Diane M. Retallack
University of Wisconsin-Madison
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Publication
Featured researches published by Diane M. Retallack.
Microbes and Infection | 1999
Diane M. Retallack; Jon P. Woods
Histoplasma capsulatum, the causative agent of the most common systemic fungal infection, histoplasmosis, has become subject to increasing study in parallel with rising prevalence of human immunodeficiency. This review presents a summary of the advances made in the investigation of H. capsulatum genomics, molecular epidemiology, pathogenesis, and molecular genetics.
Infection and Immunity | 2017
Diego A. Espinosa; Joel Vega-Rodríguez; Yevel Flores-Garcia; Amy R. Noe; Christian Muñoz; Russell John Coleman; Torben R. Bruck; Keith L. Haney; Alex Stevens; Diane M. Retallack; Jeffrey Allen; Thomas S. Vedvick; Christopher B. Fox; Steven G. Reed; Randall F. Howard; Ahmed M. Salman; Chris J. Janse; Shahid M. Khan; Fidel Zavala; Gabriel M. Gutierrez
ABSTRACT Recent studies have shown that immune responses against the cell-traversal protein for Plasmodium ookinetes and sporozoites (CelTOS) can inhibit parasite infection. While these studies provide important evidence toward the development of vaccines targeting this protein, it remains unknown whether these responses could engage the Plasmodium falciparum CelTOS in vivo. Using a newly developed rodent malaria chimeric parasite expressing the P. falciparum CelTOS (PfCelTOS), we evaluated the protective effect of in vivo immune responses elicited by vaccination and assessed the neutralizing capacity of monoclonal antibodies specific against PfCelTOS. Mice immunized with recombinant P. falciparum CelTOS in combination with the glucopyranosyl lipid adjuvant-stable emulsion (GLA-SE) or glucopyranosyl lipid adjuvant-liposome-QS21 (GLA-LSQ) adjuvant system significantly inhibited sporozoite hepatocyte infection. Notably, monoclonal antibodies against PfCelTOS strongly inhibited oocyst development of P. falciparum and Plasmodium berghei expressing PfCelTOS in Anopheles gambiae mosquitoes. Taken together, our results demonstrate that anti-CelTOS responses elicited by vaccination or passive immunization can inhibit sporozoite and ookinete infection and impair vector transmission.
Seminars in Respiratory Infections | 2001
Jon P. Woods; Elizabeth L. Heinecke; Luecke Jw; Maldonado E; Ng Jz; Diane M. Retallack; Michelle M. Timmerman
Infection and Immunity | 2000
Diane M. Retallack; Elizabeth L. Heinecke; Reta S. Gibbons; George S. Deepe; Jon P. Woods
Journal of Bacteriology | 1998
Jon P. Woods; Diane M. Retallack; Elizabeth L. Heinecke; William E. Goldman
Microbial Pathogenesis | 2000
Diane M. Retallack; George S. Deepe; Jon P. Woods
Archive | 2008
Russell John Coleman; Diane M. Retallack; Jane C. Schneider; Thomas Martin Ramseier; Charles Douglas Hershberger; Stacey L. Lee; Sol Resnick
Archive | 2008
Diane M. Retallack; Charles H. Squires; Thomas Martin Ramseier; Russell John Coleman; Jane C. Schneider; Charles Douglas Hershberger
Archive | 2010
Diane M. Retallack; Lawrence C. Chew; Charles H. Squires
Gene | 1999
Diane M. Retallack; Jon P. Woods