Dinesh C. Bhunia

PMA‐SiO2: A Heterogenous Catalyst for O‐, S‐, and N‐Nucleophilic Substitution Reactions of Aryl Propargyl Alcohols

Abstract Aryl‐propargylic alcohols undergo O‐, S‐, and N‐nucleophilic substitution reactions in the presence of a catalytic amount of PMA‐SiO2.

First stereoselective total synthesis of cryptomoscatone E1 and synthesis of (+)-goniothalamin via an asymmetric acetate aldol reaction

A stereoselective total synthesis of (+)-goniothalamin and cryptomoscatone E1 have been described. The synthetic strategy involves an asymmetric acetate aldol reaction, Evans acetal intramolecular oxa-Michael reaction, ring-closing metathesis, Horner–Wadsworth–Emmons reaction and lactonization as the key steps.