Dillon T. Browne

Prenatal maternal mood is associated with altered diurnal cortisol in adolescence

BACKGROUND Experimental animal work shows that prenatal stress has a persisting effect on the hypothalamic-pituitary-adrenal (HPA) axis of offspring. The implications of these findings for human health and development are not yet clear. METHODS The data are based on the ALSPAC cohort, a prospective longitudinal study of a community sample that has followed mothers and children from pregnancy. When the children were aged 15 years, diurnal cortisol samples were collected at wake-up, 30 min post-awakening and at afternoon and evening times on up to three consecutive days on n=889 adolescents. Diurnal cortisol was predicted from prenatal anxiety and depression, obstetric, life-style, socio-demographic, and postnatal covariates. RESULTS Multilevel model analysis indicated that maternal prenatal anxiety was associated with a modest alteration of diurnal cortisol, indexed by a reduced cortisol awakening response and flatter diurnal slope. The effects were independent of psychosocial and obstetric covariates and measures of maternal postnatal anxiety; effects were similar for prenatal maternal depression. There was no association between adolescent cortisol and paternal prenatal anxiety. CONCLUSIONS There are small but persisting associations between maternal prenatal mood and diurnal cortisol in the child that persist into adolescence and may constitute a programming effect.

Relations between parenting and child behavior : exploring the child's personality and parental self-efficacy as third variables

The present study explores the bidirectional associations between parental behavior and child externalizing behavior in the context of two intervening variables: child’s personality as a moderator of the effect of parental behavior on later child behavior; and parental self-efficacy as a mediator of the effect of child behavior on later parental behavior. Data were collected twice within one year from a sample of 340 preschoolers and their parents. Using latent variable SEM, three models were computed separately for mother—child and father—child dyads. A bidirectional effect was verified for the mothers, but only a child effect was observed for the fathers. Expected mediation by self-efficacy was verified. Finally, a partial moderating role for child’s personality was demonstrated.

The Role of Parental Personality Traits in Differential Parenting

Significant relationships have been demonstrated between parental personality and parenting toward individual children, but there is little research exploring the relationship between parental personality and differential parenting (DP). The present study examined the relationship between the Big Five personality dimensions and differential positivity and negativity in parenting (observed and self-report measures). The analyses are based on a sample of 867 children nested within 381 families. Using multilevel modeling and controlling for child age, gender, birth order, behavior, and family socioeconomic status analyses revealed that maternal and paternal agreeableness were inversely related to reports of differential positivity. Agreeableness predicted observed differential negativity, and the relationship was curvilinear (at both high and low levels of agreeableness, differential negativity was higher). Finally, mothers with the most openness to experience exhibited the highest levels of reported differential negativity. The findings suggest that parental personality is a modest yet important influence to consider when conceptualizing the sources of DP.

Parental differential treatment, child’s externalizing behavior and sibling relationships: Bridging links with child’s perception of favoritism and personality, and parents’ self-efficacy

This study examined the associations between parental differential treatment (PDT), children’s externalizing behavior (EB), and sibling relationships, as well as the intervening effects of children’s perceptions of favoritism, personality, and parents’ self-efficacy (SE). A total of 117 families having a child clinically referred for EB problems were studied. First, the role of PDT and perceived favoritism on EB and sibling relationships was examined. PDT was moderately related to both EB and sibling affection. Perception of favoritism was only predictive of sibling hostility. Second, EB effects on PDT were examined and the mediating role of parents’ SE within this relation was explored. EB predicted higher level PDT in parents and the link between PDT and EB was mediated by parental SE.

System Integration and Its Influence on the Quality of Life of Children with Complex Needs

Purpose. To explore the interactions between child and parents psychosocial factors and team integration variables that may explain improvements in physical dimensions of the PEDS QL quality of life of children with complex needs after 2 years. Methods. In this 2-year study, parents were identified by the Childrens Treatment Network. Families were eligible if the child was aged 0–19 years, had physical limitations, resided in either Simcoe County or the Region of York, Ontario, and there were multiple other family needs. Regression analysis used to explore associations and interactions; n = 110. Results. A childs physical quality of life was affected by interacting factors including childs behavior, parenting, and integrated care. Statistically significant interactions between team integration, processes of care, and child/parent variables highlight the complexity of the rehabilitation approach in real-life situations. Conclusions. Rehabilitation providers working with children with complex needs and their families should also address child and parent problematic behaviors. When this was the case in high integrated teams, the childs physical quality of life improved after two years.

Normal birth weight variation and children's neuropsychological functioning: links between language, executive functioning, and theory of mind.

The effect of low birth weight on childrens development has been documented for a range of neurocognitive outcomes. However, few previous studies have examined the effect of birth weight variability within the normal range on childrens neuropsychological development. The current study examined birth weight variation amongst children weighing ≥2500 g in relation to their language, executive functioning (EF), and theory of mind (ToM), and specified a developmental pathway in which birth weight was hypothesized to be associated with childrens EF and ToM through their intermediary language skills. The current study used a prospective community birth cohort of 468 children. Families were recruited when children were newborns and followed up every 18 months until children were age 4.5. Language was assessed at age 3 using a standardized measure of receptive vocabulary (PPVT), and EF and ToM were measured at age 4.5 using previously validated and developmentally appropriate tasks. After controlling for potential confounding variables (family income, parent education, gestational age), birth weight within the normal range was associated with language ability at age 3 (β=.17; p=.012); and the effect of birth weight on both EF (z=2.09; p=.03) and ToM (z=2.07; p=.03) at age 4.5 operated indirectly through their language ability at age 3. Our findings indicate that the effects of birth weight on child neurocognition extend into the normal range of birth weight, and specific developmental mechanisms may link these skills over time.

Health across early childhood and socioeconomic status: Examining the moderating effects of differential parenting

Variations in parenting within the family (i.e. differential parenting) are associated with various domains of child adjustment, whereby disfavoured siblings exhibit poorer social and emotional outcomes. To date there is no research examining the effects of differential parenting on childrens general health, or the way in which differential parenting interacts with socioeconomic markers to predict general health over time. The present study assessed 501 Canadian families at 2 time points separated by 18 months. Differential maternal negativity predicted worse health 18 months later. Moreover, the association between maternal education and child health was strongest when children were also exposed to high levels of differential negativity. Findings indicate that multiple forms of social disadvantage (i.e. between families and between siblings) can operate independently or in a cumulative fashion to predict health across early childhood.

Birth Weight Variability and Language Development: Risk, Resilience, and Responsive Parenting

OBJECTIVE This study examined whether birth weight variation within the normal range was associated with language ability at 36 months, and whether responsive parenting-the putative protective factor-buffered children from the risk of relatively low birth weight. METHODS In all, 467 community mother-child dyads were followed longitudinally from birth. Receptive language was measured at 36 months. Responsive parenting was assessed through observed interactions at 18 months and examined as the hypothesized moderator. RESULTS Controlling for confounds, both birth weight and responsive parenting positively predicted childrens language skills. There was also a significant interaction between birth weight and responsive parenting-higher responsivity was associated with better language ability, and this link was especially pronounced for children at risk owing to relatively low birth weight. CONCLUSION Normative differences in birth weight are a source of variability in childrens language, but postnatal socialization factors such as parenting may buffer this risk.

A Randomized Trial of Wraparound Facilitation Versus Usual Child Protection Services

Objective: To evaluate whether the addition of a wraparound facilitator to regular child protection services improved child and family functioning over 20 months. Method: A single blind randomized controlled trial with concealment and stratification across three sites (N = 135 eligible families with substantiated maltreatment). Results: Based on 2 × 2 mixed analysis of variance and intention to treat, both groups improved in child impairments, d = −.60 [−.81, −.39], caregiver psychological distress, d = −.33 [−.52, −.13], and family resources, d = .44 [.27, .62]. No measurable benefit was associated with the intervention (e.g., child impairments, d = .14 [−.12, .52]). However, treatment fidelity analysis revealed that many components of wraparound were either missing or present in both groups. Conclusions: The presence of a facilitator alone did not appear to improve child or family functioning if the various components of wraparound were not adequately implemented.

Prosocial skills may be necessary for better peer functioning in children with symptoms of disruptive behavior disorders

Children with disruptive behavior disorders experience substantial social challenges; however, the factors that account for (i.e., mediate), or influence (i.e., moderate), peer problems are not well understood. This study tested whether symptoms of Oppositional Defiant Disorder and Conduct Disorder were associated with peer impairment and whether prosocial skills mediated or moderated these associations. Teacher ratings were gathered for 149 children (Mage = 9.09, SD = 1.71, 26% female) referred for behavioral concerns to an urban child psychiatry clinic. Path-analytic linear regressions testing mediation and moderation effects showed that prosocial skills significantly moderated the negative effects of symptoms of Conduct Disorder on peer impairment. Children showed less peer impairment only when they had relatively few conduct symptoms and high prosocial skills. Measurement of prosocial skills, in addition to conduct problems, may best capture factors which contribute to peer problems of children with disruptive behaviors.