Do Kyu Pyun | Researchain

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Synthetic Communications | 2001

PRACTICAL SYNTHESIS OF ETHYL CIS-4-AMINO-3-METHOXY-1-PIPERIDINE CARBOXYLATE, A KEY INTERMEDIATE OF CISAPRIDE

Bong Jin Kim; Do Kyu Pyun; Hee J. Jung; Hyun Jeong Kwak; Jae H. Kim; Eun J. Kim; Won Jang Jeong; Cheol Hae Lee

A practical synthesis of ethyl cis-4-amino-3-methoxy-1-piperidinecarboxylate 1, a key intermediate of cisapride as a potent gastrointestinal stimulant, has been accomplished from 1-methyl-1,2,3,6-tetrahydropyridine 2 via an efficient formation of cis-fused oxazolidinopiperidine 7.

Journal of Organic Chemistry | 2003

Novel stereoselective synthesis of functionalized oxazolidinones from chiral aziridines

Chan Sun Park; Min Sung Kim; Tae Bo Sim; Do Kyu Pyun; Cheol Hae Lee; Daeock Choi; Won Koo Lee; Jae Won Chang; Hyun Joon Ha

Organic Letters | 2003

Synthesis of Highly Enantioenriched All-Carbon Quaternary Centers: Conjugate Additions of Chiral Organolithium Nucleophiles to α,α-Dinitrile β,β-Disubstituted Olefins

Doo Ok Jang; Dwight D. Kim; Do Kyu Pyun; Peter Beak

Organic Letters | 2001

Synthesis of Substituted-(l)-Tryptophanols from an Enantiomerically Pure Aziridine-2-methanol

Do Kyu Pyun; Cheol Hae Lee; Hyun-Joon Ha; Chan Sun Park; Jae-Won Chang; Won Koo Lee

Chemical & Pharmaceutical Bulletin | 2002

Syntheses of 1β-Methylcarbapenems Bearing 5-Methyl-4-hydroxypyrrolidinone

Do Kyu Pyun; Bong Jin Kim; Hee Jung Jung; Jae Hak Kim; Jin Soo Lee; Won Koo Lee; Cheol Hae Lee

Synlett | 2001

2,3-Dihydro-4H-1,3-oxazin-4-ones, Novel Auxiliaries for the Stereoselective Synthesis of 1β-methylcarbapenems

Do Kyu Pyun; Won Jang Jeong; Hee J. Jung; Jae H. Kim; Jin S. Lee; Cheol Hae Lee; Bong Jin Kim

Heterocycles | 2001

Stereoselective Synthesis of a Novel Tetracyclic b-Lactam

Bong Jin Kim; Do Kyu Pyun; Hee Jung Jung; Hyun Jung Kwak; Jae Hak Kim; Eun Jung Kim; Moon Hwan Kim; Cheol Hae Lee

Bioorganic & Medicinal Chemistry Letters | 2000

Synthesis and antibacterial activity of 2α-functionalized 1β-methylcarbapenems related to KR-21012

Hyun Jeong Kwak; Do Kyu Pyun; Jae H. Kim; Eun J. Kim; Hee J. Jeong; Bong Jin Kim; Cheol Hae Lee

Heterocycles | 2001

Stereoselective Synthesis of a Novel Tetracyclic β-Lactam

Do Kyu Pyun; Hee Jung Jung; Hyun Jung Kwak

Bulletin of The Korean Chemical Society | 1998

The Thiazole Route to 2-Formyl-1

Jin Soo Lee; Do Kyu Pyun; Won Koo Lee; Cheol Hae Lee

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