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Dive into the research topics where Domenico Lepori is active.

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Featured researches published by Domenico Lepori.


Journal of Ultrasound in Medicine | 2002

Slipping rib syndrome: a place for sonography in the diagnosis of a frequently overlooked cause of abdominal or low thoracic pain

Jean-Yves Meuwly; Stephan Wicky; Pierre Schnyder; Domenico Lepori

To describe the sonographic appearance of a poorly recognized cause of low thoracic or upper abdominal pain.


Physics in Medicine and Biology | 2004

A new test phantom with different breast tissue compositions for image quality assessment in conventional and digital mammography

Marc Pachoud; Domenico Lepori; Jean-François Valley; Francis R. Verdun

Our objective is to describe a new test phantom that permits the objective assessment of image quality in conventional and digital mammography for different types of breast tissue. A test phantom, designed to represent a compressed breast, was made from tissue equivalent materials. Three separate regions, with different breast tissue compositions, are used to evaluate low and high contrast resolution, spatial resolution and image noise. The phantom was imaged over a range of kV using a Contour 2000 (Bennett) mammography unit with a Kodak MinR 2190-MinR L screen-film combination and a Senograph 2000D (General Electric) digital mammography unit. Objective image quality assessments for different breast tissue compositions were performed using the phantom for conventional and digital mammography. For a similar mean glandular dose (MGD), the digital system gives a significantly higher contrast-to-noise ratio (CNR) than the screen-film system for 100% glandular tissue. In conclusion, in mammography, a range of exposure conditions is used for imaging because of the different breast tissue compositions encountered clinically. Ideally, the patient dose-image quality relationship should be optimized over the range of exposure conditions. The test phantom presented in this work permits image quality parameters to be evaluated objectively for three different types of breast tissue. Thus, it is a useful tool for optimizing the patient dose-image quality relationship.


Physics in Medicine and Biology | 2005

A comparison of the performance of modern screen-film and digital mammography systems

Pascal Monnin; Gutierrez D; S Bulling; Domenico Lepori; Jean-François Valley; Francis R. Verdun

This work compares the detector performance and image quality of the new Kodak Min-R EV mammography screen-film system with the Fuji CR Profect detector and with other current mammography screen-film systems from Agfa, Fuji and Kodak. Basic image quality parameters (MTF, NPS, NEQ and DQE) were evaluated for a 28 kV Mo/Mo (HVL = 0.646 mm Al) beam using different mAs exposure settings. Compared with other screen-film systems, the new Kodak Min-R EV detector has the highest contrast and a low intrinsic noise level, giving better NEQ and DQE results, especially at high optical density. Thus, the properties of the new mammography film approach those of a fine mammography detector, especially at low frequency range. Screen-film systems provide the best resolution. The presampling MTF of the digital detector has a value of 15% at the Nyquist frequency and, due to the spread size of the laser beam, the use of a smaller pixel size would not permit a significant improvement of the detector resolution. The dual collection reading technology increases significantly the low frequency DQE of the Fuji CR system that can at present compete with the most efficient mammography screen-film systems.


Journal of Thoracic Imaging | 1996

Helical CT angiography for traumatic aortic rupture: correlation with aortography and surgery in five cases.

Pierre Schnyder; Laurent Chapuis; Bernadette Mayor; Reto Meuli; Stephan Wicky; Domenico Lepori; Axel Essinger

Dynamic computed tomography (CT) is frequently performed to assess the mediastinum in trauma patients with a suspected thoracic aortic rupture. Its usefulness lies in demonstrating a mediastinal hematoma. However, many patients still undergo conventional aortography despite a normal chest CT, because of a perceived insensitivity of this technique for diagnosing aortic rupture. One application of helical CT is CT angiography, in which multiple thin sections are acquired through a blood vessel during the injection of iodinated contrast. Good demonstration of vascular pathology can be achieved, especially with 3-D reconstructions. This article reviews a series of four surgically proven thoracic aortic ruptures studied using helical CT, and one case proven to be false-positive by both helical CT angiography and conventional angiography. Correlation between conventional and helical CT angiography was excellent, with similar findings and the same interpretation pitfalls. Helical CT is fast and noninvasive. Combined examination of other anatomical areas can be performed in the same procedure in major trauma patients. Helical CT may potentially decrease the need for aortography in these acutely injured patients.


Physics in Medicine and Biology | 2005

A comparison of the imaging characteristics of the new Kodak Hyper Speed G film with the current T-MAT G/RA film and the CR 9000 system

Pascal Monnin; Gutierrez D; S Bulling; Domenico Lepori; Francis R. Verdun

Three standard radiation qualities (RQA 3, RQA 5 and RQA 9) and two screens, Kodak Lanex Regular and Insight Skeletal, were used to compare the imaging performance and dose requirements of the new Kodak Hyper Speed G and the current Kodak T-MAT G/RA medical x-ray films. The noise equivalent quanta (NEQ) and detective quantum efficiencies (DQE) of the four screen-film combinations were measured at three gross optical densities and compared with the characteristics for the Kodak CR 9000 system with GP (general purpose) and HR (high resolution) phosphor plates. The new Hyper Speed G film has double the intrinsic sensitivity of the T-MAT G/RA film and a higher contrast in the high optical density range for comparable exposure latitude. By providing both high sensitivity and high spatial resolution, the new film significantly improves the compromise between dose and image quality. As expected, the new film has a higher noise level and a lower signal-to-noise ratio than the standard film, although in the high frequency range this is compensated for by a better resolution, giving better DQE results--especially at high optical density. Both screen-film systems outperform the phosphor plates in terms of MTF and DQE for standard imaging conditions (Regular screen at RQA 5 and RQA 9 beam qualities). At low energy (RQA 3), the CR system has a comparable low-frequency DQE to screen-film systems when used with a fine screen at low and middle optical densities, and a superior low-frequency DQE at high optical density.


European Radiology | 2003

Prospective comparison of MR enteroclysis with multidetector spiral-CT enteroclysis: interobserver agreement and sensitivity by means of "sign-by-sign" correlation

Sabine Schmidt; Domenico Lepori; Jean-Yves Meuwly; Bertrand Duvoisin; Reto Meuli; Pierre Michetti; Christian Felley; Pierre Schnyder; Guy van Melle; Alban Denys


Pediatrics | 2004

Brain Perfusion in Children: Evolution With Age Assessed by Quantitative Perfusion Computed Tomography

Max Wintermark; Domenico Lepori; Jacques Cotting; Eliane Roulet; Guy van Melle; Reto Meuli; Philippe Maeder; Luca Regli; Francis R. Verdun; Thierry Deonna; Pierre Schnyder; François Gudinchet


European Radiology | 2002

Paranasal sinuses in children: size evaluation of maxillary, sphenoid, and frontal sinuses by magnetic resonance imaging and proposal of volume index percentile curves

Barghouth G; Prior Jo; Domenico Lepori; Duvoisin B; Pierre Schnyder; François Gudinchet


European Radiology | 2004

Management of patient dose and image noise in routine pediatric CT abdominal examinations

Francis R. Verdun; Domenico Lepori; Pascal Monnin; Jean-François Valley; Pierre Schnyder; François Gudinchet


European Journal of Radiology | 2008

Detection of ingested cocaine-filled packets—Diagnostic value of unenhanced CT

Sabine Schmidt; Olivier Hugli; Elena Rizzo; Domenico Lepori; F. Gudinchet; Bertrand Yersin; Pierre Schnyder; Jean-Yves Meuwly

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Reto Meuli

University Hospital of Lausanne

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