Djibril Faye

Ionic liquid supported organotin reagents to prepare molecular imaging and therapy agents

Efficiency of ionic liquid supported organotin reagents in halodemetalation reaction has been investigated. High radiochemical yields of astatinated and iodinated compounds have been obtained using simple work-up procedure. This methodology represents a straightforward approach for the preparation of molecular imaging and therapy agents in nuclear medicine.

Bis-EDOT end capped by n-hexyl or n-hexylsulfanyl groups: the effect of the substituents on the stability of the oxidized states

Three bis-EDOT derivatives end capped with n-hexyl or n-hexylsulfanyl groups have been synthesized. The oxidation processes of these compounds have been studied using cyclic voltammetry and UV-Vis-NIR spectroscopy. The strong influence of the sulfur atoms of the hexylsulfanyl chains for stabilizing the oxidation states is evidenced. Thus, it is shown that the two compounds grafted with one or two hexylsulfanyl groups are reversibly oxidized into cation radical and dication states. By contrast, compounds end capped with hexyl groups present a fast σ-dimerization of the radical cation. The reduction of the σ-dimer to give the neutral bis-EDOT derivative is slow.

Specific (bio-)chemical sensing with organic microlasers

Monitoring of environmental pollutants present at low concentrations requires creation of miniature, low-cost, and highly sensitive detectors that are capable to specifically identify target substances. We propose a detection approach based on refractive index sensing with polymer micro-lasers. The sensitivity and specificity of the detection is improved due to a functionalization of the microcavity material which allows specific detection of target molecules (here, heavy metal ions).