the biochemical, physiologic and other changes which evolve from the first part of the study as possible etiologic mechanisms will hopefully be the subject of a future report. In addition to the attempt to find a solution to the cause and treatment of headache for the dialysis patient, it seems worthwhile to utilize the unusual opportunity offered by the laboratory setting in which these headaches occur to study the nature and mechanisms of headache itself.

Beta-blockers for migraine.

Sometimes the observations by one astute clinician of one patient lead to new treatments. In 1966, Rabin et al in a study of propranolol to prevent angina, noted that a 59-year-old man reported that his migraines and angina improved on propranolol but the migraines returned after a crossover to placebo medication. Since then, propranolol has become a first-line agent for migraine prevention with increasing caveats, some real, others questionable.

Analgesic Nephropathy and Tumor

Dr. Bana: Mr. B. was thirty-nine years old when he died. When he was six years old, he had polio and was hospitalized for a long, difficult time, since he was the only child of his parents and it was hard for him to be separated from them. At nine years old, he slipped the epiphyses of the femur on both sides. Prolonged hospitalization and recovery were again required. A pattern of dependency and prolonged illness was thus set early in his life.

Endocardial Fibrosis Associated with Methysergide Therapy.

Excerpt Methysergide is probably causally related to the development of cardiac lesions in some patients taking this drug for headaches. We report our observations of the development and progress o...

Expert Opinion: Beta-Blockers for Migraine: March 2008

Sometimes the observations by one astute clinician of one patient lead to new treatments. In 1966, Rabin et al in a study of propranolol to prevent angina, noted that a 59-year-old man reported that his migraines and angina improved on propranolol but the migraines returned after a crossover to placebo medication. Since then, propranolol has become a first-line agent for migraine prevention with increasing caveats, some real, others questionable.

Plasma 18 Hydroxy- II - Deoxycorticosterone In Dialysis Patients With Headache

SYNOPSIS