Diego Cuccurullo

Advantages and limits of robot-assisted laparoscopic surgery: preliminary experience.

BackgroundIn the last few years, robotics has been applied in clinical practice for a variety of laparoscopic procedures. This study reports our preliminary experience using robotics in the field of general surgery to evaluate the advantages and limitations of robot-assisted laparoscopy.MethodsThirty-two consecutive patients were scheduled to undergo robot-assisted laparoscopic surgery in our units from March 2002 to July 2003. The indications were cholecystectomy, 20 patients; right adrenalectomy, two points; bilateral varicocelectomy, two points; Heller’s cardiomyotomy, two points; Nissen’s fundoplication, two points; total splenectomy, one point; right colectomy, one point; left colectomy, 1 point; and bilateral inguinal hernia repair, one point. In all cases, we used the da Vinci surgical system, with the surgeon at the robotic work station and an assistant by the operating table.ResultsTwenty-nine of 32 procedures (90.6%) were completed robotically, whereas three were converted to laparoscopic surgery. Conversion to laparoscopy was due in two patients to minor bleeding that could not be managed robotically and to robot malfunction in the third patient. There were no deaths. Median hospital stay was 2.2 days (range, 2–8).ConclusionsThe main advantages of robot-assisted laparoscopic surgery are the availability of three-dimensional vision and easier instrument manipulation than can be obtain with standard laparoscopy. The learning curve to master the robot was ≥ 10 robotic procedures. The main limitations are the large diameter of the instruments (8 mm) and the limited number of robotic arms (maximum, three). We consider these technical shortcomings to be the cause for our conversions, because it is difficult to manage bleeding episodes with only two operating instruments. The benefit to the patient must be evaluated carefully and proven before this technology can become widely accepted in general surgery.

International multicenter trial on clinical natural orifice surgery--NOTES IMTN study: preliminary results of 362 patients.

Objectives: Natural orifice translumenal endoscopic surgery (NOTES) is evolving as a promising alternative for abdominal surgery. IMTN Registry was designed to prospectively document early results of natural orifice surgery among a large group of clinical cases. Methods: Sixteen centers from 9 countries were approved to participate in the study, based on study protocol requirements and local institutional review board approval. Transgastric and transvaginal endoscopic natural orifice surgery was clinically applied in 362 patients. Intraoperative and postoperative parameters were prospectively documented. Results: Mean operative time for transvaginal cholecystectomy was 96 minutes, compared with 111 minute for transgastric cholecystectomy. A general complication rate of 8.84% was recorded (grade I-II representing 5.8%, grade III-IV representing 3.04%). No requirement for any analgesia was found in one fourth of cholecystectomy and appendectomy patients. Conclusions: Results of clinical applications of NOTES in the IMTN Study showed the feasibility of different methods of this new minimally invasive alternative for laparoscopic and open surgery.

Technical standardization of laparoscopic splenectomy: experience with 105 cases.

BackgroundSome reports have suggested that laparoscopic splenectomy (LS) can be successfully performed in adults. However, several aspects of this procedure remain as yet undefined; therefore, several attempts have been made to modify the standard technique to try to optimize the procedure. Herein we analyze our experience with 105 laparoscopic splenectomies.MethodsFrom 1993 to 2000, 105 patients underwent LS at our hospital. Twelve of these patients also underwent a concomitant cholecystectomy. There were 66 women and 39 men whose ages ranged between 4 and 78 years (median, 27.7). All patients underwent an elective laparoscopic splenectomy. Seventy five patients had thrombocytopenia (ITP), 14 had hereditary spherocytosis, eight were affected by β-thalassemia, two had splenic cysts, two had lymphoma, (two had myeloid chronic leukemia, one patient presented with a splenic abscess and one had incurred an iatrogenic spleen lesion during adrenalectomy. The first patients in this series were positioned in dorsal decubitus; however, as the team’s experience increased, the right lateral decubitus became the position of choice because it provides better exposure of the splenic hilum. This procedure requires the use of only four trocars.ResultsMean operating time was 95 min (range, 35-320). Hospital stay ranged from 2 to 21 days (median, 4.5). There was only one conversion to open surgery. One patient died in the postoperative period due to the evolution of a preexisting malignant disease. We recorded nine complication-four subphrenic abscesses, two cases of pleuritis, two episodes of postoperative bleeding, and one intestinal infarction 16 days after surgery. Only two patients needed redo surgery.ConclusionsWe believe that the laparoscopic approach is a valid alternative to open splenectomy, but mastery of some of the technical details of this procedure could greatly help avoid its complications. On the basis of our experience, it seems that the lateral approach should be considered the position of choice because it provides exposure and easier dissection of the splenic hilar structures. We also found that a 30° scope and an ultrasonic dissector allowed for perfect vision and optimal hemostasis during the procedure. At the end of procedure, the spleen should be fragmented and then extracted using an extraction bag.

Distal pancreas surgery: outcome for 19 cases managed with a laparoscopic approach.

BackgroundIn the past decade, laparoscopy has shown its efficacy also for advanced surgery. In this report, the authors retrospectively review their experience with the distal pancreas.MethodsFrom April 1999 to October 2004, 19 patients underwent a laparoscopic procedure for pathologies of the distal pancreas. The authors performed one distal pancreatectomy (DP) with conservation of the spleen and section of the splenic vessels, four distal splenopancreatectomies (DSP), one DSP plus a left adrenalectomy, two enucleations, seven DPs with conservation of the spleen and the splenic vessels, and four cystojejunostomies.ResultsOne procedure was converted to open surgery because of a hemorrhagic complication. No other significant intraoperative complications occurred. The postoperative course was characterized by one bleed managed conservatively, two pancreatic fistulas (one requiring a second operation), one abscess drained under echographic view, and one reactive pancreatitis. The mean postoperative stay was 8.5 days. The histologic report showed 16 benign diseases and 3 malignant tumors. The mean follow-up period was of 42 months. The patient who had DP spleen preservation with section of the splenic vessels reported mild pain in the left hypochondrium, probably attributable to chronic splenic ischemia, during the first 3 postoperative months. One incisional hernia occurred in the patient who underwent conversion to an open procedure, and one patient affected by adenocarcinoma died 10 months after the operation.ConclusionsThe authors can affirm that laparoscopy for the distal pancreas is a successful procedure in terms of results and surgical feasibility. Prospective studies are necessary to confirm their positive impression.

Laparoscopic approach to gastric remnant-stump: our initial successful experience on 3 cases.

Introduction Laparoscopic treatment of gastric adenocarcinoma is still a debated issue. In this paper, we retrospectively reviewed 3 cases of laparoscopic treatment of gastric remnant-stump adenocarcinoma. We analyzed the feasibility, the postoperative outcome, and the short-term results. Materials and Methods From January 2003 to September 2005, we carried out 3 laparoscopic completion gastrectomies for cancer of the remnant stomach. All patients were males, between 59 and 73 years old. All of them had a previous history of benign gastric ulcer that required a Billroth II subtotal gastrectomy. We always performed a D2 lymphadenectomy and a Roux an Y side-to-side esophagojejunostomy. Results No conversion was necessary. Mean operative time was 210 minutes (range: 160 to 260 min). No intraoperative transfusions were applied. We had 1 postoperative bleeding managed conservatively with 2 units of blood transfusion. In 1 case, the esophageal transit study showed a tiny anastomotic leak, not clinically evident, which was managed conservatively. The mean peristalsis was present at 56 hours (range: 48 to 72 h). The mean postoperative stay was 11 days (range: 8 to 18 d). In all cases, histologic examination was positive for adenocarcinoma. The mean number of lymph nodes was 18 (range: 12 to 26). The TNM status was: T2N0M0, T3N0M0, and T3N1M0. Resection margins were negative in all cases (R0). The mean follow-up was 17.6 months (range: 11 to 24 mo). The patient with positive lymph node died 11 months after the operation for metastatic disease. Conclusions In our preliminary experience, laparoscopic treatment of gastric remnant-stump adenocarcinoma has been demonstrated to be technically feasible and sure. The histologic examination confirmed a proper surgical dissection. Also, if it is an initial experience, we believe that laparoscopy could be considered a valid opportunity to open surgery.

Laparoscopic splenectomy for the treatment of wandering spleen

Wandering spleen is a very rare pathologic condition that initially presents with unremarkable clinical symptoms, then dramatically manifests severe complications. A case of wandering spleen treated with laparoscopic splenectomy is described and compared with other similar reports in the literature. Laparoscopic exploration of the abdominal cavity allowed the diagnosis to be confirmed and splenectomy to be performed. An enlarged spleen led to the choice of total splenectomy to avoid both future complications and future organ torsion resulting from the long and twisted vascular pedicle. The laparoscopic approach led to a rapid recovery, a 3-day postoperative course, and satisfactory cosmetic results.

Robotic single‐access splenectomy using the Da Vinci Single‐Site® platform: a case report

Single‐access laparoscopic splenectomy can offer patients some advantages. It has many difficulties, such as instrument clashing, lack of triangulation, odd angles and lack of space. The Da Vinci Single‐Site® robotic surgery platform could decrease these difficulties. We present a case of single‐access robotic splenectomy using this device.

Laparoscopic total gastrectomy in gastric cancer: Our experience in 92 cases

Abstract Introduction: Laparoscopic total gastrectomy (LTG) is seldom used for gastric cancer because the complex vascularization and lymphatic drainage makes lymphadenectomy and esophagojejunal anastomosis difficult and requires special skills. Our aim was to demonstrate the feasibility and accuracy of LTG in gastric cancer with D2 lymphadenectomy. Material and methods: Eighty-eight LTG and four laparoscopic remnant gastrectomies (LRGs) were performed over >12 years. The median patient age was 64 years, and the male/female ratio was 1.49/1. Eighty-seven patients had a D2 and only five patients had a D1 lymphadenectomy. We propose the retrospective analysis of intra- and perioperative mortality and morbidity. Results: In only four of 96 cases approached by laparoscopy, a conversion to laparotomy was needed. There were two (2.17%) perioperative deaths in 92 procedures and few complications. Histological data show 79 advanced gastric cancers (AGC), 11 early gastric cancers (EGC), and two gastric diffused lymphomas. The five-year Kaplan-Meier overall survival in patients with EGC and AGC was 100% and 58%, respectively. Conclusions: The results demonstrate the feasibility of an oncologically correct minimally invasive total gastrectomy. We would like to promote comparisons among different institutions to achieve better standardization of indications and techniques for a laparoscopic approach to gastric cancer.

Irreversible electroporation for locally advanced pancreatic cancer through a minimally invasive surgery supported by laparoscopic ultrasound

Highlights • We report on the application of Irreversible electroporation (IRE) on locally advanced pancreatic cancer (LAPC).• We report on a minimally invasive surgical approach supported by laparoscopic ultrasound.• We report on a novel technique the benefits of IRE with the advantages of laparoscopic surgery.• In medical literature is in our knowledge the first experience.

The Role of Laparoscopy in Emergency Treatment of Complications after Laparoscopic and Endoscopic Procedures

Since its introduction in the late 1980s, the evolution and increasing diffusion of laparoscopic surgery has allowed the realization of a growing number of minimally invasive surgical techniques, thanks to improved technology, in terms of instruments and image transmission. Without doubt, all major abdominal surgery can be performed with a laparoscopic approach and laparoscopy is now the gold standard for surgical treatment in an increasing number of diseases [1].