Dhouha Mansouri

L’hyperplasie pseudo-angiomateuse du stroma mammaire: À propos d’un cas compliqué de gigantomastie

Pseudo-angiomatous hyperplasia of mammary stroma (PASH) is a histopathological entity which is a microscopic fortuitous finding in mammary biopsies performed for different reasons. It may be symptomatic and appears then as a palpable lump. The term pseudo-angiomatous emphasizes the characteristic aspect of the stroma simulating a vascular tumor. We report a case of PASH in a 71 year-old woman who presented a recurring breast mass with rapid swelling of the mammary gland (70 x 60 x 20 cm) treated by mastectomy. PASH must be distinguished from a well-differentiated angiosarcoma. It is ruled out by immunohistochemistry.

Hémangio-endothéliome épithélioïde des tissus mous: À propos d’un cas

Resume Les auteurs rapportent un cas d’hemangio-endotheliome epithelioide des tissus mous survenu chez un homme de 35 ans qui presentait une masse douloureuse du bras droit evoluant depuis deux ans et ayant augmente progressivement de taille. L’imagerie revelait un processus tumoral expansif, mal limite, de 7 cm de grand axe, siegeant au niveau de la loge musculaire interne du bras droit. L’examen histologique de la piece de tumorectomie et l’etude immuno-histochimique ont permis de porter le diagnostic d’hemangio-endotheliome epithelioide des tissus mous. L’evolution postoperatoire a ete marquee par la recidive tumorale au niveau du bras et du creux axillaire droit avec apparition de multiples nodules de permeation au niveau de la paroi thoracique controlaterale et un epanchement pleural droit malgre une chimiotherapie et une radiotherapie adjuvantes. Le patient est decede apres un recul de 2 ans.We report a case of epithelioid hemangioendothelioma observed in soft tissue in a 35-year-old man who presented a painful mass of the right arm which progressed in size for two years. Imaging revealed a 7-cm poorly limited expansive tumor process located in the medial muscle compartment of the right arm. Surgical resection was performed. Histological and immunohistochemical examination led to the diagnosis of soft tissue epithelioid hemangioendothelioma. The tumor recurred in the right arm and the right axillary fossa with development of multiple nodules in the contralateral thoracic wall and pleural effusion. Adjuvant chemotherapy and radiotherapy were performed, but the patient died at two years.