Dina Sharhan

Are ultrasound renal aspects associated with urinary biochemistry in fetuses with lower urinary tract obstruction

To evaluate the association between ultrasonographic renal parameters and urine biochemistry in fetuses with lower urinary tract obstruction (LUTO).

OP11.06: Do placental and amniotic membrane pathological changes occur following open and fetoscopic neural tube defect (NTD) repair?: Short oral presentation abstracts

one showed a fluctuant colour, between bright red and dark purple (bidirectional flow), which is rare in this type of anastomoses that usually have unidirectional flow. Results: In 9 of the 10 cases, there was intrauterine demise of the sick twin within the next 4 weeks after surgery. The changing colour in the AV anastomosis which is supposed to be unidirectional, was due to the low central blood pressure of the premortem small twin which turns into a low vascular pressure in the chorionic arterial branch too low to overcome the pressure of the chorionic vein branch of the normal twin at the level of the AV anastomosis. Conclusions: MCDA twin pregnancies complicated with a severe sFGR type II with no superimposed TTTS and that showed during Fetoscopic surgery a fluctuant change of colour at the level of an AV anastomosis had a high mortality rate of the small twin.

OP23.08: Longitudinal growth evaluation in fetuses with neural tube defect with and without prenatal-fetoscopic and open-repair

Objectives: An interstitial laser ablation becomes a good candidate for the prenatal treatment of chorioangioma, sacrococcygeal teratoma, selective fetal growth restriction and twin reversed arterial perfusion sequence in early gestation. The aim of this study was to describe the in vitro results of interstitial laser coagulation in different types of laser generator, power and time. Methods: Total 144 placentae were interstitially ablated with PlexoLong 19 gauge needle, 400 micron laser fiber and Nd:YAG or Diode at 12 power-time combinations (5, 10, 15 seconds versus 15, 20, 25, 30 watts). We evaluated the diameter of coagulated zone using ultrasound and histopathology. Results: Mean coagulated placental diameter (ultrasound) was shown in figure 1. Ablated size measurement by ultrasound was slightly larger than microscopy (p<0.001). The average length (histopathology) after 5, 10 and 15 seconds of coagulation were 5.12, 7.00 and 7.85 mm (±0.16), and after using power 15, 20, 25 and 30 watt were 5.20, 6.36, 7.08 and 7.99 mm (±0.21), respectively. In addition, using the Diode was significantly wider than using Nd:YAG in coagulated diameter (p<0.001). Histology of the placental tissue showed gradual change in degree of thermal damage and period of time. Conclusions: Interstitial laser ablation particular Diode, seems to be an effective prenatal treatment when the feeding vessels are smaller than 8 mm in diameter.